[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580290":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":38,"locations":48,"responsibleParty":71,"collaborators":26,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":26,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":26,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":26,"overallStatus":51,"whyStopped":26,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"Asian Institute of Gastroenterology, India","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Assesment of reflux esophagitis in cases with esophageal motility","ACTIVE_COMPARATOR","Reflux esophagitis can be found in Endoscopy report.",[13],"Procedure: Per oral endoscopy myotomy (Per oral endoscopy myotomy)",{"label":15,"type":16,"description":17,"interventionNames":18},"Assesment of reflux esophagitis in cases without esophageal motility","PLACEBO_COMPARATOR","Reflux esophagitis can be found in cases in normal gastroesophageal reflux disease condition patients",[19],"Procedure: Endoscopy procedure",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Per oral endoscopy myotomy (Per oral endoscopy myotomy)","POEM is the procedure to reduce the symptoms of dysphagia, regurgitation.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Endoscopy procedure","Endoscopy procedure is required to rule out type of reflux disease",[15],[32,36],{"name":33,"affiliation":34,"role":35},"Zaheer Nabi Dr Mohammed, MBBS MD","AIG Hospitals","PRINCIPAL_INVESTIGATOR",{"name":37,"affiliation":34,"role":35},"Chinmay Dr Hegde, MBBS MD",[39,45],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Rajesh Goud Mr Maragoni, M.Pharm, MBA","CONTACT","04023378888","531","rajeshgoud761@gmail.com",{"name":33,"role":41,"phone":42,"phoneExt":46,"email":47},"102","zaheernabi1978@gmail.com",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Asian Institute of Gastroenterology Hospital","RECRUITING","Hyderabad","Telangana","500082","India","IN",{"type":58,"coordinates":59},"Point",[60,61],78.45636,17.38405,{"lat":61,"lon":60},[64,68],{"name":65,"role":41,"phone":42,"phoneExt":66,"email":67},"Mohan Ramchandani, MBBS","802","ramchandanimohan@gmail.com",{"name":69,"role":41,"phone":42,"phoneExt":46,"email":70},"Chinmay Hegde, MBBS, MD","chinhegde123@gmail.com",{"type":35,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Mohan Ramchandani","Director","100580290","comparative-assessment-of-esophagitis-in-cases-with-and-without-esophageal-motility-disorders-a-prospective-study-100580290",false,"NCT06835374","Comparative Assessment of Esophagitis in Cases With and Without Esophageal Motility Disorders: A Prospective Study","Comparative Assessment of Reflux Esophagitis in Cases With and Without Esophageal Motility Disorders","Inclusion Criteria:\n\n1. Age≥18y,\n2. confirmed diagnosis of Achalasia,\n3. No contraindication to POEM,\n4. erosive esophagitis on endoscopy\n\nExclusion Criteria:\n\n1. Non-esophageal esophageal motility disorders,\n2. Treatment other than POEM,\n3. current PPI use before assessment for GERD","ALL","18 Years","75 Years",{"count":85,"type":86},200,"ESTIMATED","INTERVENTIONAL",[89],"NA","Achalasia is a neuro-degenerative disorder marked by changes in the peristalsis of the esophagus and the lack of relaxation in the lower esophageal sphincter (LES), thought to be due to damage to the myenteric plexus with an unknown cause.1 Per-oral endoscopic myotomy (POEM) is an established endoscopic treatment modality for achalasia. Leading gastrointestinal (GI) societies endorse POEM as one of the primary treatment option for achalasia.This study aims to characterize and compare the morphological characteristics of reflux related erosions after the POEM procedures versus those in cases without esophageal motility disorders.\n\nData collection\n\n1. Demographic characteristics: Age, gender, type of achalasia\n2. Manometry findings (pre and post POEM): integrated relaxation pressure, lower esophageal sphincter pressure\n3. Comorbidities\n4. Medications\n5. Eckardt score: before procedure and 3-months after Procedure\n6. POEM procedure details: length of esophageal and gastric myotomy, adverse events, length of hospital stay\n7. Evaluation at 3-months Symptom: standardized questionnaire (GERDQ) Endoscopy: grade of esophagitis Erosions vs ulcers Dimension of erosions Anatomical location (according to clock)",[92],"Esophageal Diseases","2026-05-30",{"date":95,"type":96},"2026-06-03","ACTUAL",{"date":98,"type":96},"2024-05-11",{"date":100,"type":86},"2027-05-10",{"name":5,"class":6},1]