[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600471":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":24,"locations":24,"responsibleParty":29,"collaborators":24,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":35,"acronym":24,"eligibilityCriteria":36,"healthyVolunteers":33,"sex":37,"minAge":38,"maxAge":39,"enrollmentInfo":40,"targetDuration":24,"studyType":43,"phases":44,"briefSummary":46,"conditions":47,"keywords":24,"overallStatus":49,"whyStopped":24,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":55,"leadSponsor":57,"locationsCount":24},{"fullName":5,"class":6},"He Eye Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Study group","EXPERIMENTAL","dry eye patients after LASIK",[13],"Drug: 3% Diquafosol Sodium Eye Drops",{"label":15,"type":6,"description":11,"interventionNames":16},"Control group",[17],"Drug: 0.1% hyaluronic acid",[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DRUG","3% Diquafosol Sodium Eye Drops","3% Diquafosol Sodium Eye Drops were instilled into the inferior conjunctival vault of both eyes",[9],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"0.1% hyaluronic acid","0.1% sodium hyaluronate eye drops were instillation into the inferior conjunctival vault of both eyes",[15],{"type":30,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100600471","compare-the-clinical-efficacy-of-3-diquafosol-and-01-hyaluronic-acid-in-patients-with-dry-eye-after-lasik-100600471",false,"NCT07097922","Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients With Dry Eye After LASIK","Inclusion Criteria:\n\n* History of LASIK surgery for more than six months\n* Confirmed dry eye: patients complained of one of the subjective symptoms of ocular dryness, foreign body sensation, burning sensation, fatigue, discomfort, redness of the eyes, and fluctuating visual acuity; as well as (a) OSDI questionnaire score of ≥13 and (b) non-invasive tear break-up time (NITBUT) of \\\u003C10 s or (c) ocular surface staining assessed in \\>5 corneal patches\u002Fgreater than 9 conjunctival patches\n* Participants were able to co-operate with the use of eye drops as required, complete the examination, and return to the hospital within the specified time for follow-up examinations to complete the follow-up visit.\n\nExclusion Criteria:\n\n* Suspected of having keratoconus, a definite diagnosis of keratoconus or another type of corneal dilatation disease.\n* There is active inflammation or symptoms of infection in the eye\n* There are serious lesions in the accessory structures of the eye, such as defects or deformations of the eyelids\n* Patients with Connective tissue diseases and Autoimmune disorders (e.g., SLE, RA)","ALL","18 Years","40 Years",{"count":41,"type":42},140,"ESTIMATED","INTERVENTIONAL",[45],"NA","The prevalence of refractive ametropia is rising year by year. Refractive surgery has become the main approach for adults to correct refractive ametropia, and postoperative complications have aroused extensive attention from clinicians. Dry eye after refractive surgery is one of the postoperative complications, which is an important cause of affecting the postoperative visual quality and satisfaction of patients. It was reported that 3% diquafosol (DQS) and 0.1% hyaluronic acid (HA) can relieve dry eye symptoms. This study aims to compare the efficacy of 3% DQS and 0.1% HA in treating dry eye after LASIK",[48],"Dry Eye","NOT_YET_RECRUITING","2025-07-30",{"date":52,"type":53},"2025-08-01","ACTUAL",{"date":52,"type":42},{"date":56,"type":42},"2026-05-01",{"name":5,"class":6}]