[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633187":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":24,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":55,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":24,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":38,"whyStopped":24,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Superior University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CVE","EXPERIMENTAL","Participants in this arm will receive rehabilitation through a Collaborative Virtual Reality Environment (CVE), where both the patient and therapist interact simultaneously within a shared virtual space. The intervention is delivered using a head-mounted display-based system that enables real-time communication, guidance, and feedback.\n\nThe rehabilitation program consists of task-specific, goal-oriented exercises targeting upper limb function, gait, balance, and functional mobility. Activities are designed to simulate real-world movements and include object manipulation, reaching tasks, and controlled walking scenarios. The therapist actively supervises and adapts the exercises during each session, ensuring appropriate progression based on patient performance.\n\nThe collaborative nature of the environment facilitates increased engagement, motor learning, and adherence by incorporating interactive elements and immediate corrective feedback. The intervention follows structured progressio",[13],"Other: Collaborative Virtual Environment",{"label":15,"type":6,"description":16,"interventionNames":17},"NIVR","Participants in this arm will undergo rehabilitation using a Non-Immersive Virtual Reality (NIVR) system delivered through a standard screen-based interface. The intervention without the use of head-mounted displays or real-time collaborative features.\n\nThe rehabilitation program includes task-oriented exercises focusing on upper limb function, balance, gait-related activities, and overall functional mobility. These exercises are designed to replicate real-world movements and are performed in a structured and repetitive manner to promote motor learning.\n\nParticipants will perform the activities independently with periodic supervision from a therapist. Feedback is primarily system-generated, and progression is based on predefined levels of difficulty within the software. The intervention emphasizes consistency, task specificity, and gradual progression throughout the study",[18],"Other: Non-Immersive Virtual Reality (NIVR)",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Collaborative Virtual Environment","Collaborative Virtual Reality Environment (CVE), participants perform exercises within a shared virtual space alongside a therapist, enabling real-time interaction, guidance, and adaptive feedback.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Non-Immersive Virtual Reality (NIVR)","Physiotherapy-based rehabilitation delivered through a screen-based virtual environment, involving structured, task-oriented exercises performed with limited therapist interaction",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Hafiz Muddassir Riaz","CONTACT","+923456627409","muddassir.riaz@gmail.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":24},"Punjab Institute of Neurosciences Lahore","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":45,"coordinates":46},"Point",[47,48],74.35071,31.558,{"lat":48,"lon":47},{"type":51,"investigatorFullName":31,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Principal Investigator (PI)","100633187","collaborative-vs-non-immersive-vr-in-parkinsons-rehabilitation-100633187",false,"NCT07523425","Collaborative vs Non-Immersive VR in Parkinson's Rehabilitation","COMPARATIVE EFFECTIVENESS of COLLABORATIVE VIRTUAL ENVIRONMENT and NON-IMMERSIVE VIRTUAL REALITY in the REHABILITATION of PATIENTS With PARKINSON'S DISEASE","CVE vs NIVR","Inclusion Criteria:\n\n* Male and Female\n* Age: 45 years-80 Years\n* Diagnosed patients of idiopathic Parkinson Disease with minor to moderate severity according to the Hoehn \\& Yahr stages I-III.\n* On conventional and stable medical treatment at present\n* No severe cognitive impairments (MMSE ≥ 24).\n* Ability to participate in virtual rehabilitation sessions\n* Willingness to participate and provide informed consent\n\nExclusion Criteria:\n\n* Severe visual, auditory, or motor impairments unrelated to Parkinson's.\n* Fear of virtual environment.\n* Comorbidities that hinder participation in the treatment (e.g., advanced dementia).\n* Severe musculoskeletal conditions limiting movement\n* History of epilepsy or conditions contraindicating virtual reality exposure\n* Participation in another interventional study within the last 3 months","ALL","45 Years","80 Years",{"count":65,"type":66},60,"ESTIMATED","INTERVENTIONAL",[69],"NA","This randomized controlled trial aims to compare the effectiveness of a Collaborative Virtual Reality Environment (CVE) and Non-Immersive Virtual Reality (NIVR) in the rehabilitation of patients with Parkinson's disease. Participants with mild to moderate disease severity will be randomly assigned to either the CVE group or the NIVR group.\n\nThe CVE intervention will involve therapist-guided, interactive virtual exercises in a shared environment, promoting real-time engagement and feedback. The NIVR group will perform task-oriented exercises using screen-based virtual reality without immersive and collaborative features.\n\nBoth interventions will be delivered over an 12-week period. Primary outcomes will assess motor function using standardized clinical scales, while secondary outcomes will evaluate cognitive function, mobility, and quality of life.\n\nThe study seeks to determine whether collaborative and interactive virtual rehabilitation provides superior clinical outcomes compared to conventional non-immersive virtual approaches in patients with Parkinson's disease.",[72],"Parkinson Desease",[74,75,76,77,78],"Parkinson Disease","Collaborative Virtual Reality Evinronment","Non Immersive Virtual Reality","Rehabilitation","Motor Control","2026-04-11",{"date":81,"type":82},"2026-04-15","ACTUAL",{"date":84,"type":82},"2025-05-27",{"date":86,"type":66},"2026-09-30",{"name":5,"class":6},1]