[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637837":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":55,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":78,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Saint Joseph's University, Philadelphia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"FES and tDCS","EXPERIMENTAL","The tDCS was applied as a bilateral montage with the anode of the tDCS device (ActivaDose II, ActivaTek Inc., Salt Lake City, Utah, USA) applied to the involved hemisphere and the cathode over the unaffected hemisphere. The dosage of the tDCS device was one mA for 60 minutes for the duration of the gait training delivered via a pair of sponge electrodes moistened with 0.9% NaCl solution. The exact locations for the electrode placements were based on a 20-point electrode system, in which we chose two points that targeted the motor cortex region corresponding to the left lower limb. Treatments were performed twice weekly over the 8 weeks.\n\nThe FES was administered to the tibialis anterior muscle of the impaired lower extremity with one electrode over the common peroneal nerve at the head of the fibula and the other over a motor point in the middle of the muscle belly of the tibialis anterior muscle.",[13],"Behavioral: Standard protocol for combo of FES and tDCS",{"label":15,"type":16,"description":17,"interventionNames":18},"FES with tDCS subthreshold","ACTIVE_COMPARATOR","The tDCS was applied as a bilateral montage with the anode of the tDCS device (ActivaDose II, ActivaTek Inc., Salt Lake City, UT, USA) applied to the involved hemisphere and the cathode over the unaffected hemisphere. The dosage of the tDCS device was set initially at one mA for 60 minutes and then for the duration of the gait training the machine was turned to subthreshold levels, delivered via a pair of sponge electrodes moistened with 0.9% NaCl solution. The exact locations for the electrode placements were based on a 20-point electrode system, in which we chose two points that targeted the motor cortex region corresponding to the left lower limb. Treatments were performed twice weekly over the 8 weeks.\n\nThe FES was administered to the tibialis anterior muscle of the impaired lower extremity with one electrode over the common peroneal nerve at the head of the fibula and the other over a motor point in the middle of the muscle belly of the tibialis anterior muscle.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Standard protocol for combo of FES and tDCS","The gait training consisted of treadmill training with forward and backward ambulation with speed progression as appropriate, ambulation over obstacles, ramp ambulation forwards and backwards, and stair ambulation up and down. In each condition, cues were to increase toe clearance on the affected limb and achieve heel strike at initial contact. Vitals were collected at the start and end of each session, and heart rate was measured at the end of each activity, along with the Rating of Perceived Exertion (RPE), to determine whether the participant was working at a higher intensity than baseline.",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Gregory Thielman, EdD","Saint Joseph's University","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Greg Thielman, EdD","CONTACT","8562667863","gthielman@sju.edu",{"name":38,"role":34,"phone":39,"phoneExt":25,"email":40},"Sylvester Carter, PhD","215 596 7087","scarter1@sju.edu",[42],{"facility":29,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":25},"RECRUITING","Philadelphia","Pennsylvania","19104","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-75.16362,39.95238,{"lat":53,"lon":52},{"type":56,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100637837","combined-functional-electrical-and-transcranial-direct-current-stimulation-for-foot-drop-100637837",false,"NCT07592221","Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop","Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop: A Case Series","tDCS","Inclusion Criteria: To participate, you must be:\n\n* 18 years or older\n* Have had 1 or more strokes (\\> 6 months) affecting ankle dorsiflexion.\n* Discharged from all rehabilitative services.\n* Can walk independently with\u002Fwithout using an assistive device such as a cane without an ankle-foot orthosis (AFO) for 15 minutes.\n\nExclusion Criteria: You must not have:\n\n* An inability to repeat and understand 2-step commands.\n* Peripheral neuropathy\n* Damage to the skull or scalp, such as a fracture History of seizures or epilepsy Extremely high or low blood pressure or heart rate Chest pain or shortness of breath when you are resting Botox injections to your leg or foot in the last 4 months","ALL","18 Years",{"count":68,"type":69},30,"ESTIMATED","INTERVENTIONAL",[72],"NA","This study aims to determine if combining the treatments of transcranial direct current stimulation (tDCS) and functional electrical stimulation (FES) will better help persons with stroke who have difficulty lifting their toes. As part of the treatment, subjects will receive electrical stimulation through pads on their scalp (similar to what one may have received in physical therapy previously to an arm or leg). This protocol is called transcranial direct current stimulation (tDCS). Subjects will also receive electrical stimulation through pads on their leg. This is called functional electrical stimulation (FES). During treatment sessions, subjects will also perform leg activity\u002Fstrengthening exercises. The aim is to evaluate whether combining FES and tDCS within a PT session would reduce foot drop as indicated by improvements in the amount of toe clearance and ankle motion persons with stroke.",[75,76,77],"Falls","Foot Drop","Post Stroke Recovery",[79,80,81],"transcranial direct current stimulation","functional electrical stimulation","minimum toe clearance","2026-05-11",{"date":84,"type":85},"2026-05-18","ACTUAL",{"date":87,"type":69},"2026-06-01",{"date":89,"type":69},"2029-08-30",{"name":5,"class":6},1]