[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637264":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":61,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":66,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Ibadat International University, Islamabad","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"BFR Resistance Training Group","ACTIVE_COMPARATOR","Participants perform leg press and seated knee extension exercises at 30% of 1RM with a pneumatic cuff (12 cm wide, Delfi Medical) applied to the proximal thigh at 80% limb occlusion pressure (LOP). Protocol: 1 set of 30 + 3 sets of 15 repetitions, with 60-second rest between sets (cuff deflated). Frequency: 3 sessions\u002Fweek for 8 weeks (24 sessions total). 1RM re-estimated every 2 weeks for progressive load adjustment. Warm-up: 10 min low-resistance cycling (no BFR). Cool-down: 5 min lower-limb stretching.",[13],"Device: Blood Flow Restriction Resistance Training",{"label":15,"type":16,"description":17,"interventionNames":18},"BFR Cycling Group","EXPERIMENTAL","Participants perform stationary cycling at low resistance targeting RPE 11-13, with a pneumatic cuff (12 cm wide, Delfi Medical) applied to the proximal thigh at 80% LOP. Protocol: 4 x 5-minute cycling intervals at 70-80 RPM, with 1-minute rest between intervals (cuff deflated). Frequency: 3 sessions\u002Fweek for 8 weeks (24 sessions total). Cadence increased by 5 RPM if RPE \\\u003C11. Warm-up: 10 min low-resistance cycling (no BFR). Cool-down: 5 min lower-limb stretching.",[19],"Device: Blood Flow Restriction Cycling",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Blood Flow Restriction Resistance Training","Participants will undergo blood flow restriction (BFR) resistance training using a pneumatic cuff applied to the proximal thigh at 80% limb occlusion pressure. Exercises include leg press and seated knee extension performed at 30% of one-repetition maximum (1RM). Training will be conducted for 8 weeks, with supervised sessions 3 times per week. Cuff pressure will be monitored and adjusted using BP cuff. The aim is to improve quadriceps strength and reduce pain in patients with patellofemoral pain.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Blood Flow Restriction Cycling","Participants will perform stationary cycling combined with blood flow restriction (BFR) applied to the proximal thigh at 80% limb occlusion pressure. Cycling will be performed at low resistance with controlled cadence for 8 weeks, 3 sessions per week under physiotherapist supervision. The protocol includes structured cycling intervals with rest periods and continuous monitoring of pain and perceived exertion. The intervention aims to improve quadriceps strength, reduce pain, and enhance functional outcomes in patients with patellofemoral pain.",[15],[32],{"name":33,"affiliation":34,"role":35},"Hafsah Gul Khattak, DPT, MS-NMPT","IBADAT INTERNATIONAL UNIVERSITY, ISLAMABAD (IIUI)","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":26,"email":41},"Haroon Khan, MS. Sports Physical Therapy","CONTACT","+923000526711","haroonkhan2k00@gmail.com",{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},"923457170732","hafsahgull_khattak@yahoo.com",[46],{"facility":47,"status":48,"city":49,"state":26,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Ibadat International University, Islamabad (Iiui)","RECRUITING","Islamabad","46000","Pakistan","PK",{"type":54,"coordinates":55},"Point",[56,57],73.04329,33.72148,{"lat":57,"lon":56},[60],{"name":33,"role":39,"phone":43,"phoneExt":26,"email":44},{"type":35,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Hafsah Gul Khattak","Assistant Professor","100637264","comparative-effects-of-blood-flow-restriction-resistance-training-versus-blood-flow-restriction-cycling-on-pain-quadriceps-strength-and-functional-outcomes-in-athletes-with-patellofemoral-pain-100637264",false,"NCT07585305","Comparative Effects of Blood Flow Restriction Resistance Training Versus Blood Flow Restriction Cycling on Pain, Quadriceps Strength, and Functional Outcomes in Athletes With Patellofemoral Pain","Comparative Effects of Blood Flow Restriction Resistance Training Versus Blood Flow Restriction Cycling on Pain, Quadriceps Strength, and Functional Outcomes in Athletes With Patellofemoral Pain: A Randomized Controlled Trial","BFR-PFP-RCT","Inclusion Criteria:\n\n1. Male and female athletes aged 18-40 years\n2. Clinically diagnosed with patellofemoral pain syndrome\n3. Anterior or retropatellar knee pain of at least 3 months duration\n4. Pain provoked by at least two functional activities (e.g., squatting, stair climbing, running, prolonged sitting)\n5. Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n1. History of knee surgery or significant knee trauma in the past 6 months\n2. Presence of ligament, meniscal, or cartilage injuries\n3. Neurological, vascular, or systemic inflammatory conditions\n4. Contraindications to BFR training (e.g., deep vein thrombosis, uncontrolled hypertension)\n5. Pregnancy","ALL","18 Years","40 Years",{"count":76,"type":77},48,"ESTIMATED","INTERVENTIONAL",[80],"NA","This randomized controlled trial compares blood flow restriction (BFR) resistance training (leg press and seated knee extension at 30% 1RM) versus BFR cycling (stationary cycling at low resistance) in 60 athletes (aged 18-40 years) diagnosed with patellofemoral pain syndrome. Both interventions are delivered over 8 weeks (3 sessions\u002Fweek) with a pneumatic cuff set at 80% limb occlusion pressure. Primary outcomes include pain intensity (NPRS), quadriceps strength (handheld dynamometer), and functional ability (Kujala Anterior Knee Pain Scale), assessed at baseline and post-intervention.",[83],"Patello Femoral Pain Syndrome",[85,86,87,88,89],"Patellofemoral pain","Blood flow restriction training","Quadriceps strength","Athletic Performance","resistance training","2026-06-23",{"date":92,"type":93},"2026-06-26","ACTUAL",{"date":95,"type":93},"2026-05-10",{"date":97,"type":77},"2026-07-25",{"name":5,"class":6},1]