[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100576641":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":64,"collaborators":68,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":25,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":84,"maxAge":25,"enrollmentInfo":85,"targetDuration":25,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":96,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Georgia State University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"VLNC with message campaign","EXPERIMENTAL","Participants in this arm will receive VLNCs during weekly visits and be exposed to messaging about VLNCs and reduced nicotine policy through multiple formats, including inserts placed in cigarette packs, printed advertisements, and videos presented during weekly visits.",[13],"Behavioral: VLNC messages",{"label":15,"type":6,"description":16,"interventionNames":17},"VLNC only","Participants in this arm will receive VLNCs during weekly visits but will not receive any messaging related to cigarettes or reduced nicotine policy. Instead, they will only be exposed to control messages, such as advertisements for bottled water, during weekly visits.",[18],"Behavioral: Control message",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","VLNC messages","Participants will be exposed to messaging about VLNCs and reduced nicotine policy through multiple formats, including inserts placed in cigarette packs, printed advertisements, and video materials presented during their weekly visits.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Control message","Participants will be exposed to control messages, such as advertisements for bottled water, during their weekly visits.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Lyudmila Popova, Ph.D.","CONTACT","404-413-9338","lpopova1@gsu.edu",[37,53],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Georgia State university","RECRUITING","Atlanta","Georgia","30303","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-84.38798,33.749,{"lat":49,"lon":48},[52],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"facility":54,"status":39,"city":40,"state":41,"zip":55,"country":43,"countryCode":44,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"Emory University","30322",{"type":46,"coordinates":57},[48,49],{"lat":49,"lon":48},[60],{"name":61,"role":33,"phone":62,"phoneExt":25,"email":63},"Nicholas Giordano, Ph.D.","404-727-7980","nicholas.a.giordano@emory.edu",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Lyudmila Popova","Associate Professor",[69,70,72],{"name":54,"class":6},{"name":71,"class":6},"University of South Carolina",{"name":73,"class":74},"National Cancer Institute (NCI)","NIH","100576641","communicating-about-nicotine-reduction-in-cigarettes-100576641",false,"NCT06787937","Communicating About Nicotine Reduction in Cigarettes","Communicating About Nicotine and Differential Risks of Tobacco Products in Priority Populations","Inclusion Criteria:\n\n* Age 21+ years\n* Current smoker (self-report as having smoked 100 cigarettes in their lifetime and currently smoking on 27+ days out of past 30, expired breath carbon monoxide \\[CO\\] ≥6ppm to assess regular smoking)\n* Can speak, read, and write in English\n* Available for period of study\n* Willing to try novel research cigarettes\n\nExclusion Criteria:\n\n* Pregnancy or lactation\n* Member of the same household as a study subject\n* Unwilling to use research cigarettes as part of the trial",true,"ALL","21 Years",{"count":86,"type":87},1230,"ESTIMATED","INTERVENTIONAL",[90],"NA","The goal of this clinical trial is to learn how a messaging campaign about reduced nicotine cigarettes and policy, combined with the use of very low nicotine cigarettes (VLNCs), affects smoking behavior and attitudes among adult smokers. The study also aims to assess the efficacy of the messages in different populations, including smokers with past-month serious psychological distress (SPD), low socioeconomic status (SES), and those in neither category.\n\nThe primary hypothesis is: exposure to messages in combination with VLNC use will lead to less cigarettes use compared to VLNCs without messages.\n\nResearchers will compare: The effects of receiving VLNCs with messages (treatment group) to receiving VLNCs without messages (control group).\n\nParticipants will: Complete a baseline survey and be randomly assigned to one of two groups: treatment (VLNCs + messages) or control (VLNCs only). Attend weekly study visits for surveys, breath samples, and receive supply of VLNCs , either with or without the messaging campaign. Complete brief daily surveys through text messages.",[93,94,95],"Tobacco Products","Smoking Behavior","Cigarette Use",[97,98,99],"smoking","health communication","very low nicotine cigarettes","2025-10-28",{"date":102,"type":103},"2025-10-29","ACTUAL",{"date":105,"type":103},"2025-09-11",{"date":107,"type":87},"2029-01-31",{"name":5,"class":6},2]