[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100547371":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":19,"locations":29,"responsibleParty":45,"collaborators":18,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":18,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":32,"whyStopped":18,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University Hospital, Tours","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patient with programmed surgery","Patient programmed with surgery of meatotomy, septoplasty or turbinoplasty, or other programmed surgeries",[12],"Other: Collection of nasal cells during programme surgery",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Collection of nasal cells during programme surgery","During programmed surgery (meatotomy, septoplasty or turbinoplasty for example, or other programmed surgeries), the surgeon will take an atraumatic sample from the nasal cavity using a dedicated device (brush) from the healthy nasal mucosa.",[9],null,[20,25],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},"Charles Aussedat, MD","CONTACT","0247474747","c.aussedat@chu-tours.fr",{"name":26,"role":22,"phone":27,"phoneExt":18,"email":28},"Adeline Mousset","0218370645","a.fourmy@chu-tours.fr",[30],{"facility":31,"status":32,"city":33,"state":18,"zip":18,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"AUSSEDAT","RECRUITING","Tours","France","FR",{"type":37,"coordinates":38},"Point",[39,40],0.70398,47.39484,{"lat":40,"lon":39},[43],{"name":44,"role":22,"phone":18,"phoneExt":18,"email":18},"CHARLES AUSSEDAT",{"type":46,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100547371","collection-of-primary-human-100547371",false,"NCT06407102","Collection of Primary Human","Collection of Primary Human Nasal Epithelial Cells","BIONOSE","Inclusion Criteria:\n\n* Adult patients (age \\> 18 years) whose native language is French, or who understands French.\n* Affiliation with a French social security system (CMU accepted).\n* Informed consent, written and signed by the participant.\n* Planned rhinological surgery (meatotomy, septoplasty or turbinoplasty for example, but other surgeries as well)\n\nExclusion Criteria:\n\n* Patients under court protection, guardianship or curatorship.\n* Pregnant or breast-feeding women (positive pregnancy test for women of childbearing age).\n* Patients presenting a major alteration of the mucosa or a malignant rhinosinus pathology.",true,"ALL","18 Years","90 Years",{"count":60,"type":61},100,"ESTIMATED","INTERVENTIONAL",[64],"NA","Treatment and prevention of respiratory infections are of great interest in many medical areas. Create a physical device covered by primary human nasal cells could be very usefull in order to analyse delivery and efficiency of drugs. In this context the aim of this project is to create a collection of primary cells from the human nasal epithelium.\n\nThis collection will be realised during programmed surgery, thanks to a specific device dedicated to collect nasal cells. Then the cells will be sent to the lab in order to grow at the air-liquid interface, which is an excellent 'ex vivo' model for their study.",[67],"Nasal Disease",[69,70],"nasal cells","Respiratory epithelium","2026-06-12",{"date":73,"type":74},"2026-06-16","ACTUAL",{"date":76,"type":74},"2024-12-06",{"date":78,"type":61},"2028-05-02",{"name":5,"class":6},1]