[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602657":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":29,"locations":24,"responsibleParty":35,"collaborators":24,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":24,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":62,"whyStopped":24,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":24},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"S-PRG-Barrier coat ,Shofu Inc. Kyoto, Japan","ACTIVE_COMPARATOR","A light-cured Giomer varnish for prolonged hypersensitivity relief. Seals and protects exposed dentinal tubules to prevent pain. Ideal for patients experiencing loss of enamel, gingival recession or temporary sensitivity due to whitening.",[13],"Other: S-PRG Barrier coat",{"label":15,"type":16,"description":17,"interventionNames":18},"S-PRG PROPHYLAXIS PASTE","EXPERIMENTAL","S-PRG PROPHYLAXIS PASTE is a bioactive Giomer-based paste containing S-PRG particles that release six therapeutic ions-fluoride, strontium, borate, aluminum, sodium, and silicate each contributing to remineralization, antibacterial effects, and dentin sensitivity reduction.",[19],"Other: S-PRG Prophylaxis paste",[21,25],{"type":6,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"S-PRG Barrier coat",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"S-PRG Prophylaxis paste","S-PRG Prophylaxis paste is a bioactive Giomer-based paste containing S-PRG particles that release six therapeutic ions-fluoride, strontium, borate, aluminum, sodium, and silicate each contributing to remineralization, antibacterial effects, and dentin sensitivity reduction.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"engy hassan aref abdelaziz engy aref, bachelor degree (BDS)","CONTACT","01126538662","engy.aref@dentistry.cu.edu.eg",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Engy hassan aref abdelaziz","Dr. Engy Hassan Aref","100602657","color-stability-of-s-prg-resin-based-light-cure-varnish-and-prophylaxis-paste-on-white-spot-lesions-100602657",false,"NCT07126366","Color Stability of S-PRG Resin-Based Light-Cure Varnish and Prophylaxis Paste on White Spot Lesions","COLOR STABILITY OF S-PRG RESIN-BASED LIGHT CURE VARNISH AND PROPHYLAXIS PASTE ON WHITE SPOT LESIONS: A 12-MONTH RANDOMIZED CLINICAL TRIAL","Inclusion Criteria:\n\n* Patient consulting in the outpatient clinic.\n* Enamel caries in anterior permanent teeth according to ICDAS-1 and ICDAS-2.\n* Good oral hygiene.\n* Provide informed consent.\n* Cooperative and willing to participate in the trial.\n* Male or female.\n* Adult patients aged 16 to 35 years.\n\nExclusion Criteria:\n\n* Spontaneous or elicited pain from caries.\n* Tooth mobility.\n* Signs of pulpal infection.\n* Severe medical conditions that would not allow management in the clinic.\n* Hereditary developmental defects such as amelogenesis imperfecta or dentinogenesis imperfecta.\n* Known allergies or sensitivities to dental materials, including fluoride\n* Inability to return for recall visits.\n* Poor oral hygiene.\n* Refusal to participate in the study.",true,"ALL","16 Years","35 Years",{"count":51,"type":52},58,"ESTIMATED","INTERVENTIONAL",[55],"NA","The aim of the study is to evaluate and compare the long-term color stability of two bioactive materials used in the management of white spot lesions: Surface Pre-Reacted Glass (S-PRG) containing resin-based light-cured varnish and S-PRG containing prophylaxis paste. The study will assess color changes over a 12-month period to determine which material better maintains aesthetic integrity while providing therapeutic benefits for demineralized enamel surfaces.",[58],"White Spot Lesion of Tooth",[60,61],"S-PRG","White spot lesion","NOT_YET_RECRUITING","2025-08-10",{"date":65,"type":66},"2025-08-17","ACTUAL",{"date":68,"type":52},"2025-09-21",{"date":70,"type":52},"2026-10-21",{"name":5,"class":6}]