[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607543":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":60,"collaborators":63,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":26,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":26,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":93,"whyStopped":26,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},{"fullName":5,"class":6},"Dr. Sirajul Islam Medical College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Ablative fractional CO2 laser","ACTIVE_COMPARATOR","Participants will receive ablative fractional CO₂ laser therapy on one side of the face using the SmartXide DOT Fractionated CO₂ Laser system. Treatment parameters include 15 W power, 800 µm spacing, 600 µs dwell time, and stack level 2. A total of three sessions will be administered, each one month apart.",[13],"Procedure: Ablative Fractional CO₂ Laser",{"label":15,"type":16,"description":17,"interventionNames":18},"Platelet-Rich Plasma (PRP) With Microneedling","EXPERIMENTAL","Participants will receive intradermal injections of autologous PRP followed by microneedling on the opposite side of the face. PRP will be prepared using a double-spin centrifugation method from 8 mL of venous blood. Microneedling will be performed with a Dermapen (12-needle cartridge, 1.5 mm depth) until pinpoint bleeding is observed. A total of three sessions will be administered, each one month apart.",[19],"Procedure: Platelet-Rich Plasma (PRP) With Microneedling",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ablative Fractional CO₂ Laser","Participants will receive ablative fractional CO₂ laser therapy on one side of the face using the SmartXide DOT Fractionated CO₂ Laser system. Treatment parameters: 15 W power, 800 µm spacing, 600 µs dwell time, stack level 2. Sessions: 3, each one month apart.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Participants will receive intradermal autologous PRP injections prepared by double-spin centrifugation from 8 mL of venous blood, followed by microneedling with a Dermapen (12-needle cartridge, 1.5 mm depth). Endpoint: pinpoint bleeding. Sessions: 3, each one month apart.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Mohammad Jahid Hasan, MBBS, MPH","CONTACT","+8801767818973","dr.jahid61@gmail.com",{"name":37,"role":33,"phone":38,"phoneExt":26,"email":39},"Tamanna Tabassum, MBBS, MPH","+8801755383138","dr.tabassum1991@gmail.com",[41],{"facility":42,"status":26,"city":43,"state":26,"zip":26,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Dhala Medical College","Dhaka","Bangladesh","BD",{"type":47,"coordinates":48},"Point",[49,50],90.40744,23.7104,{"lat":50,"lon":49},[53,57],{"name":54,"role":33,"phone":55,"phoneExt":26,"email":56},"Md. Mohiuddin Sharif","+8801717539682","mohiuddinsharif.fmc@gmail.com",{"name":58,"role":59,"phone":26,"phoneExt":26,"email":26},"Fahmida Zebin","PRINCIPAL_INVESTIGATOR",{"type":59,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Azmiree Binte Aslam","Assistant Professor, Department of Dermatology and Venereology",[64],{"name":65,"class":6},"Dhaka Medical College","100607543","comparative-real-world-study-on-ablative-fractional-co-laser-vs-prp-with-microneedling-for-acne-scar-treatment-100607543",false,"NCT07189923","Comparative Real-world Study on Ablative Fractional CO₂ Laser vs PRP With Microneedling for Acne Scar Treatment.","Efficacy and Safety of Ablative Fractional CO2 Laser and Platelet-rich Plasma (PRP) With Microneedling for Treatment of Acne Scars: a Real-world Comparative Study","Inclusion Criteria:\n\n* Adult patients (age \\>18 years)\n* Both male and female sex\n* Patients with grade 2 to grade 4 acne scars, classified on the basis of Goodman's Qualitative classification.\n* Patient with equal Goodman's Qualitative scores on both halves of the face.\n* No active acne lesions.\n* Patients with atrophic scars only.\n\nExclusion Criteria:\n\n* Positive history of keloidal tendency.\n* Positive history of bleeding or platelet disorder.\n* Positive history of major surgery in past 6 months.\n* Presence of any acute infection on face like, herpes, folliculitis.\n* Patients of HIV, HBsAg, or any chronic illness.\n* Pregnancy","ALL","18 Years",{"count":76,"type":77},116,"ESTIMATED","INTERVENTIONAL",[80],"NA","Road traffic accidents (RTAs) remain a major public health concern worldwide and in Bangladesh, contributing significantly to injury, disability, and premature death. In resource limited settings like Bangladesh, it is crucial to understand the factors that influence survival following an RTA in order to develop effective prevention strategies and improve patient outcomes. Therefore, this study aims to determine the 30 day survival rate and identify predictors of survival among adult RTA victims treated at a tertiary care hospital in Bangladesh. The observational study will be carried out at Emergency and casualty department of Dhaka Medical College Hospital (DMCH) between October 2025 and March 2026. A total of 204 adults (≥18 years) presenting to the hospital's Casualty Department with RTA related injuries will be included. Informed written consent will be obtained from each patient or their legal guardian prior to enrollment. Data will be collected through structured face to face interviews, review of hospital records, and follow up on the 30th day of accident. The follow-up will be conducted either in person or by telephone. Variables will include patient demographics, accident circumstances, admission characteristics, injury pattern and severity, pre-hospital care, clinical condition at admission, hospital management provided, and treatment outcome. All data will be analyzed using SPSS version 25.0. Kaplan-Meier analysis will estimate survival probabilities, while Cox proportional hazards regression will be used to identify independent predictors of mortality. The findings of this study are expected to generate context-specific, evidence-based insights for strengthening trauma care protocols, gap related to emergency handling of the RTA patients, enhancing pre-hospital emergency services, and informing policy decisions aimed at reducing preventable RTA-related mortality and morbidity in Bangladesh.",[83,84,85],"Acne Scars","Ablative Fractional CO₂ Laser Therapy","Platelet-rich Plasma (PRP)",[83,87,88,89,90,91,44,92],"Ablative fractional CO₂ laser therapy","Platelet-rich plasma (PRP)","Microneedling","Efficacy","Safety","Goodman and Baron scale","NOT_YET_RECRUITING","2025-12-02",{"date":96,"type":97},"2025-12-03","ACTUAL",{"date":99,"type":77},"2025-12-01",{"date":101,"type":77},"2026-11-30",{"name":5,"class":6},1]