[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100477768":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":42,"responsibleParty":60,"collaborators":62,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":26,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":26,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Oregon Health and Science University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of Care","ACTIVE_COMPARATOR","Steroid and lidocaine injection",[13],"Procedure: Nerve block",{"label":15,"type":16,"description":17,"interventionNames":18},"Study","EXPERIMENTAL","Steroid and lidocaine injection with cryoablation",[19],"Device: Cryoablation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Cryoablation","Image (ultrasound and fluoroscopic guided) cryoablation will be performed of the Morton's neuroma after nerve block.",[15],null,{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":26},"PROCEDURE","Nerve block","Ultrasound and fluoroscopic guided nerve block.",[9],[33],{"name":34,"affiliation":5,"role":35},"Claire Kaufman","PRINCIPAL_INVESTIGATOR",[37],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Lori L Russell, MSN BSN RN","CONTACT","503-494-7226","watsonlo@ohsu.edu",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Oregon Health Sciences University","RECRUITING","Portland","Oregon","97239","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-122.67621,45.52345,{"lat":55,"lon":54},[58],{"name":59,"role":39,"phone":26,"phoneExt":26,"email":26},"Lori Russell",{"type":35,"investigatorFullName":34,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Principal Investigator",[63,66],{"name":64,"class":65},"Boston Scientific Corporation","INDUSTRY",{"name":67,"class":6},"Society of Interventional Radiology Foundation","100477768","comparative-effectiveness-of-cryoablation-versus-steroid-and-lidocaine-alone-for-treatment-of-mortons-neuroma-100477768",false,"NCT05501262","Comparative Effectiveness of Cryoablation Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma","Comparative Effectiveness of Cryoablation Using the ICE-Seed Cryoablation Needle With Steroid and Lidocaine Versus Steroid and Lidocaine Alone for Treatment of Morton's Neuroma","Inclusion Criteria:\n\n* Age \\>18 years\n* Able to consent and complete questionnaires\n* Failure of a four-week trial of conservative therapy (includes orthotics, appropriate footwear, and\u002For metatarsal pads)\n* X-ray and ultrasound excluding other pathology and confirming the presence and location of a Morton's neuroma\n\nExclusion Criteria:\n\n* Inability to follow-up or to comply with the follow-up protocol\n* Contraindication to cryoablation and\u002For lidocaine\u002Fsteroid injection\n* Other pathology which could account for symptoms identified on imaging studies\n* Unwillingness to be randomized",true,"ALL","18 Years","105 Years",{"count":80,"type":81},32,"ESTIMATED","INTERVENTIONAL",[84],"NA","Morton's neuroma is a benign thickening involving the plantar interdigital nerve, most common in middle aged women. Morton's neuroma is one of the most frequent diagnoses seen in the investigators podiatry clinic and is difficult to treat. These lesions cause a burning or shooting pain that can radiate to the toes, or an aching pain in the ball of the foot. The pain is exacerbated with activity and certain footwear greatly limits activity in the involved patient population. Morton's neuroma is first treated conservatively with orthotics. Patients may require further interventions such as steroid injections. The literature reports only a 30% long term resolution of pain with the steroid. Surgical resection has a reported 51-85% success rate with 14-21% rate of complication; recurrent pain, numbness\u002Floss of sensation, and subsequent stump neuromas.\n\nCryoablation is well known to be efficacious for neuropathic pain and has recently been shown in two small studies to be safe and efficacious for treatment of Morton's neuroma. The investigators study will compare outcomes of cryoablation to corticosteroid injection in short- and long-term for treatment of Morton's neuroma that have failed conservative therapy.",[87],"Morton Neuroma","2025-10-14",{"date":90,"type":91},"2025-10-16","ACTUAL",{"date":93,"type":91},"2022-07-25",{"date":95,"type":81},"2027-12-31",{"name":5,"class":6},1]