[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580480":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":30,"centralContacts":37,"locations":43,"responsibleParty":59,"collaborators":30,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":30,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":30,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":30,"overallStatus":45,"whyStopped":30,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Kafrelsheikh University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group ITD","EXPERIMENTAL","Patients will receive 15mg in 3ml hyperbaric bupivacaine intrathecally with 5 μg in 0.5ml dexmedetomidine + adductor canal block using 20 ml saline 0.9% at the end of surgery",[13],"Drug: Intrathecal Dexmedetomidine",{"label":15,"type":16,"description":17,"interventionNames":18},"Group ACB","ACTIVE_COMPARATOR","Patients will receive 15mg in 3ml hyperbaric bupivacaine intrathecally with 0.5ml saline 0.9% + adductor canal block using 20 ml bupivacaine 0.25% at the end of surgery.",[19],"Drug: Adductor Canal Block",{"label":21,"type":10,"description":22,"interventionNames":23},"Group ITD+ACB","Patients will receive 15mg in 3ml hyperbaric bupivacaine intrathecally with 5 μg in 0.5ml dexmedetomidine + adductor canal block using 20 ml bupivacaine 0.25% at the end of surgery.",[24],"Drug: Intrathecal Dexmedetomidine + Adductor Canal Block",[26,31,34],{"type":27,"name":28,"description":11,"armGroupLabels":29,"otherNames":30},"DRUG","Intrathecal Dexmedetomidine",[9],null,{"type":27,"name":32,"description":17,"armGroupLabels":33,"otherNames":30},"Adductor Canal Block",[15],{"type":27,"name":35,"description":22,"armGroupLabels":36,"otherNames":30},"Intrathecal Dexmedetomidine + Adductor Canal Block",[21],[38],{"name":39,"role":40,"phone":41,"phoneExt":30,"email":42},"Sherif K Arafa, MD","CONTACT","00201005714014","Sherifhafez1980@gmail.com",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Kafr ash Shaykh","Kafrelsheikh","33516","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],30.93991,31.11174,{"lat":55,"lon":54},[58],{"name":39,"role":40,"phone":41,"phoneExt":30,"email":42},{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Sherif Kamal Arafa","Assistant Professor of Anesthesiology, Surgical Intensive Care and Pain Management Department, Faculty of Medicine, KafrElsheikh University, KafrElsheikh, Egypt.","100580480","combined-intrathecal-dexmedetomidine-and-adductor-canal-block-for-analgesia-after-total-knee-arthroplasty-100580480",false,"NCT06837844","Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty","Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 75 years.\n* Both sexes.\n* American Society of Anesthesiology (ASA) physical status I-II.\n* Scheduled for total knee arthroplasty under spinal anesthesia.\n\nExclusion Criteria:\n\n* Patients with neurological or intellectual disability.\n* History of allergy to local anesthetics or dexmedetomidine .\n* Infection at the injection site.\n* Prolonged use of analgesic or sedative medications.\n* Coagulation abnormalities.\n* Pregnancy.\n* Obesity \\[body mass index (BMI) \\> 30 kg\u002Fm2\\].","ALL","18 Years","75 Years",{"count":74,"type":75},75,"ESTIMATED","INTERVENTIONAL",[78],"NA","The aim of this work is to evaluate the effect of combined intrathecal dexmedetomidine and adductor canal block for analgesia after total knee arthroplasty (TKA).",[28,32,81,82],"Analgesia","Total Knee Arthroplasty","2025-02-20",{"date":85,"type":86},"2025-02-21","ACTUAL",{"date":83,"type":86},{"date":89,"type":75},"2025-08-01",{"name":5,"class":6},1]