[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595811":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":55,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":83,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Chungbuk National University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Cycle of Breathing Technique (ACBT) group","ACTIVE_COMPARATOR","patients with bronchiectasis using ACBT",[13],"Device: Active Cycle of Breathing Technique (ACBT) group",{"label":15,"type":16,"description":17,"interventionNames":18},"Active Cycle of Breathing Technique (ACBT) and Oscillatory Positive Expiratory Pressure (OPEP) group","EXPERIMENTAL","Patients with bronchiectasis using ACBT and OPEP simultaneously",[19],"Device: Active Cycle of Breathing Technique (ACBT) and Oscillatory Positive Expiratory Pressure (OPEP) group",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Patients with bronchiectasis using ACT and OPEP simultaneously",[15],null,{"type":22,"name":9,"description":27,"armGroupLabels":28,"otherNames":25},"Patients will receive only ACBT for airway clearance.",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Bumhee Yang, MD, PhD","CONTACT","+82 43-269-8210","ybhworld0415@gmail.com",[36],{"facility":5,"status":25,"city":37,"state":38,"zip":39,"country":40,"countryCode":25,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Cheongju-si","North Chungcheong","28644","South Korea",{"type":42,"coordinates":43},"Point",[44,45],127.48972,36.63722,{"lat":45,"lon":44},[48,50],{"name":31,"role":32,"phone":49,"phoneExt":25,"email":34},"+82-43-269-8210",{"name":31,"role":51,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":51,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Bumhee Yang, MD","Associate professor",[56],{"name":57,"class":58},"Trudell Medical International","INDUSTRY","100595811","comparing-active-cycle-of-breathing-techniques-acbt-and-aerobika-in-treating-bronchiectasis-in-korea-100595811",false,"NCT07037303","Comparing Active Cycle of Breathing Techniques (ACBT) and Aerobika in Treating Bronchiectasis in Korea","Comparison of Effectiveness Between Active Cycle of Breathing Techniques (ACBT) and Oscillating Positive Expiratory Pressure (OPEP, Aerobika) Device Assisted Treatment in Patients With Bronchiectasis in Korea : Randomized Controlled Trials","Inclusion Criteria:\n\n* 18 years of age or older\n* Patients diagnosed with bronchiectasis involving one or more lobes on chest computed tomography (CT)\n* Patients experiencing frequent exacerbations (3 or more exacerbations) within 1 year\n* Patients able and willing to use the Aerobika device (OPEP)\n\nExclusion Criteria:\n\n* Diagnosis of bronchiectasis due to cystic fibrosis\n* Traction bronchiectasis due to interstitial lung disease (ILD)\n* Pregnant patients\n* Patients with a history of OPEP device use\n* Patients who cannot tolerate increased breathing work\n* Hemodynamic instability (e.g., unstable blood pressure)\n* Patients with a past or current history of hemoptysis (pulmonary bleeding) and untreated pneumothorax",true,"ALL","18 Years",{"count":70,"type":71},100,"ESTIMATED","INTERVENTIONAL",[74],"NA","Title:\n\nComparison of Effectiveness Between Active Cycle of Breathing Techniques (ACBT) and Oscillating Positive Expiratory Pressure (OPEP, Aerobika) Device Assisted Treatment in Patients With Bronchiectasis in Korea: A Randomized Controlled Trial\n\nPurpose:\n\nThis study aims to evaluate the effectiveness of Active Cycle of Breathing Techniques (ACBT) alone versus ACBT combined with an Oscillating Positive Expiratory Pressure (OPEP) device (Aerobika) in patients with bronchiectasis. The goal is to determine whether the combination therapy reduces the frequency of acute exacerbations and improves patient symptoms compared to ACBT alone.\n\nPrimary Questions:\n\nDoes the use of ACBT plus Aerobika reduce the number of acute exacerbations in patients with bronchiectasis who experience ≥3 exacerbations per year?\n\nWhat symptoms and adverse events are observed in participants using the Aerobika device?\n\nStudy Design:\n\nThis is a single-center, randomized, controlled clinical trial conducted at Chungbuk National University Hospital in Korea. 100 adult patients diagnosed with bronchiectasis and having ≥3 acute exacerbations within 1 year will be enrolled and randomized into two groups (1:1):\n\nActive Cycle of Breathing Technique (ACBT) group\n\nActive Cycle of Breathing Technique (ACBT) and Oscillatory Positive Expiratory Pressure (OPEP) group\n\nThe intervention period lasts 12 months, with clinic visits scheduled at 0, 1, 3, 6, 9, and 12 months.\n\nParticipation Involves:\n\nUse of ACBT with or without Aerobika daily for 12 months\n\nIn-person clinic visits every 1 to 3 months\n\nMonthly phone follow-ups to assess symptoms and adverse events\n\nCompletion of questionnaires (mMRC, BHQ, CAT) and clinical tests including PFT and laboratory tests\n\nTracking of exacerbation frequency, sputum volume, and quality",[77,78],"Bronchiectasis","Bronchiectasis With Acute Exacerbation",[80,81,82],"bronchiectasis","aerobika","ACBT","NOT_YET_RECRUITING","2025-06-21",{"date":86,"type":87},"2025-06-25","ACTUAL",{"date":89,"type":71},"2025-07-01",{"date":91,"type":71},"2028-07-01",{"name":5,"class":6},1]