[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630334":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":36,"centralContacts":45,"locations":55,"responsibleParty":70,"collaborators":36,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":36,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":36,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":98,"whyStopped":36,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"The Hong Kong Polytechnic University","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"Visual Tetanic Stimulation (VTS)","EXPERIMENTAL","Participant will receive 5 training sessions with VTS: about 1 hour per session",[13],"Other: VTS",{"label":15,"type":16,"description":17,"interventionNames":18},"Transcranial direct current stimulation (NIBS)","ACTIVE_COMPARATOR","Participant will receive 5 training sessions with NIBS: about 1 hour per session",[19],"Other: NIBS",{"label":21,"type":10,"description":22,"interventionNames":23},"Transcranial direct current stimulation+ Visual Tetanic Stimulation (NIBS+VTS)","Participant will receive 5 training sessions with NIBS+VTS: about 1 hour per session",[24],"Other: NIBS+VTS",{"label":26,"type":27,"description":28,"interventionNames":29},"Sham","PLACEBO_COMPARATOR","Participant will receive 5 training sessions with Sham: about 1 hour per session",[30],"Other: Sham",[32,37,40,43],{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"NIBS","Around 1 hour",[15],null,{"type":6,"name":38,"description":34,"armGroupLabels":39,"otherNames":36},"VTS",[9],{"type":6,"name":41,"description":34,"armGroupLabels":42,"otherNames":36},"NIBS+VTS",[21],{"type":6,"name":26,"description":34,"armGroupLabels":44,"otherNames":36},[26],[46,51],{"name":47,"role":48,"phone":49,"phoneExt":36,"email":50},"Ming Yan Cheong, PhD","CONTACT","852-27666108","allen.my.cheong@polyu.edu.hk",{"name":52,"role":48,"phone":53,"phoneExt":36,"email":54},"Lok Hin Chan, BSc (Hons) in Optometry","852-34002309","lhinchan@polyu.edu.hk",[56],{"facility":5,"status":36,"city":57,"state":36,"zip":36,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Hong Kong","HK",{"type":60,"coordinates":61},"Point",[62,63],114.17469,22.27832,{"lat":63,"lon":62},[66,68],{"name":67,"role":48,"phone":49,"phoneExt":36,"email":50},"Allen Cheong, PhD",{"name":69,"role":48,"phone":53,"phoneExt":36,"email":54},"Marco Chan, BSc (Hons) in Optometry",{"type":71,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Allen MY Cheong","Assoc. Head (Academic Programmes and Clinical Training), Prog. Leader [BSc (Hons) in Optometry; MSc in Vision Science and Innovation] & Professor","100630334","combined-non-invasive-brain-and-visual-stimulation-for-vision-improvement-100630334",false,"NCT07486323","Combined Non-Invasive Brain and Visual Stimulation for Vision Improvement","Evaluation of Combined Non-invasive Brain Stimulation (NIBS) and Visual Tetanic Stimulation (VTS) for Vision Enhancement: A Randomized, Single-blind, Cross-over Trial","Inclusion Criteria:\n\n* Age range from 18 to 80 years;\n* Diagnosis of primary open angle or normal tension glaucoma with relative scotoma in both eyes;\n* A relative scotoma defined as a Humphrey Field Analyser (HFA) threshold perimetry loss (mean deviation of -6dB) within the central 24 degree of the visual field for at least one eye;\n* Best-corrected distance visual acuity of 6\u002F12 or better (equivalent to 0.3 logMAR acuity or better to confirm that participant's central vision is preserved).\n* Stable vision and visual field loss for at least 3 months;\n* With a cognitive functional score of 22 or above in the Montreal Cognitive Assessment - Hong Kong version (HK-MoCA) (to confirm participant's intact cognitive function).\n\nExclusion Criteria:\n\n* Ocular diseases other than glaucoma (e.g. age-related macular degeneration, diabetic retinopathy, moderate to severe cataract) or severe hearing impairment (to ensure that participant can hear the instructions clearly during assessments and training);\n* Severe medical problems (e.g. stroke, Parkinson's disease) or self-reported neurological (e.g. brain surgery, brain tumor, peripheral neuropathy), or cognitive disorders (e.g. diagnosed dementia or cognitive impairment);\n* Self-reported vestibular or cerebellar dysfunction, history of vertigo;\n* Using any medications for any neurological conditions or psychiatric drugs (e.g. sedative, hypnotic) that might interfere motor control;\n* Contraindications for non-invasive brain stimulation.","ALL","40 Years","80 Years",{"count":85,"type":86},56,"ESTIMATED","INTERVENTIONAL",[89],"NA","Glaucoma is a complex disease that can result in progressive vision loss. It is the second leading cause of blindness, accounting for 23% of permanent blindness in Hong Kong. There are no treatments that restore vision lost to glaucoma. This study will examine the effect of transcranial direct current stimulation (NIBS) on improving quality of life, visual function and functional performance in patients with peripheral field loss due to glaucoma.",[92],"Glaucoma Open-Angle",[94,95,96,97],"tDCS","transcranial electrical stimulation","visual tetanic stimulation","alpha frequency stimulation","NOT_YET_RECRUITING","2026-03-23",{"date":101,"type":102},"2026-03-24","ACTUAL",{"date":104,"type":86},"2026-04-20",{"date":106,"type":86},"2027-07-10",{"name":5,"class":6},1]