[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595253":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":37,"collaborators":39,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":26,"enrollmentInfo":53,"targetDuration":26,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":66,"whyStopped":26,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":26},{"fullName":5,"class":6},"Clinique Trenel","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PS-group","EXPERIMENTAL","Individualized PS TKA",[13],"Device: Postero-stabilized total knee replacement for knee osteoarthritis",{"label":15,"type":16,"description":17,"interventionNames":18},"CR-group","ACTIVE_COMPARATOR","Individualized CR TKA",[19],"Device: Cruciate-retaining total knee replacement for knee osteoarthritis",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Postero-stabilized total knee replacement for knee osteoarthritis","Total knee arthroplasty in which the osteoarthritic knee is replaced with a postero-stabilized total knee replacement. The postero-stabilized TKA consists of a femoral component with a build-in cam mechanism and a tibial component with a post-mechanism.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Cruciate-retaining total knee replacement for knee osteoarthritis","Total knee arthroplasty in which the osteoarthritic knee is replaced with a cruciate-retaining total knee replacement. The cruciate-retaining TKA consists of a femoral component and a tibial component that leaves the posterior cruciate ligament intact.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Johanne Beuvelot Beuvelot, PhD","CONTACT","0033 67623373","johanne.beuvelot@clinique-trenel.com",{"type":38,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[40],{"name":41,"class":42},"ProSurg","UNKNOWN","100595253","comparing-articular-noise-and-its-perception-between-two-different-types-of-individualized-total-knee-arthroplasty-100595253",false,"NCT07030049","Comparing Articular Noise and Its Perception Between Two Different Types of Individualized Total Knee Arthroplasty","Monocentric, Randomized Study, Comparing Articular Noise and Its Perception Between Two Different Types of Individualized Total Knee Arthroplasty","ANIKA","Inclusion Criteria:\n\nAdult patients:\n\n* receiving elective primary TKA as a treatment for osteoarthritis\n* with an intact and functional posterior cruciate ligament\n* with no previous knee surgery, on the ipsi- or contra-lateral knee\n* who signed the informed consent and are willing to comply with the protocol requirements based on the investigator's judgment.\n* affiliated with a social security scheme\n* with an ability to answer questionnaires and to communicate freely in French.\n\nExclusion Criteria:\n\nPatients:\n\n* that underwent previous knee surgery, except arthroscopic surgery, on their ipsilateral knee\n* with coronal deformities \\>20°\n* that are pregnant\n* any contraindication mentioned in the instructions for use of the medical devices under investigation\n* with protected status under articles L1121-6, LL121-8 and L1122-2 of the French Public Health Code\n* with other significant disease or disorder which, in the opinion of the investigating surgeon, may put the participant at risk because of participation in the study, or may influence the result of the study\n* who cannot comply with the protocol requirements based on the investigator's judgment.","ALL","18 Years",{"count":54,"type":55},210,"ESTIMATED","INTERVENTIONAL",[58],"NA","Knee osteoarthritis is a degenerative joint disorder leading to pain and limited movement. Total knee arthroplasty (TKA) has transformed the treatment of knee osteoarthritis, resulting in long-term outcomes that enhance the quality of life for patients. Some individuals report experiencing noise after undergoing TKA. However, there are few randomized controlled trials that assess postoperative noise following the procedure. Additionally, no research has been conducted on individualized TKA, which involves custom-made prostheses tailored to a patient's knee shape. This study aimed to compare the incidence of noise reported by patients who undergo a primary individualized TKA using either cruciate-retaining or posterior-stabilized designs.",[61,62],"Osteoarthritis","TKA",[64,62,65],"osteoarthritis","articular noise","NOT_YET_RECRUITING","2025-06-23",{"date":69,"type":70},"2025-06-26","ACTUAL",{"date":72,"type":55},"2025-09-30",{"date":74,"type":55},"2028-09-30",{"name":5,"class":6}]