[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544488":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":65,"collaborators":26,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":26,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University Hospital, Ghent","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active tDCS group","ACTIVE_COMPARATOR","Patients will receive active tDCS during the therapy.",[13],"Device: Active tDCS",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham tDCS group","SHAM_COMPARATOR","Patients will receive sham tDCS during the therapy.",[19],"Device: Sham tDCS",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Active tDCS","During the whole therapy period, active tDCS group will receive active tDCS after CBT. They also receive active home-based tDCS.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham tDCS","The sham tDCS group will receive sham tDCS after CBT. They also receive sham home-based tDCS.",[15],[32],{"name":33,"affiliation":34,"role":35},"Chris Baeken","University Ghent","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+32476209841","Chris.Baeken@ugent.be",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Sara De Witte","+32498382824","sara.dewitte@ugent.be",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"University Hospital Ghent","RECRUITING","Ghent","East-Flanders","9000","Belgium","BE",{"type":55,"coordinates":56},"Point",[57,58],3.71667,51.05,{"lat":58,"lon":57},[61,63],{"name":62,"role":38,"phone":26,"phoneExt":26,"email":26},"Chris Baeken, Prof.",{"name":64,"role":38,"phone":26,"phoneExt":26,"email":26},"Josefien Dedoncker, M.Sc.",{"type":66,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100544488","combination-of-neurostimulation-and-psychotherapy-to-stop-worrying-100544488",false,"NCT06369532","Combination of Neurostimulation and Psychotherapy to Stop Worrying","Stop Worrying, Learn to Let go Through a Combination of Neurostimulation and Psychotherapy","Inclusion Criteria:\n\n* Generalized anxiety disorder (GAD)\n* Depressive disorder\n\nExclusion Criteria:\n\n* other psychiatric pathology than GAD or depression screened by senior psychiatrist by means of the Mini-International Neuropsychiatric Interview (MINI) and psychiatric anamnesis\n* Abuse of alcohol, drugs or medication other than prescribed by general practitioner or psychiatrist\n* no consent to participate in measurement (questionnaire, fNIRS or EEG)\n* Insufficient knowledge of the current language (Dutch)\n* Acute or chronic suicidality\n* Acute psychosis or manic depressive disorder\n* Inability to commit to 8 sessions of Cognitive-Behavioral Therapy (CBT) or receive 4 weeks of transcranial Direct Current Stimulation (tDCS).","ALL","18 Years","70 Years",{"count":78,"type":79},85,"ESTIMATED","INTERVENTIONAL",[82],"NA","This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with the symptom of high rumination. High ruminators will be included (Group1, active tDCS-CBT group; Group2, sham tDCS-CBT group). All patients will receive active or sham tDCS.",[23,28],[86],"transcranial direct current stimulation","2026-03-11",{"date":89,"type":90},"2026-03-12","ACTUAL",{"date":92,"type":90},"2024-03-06",{"date":94,"type":79},"2027-12-20",{"name":5,"class":6},1]