[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584419":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":29,"locations":26,"responsibleParty":35,"collaborators":26,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":41,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":26,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":26,"overallStatus":59,"whyStopped":26,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":26},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"opioid sparing","ACTIVE_COMPARATOR","two syringes of lidocaine 10 mg\u002FmL will be prepared. A 10-mL syringe (induction syringe) will be given during the induction of anesthesia and A 50 mL syringe (infusion syringe) will be used as continuous infusion.",[13],"Drug: : two syringes of lidocaine 10 mg\u002FmL will be prepared. A 10-mL syringe (induction syringe) will be given during the induction of anesthesia and A 50 mL syringe (infusion syringe) will be used as conti",{"label":15,"type":16,"description":17,"interventionNames":18},"conventional","PLACEBO_COMPARATOR","A 10-mL syringe of 10 mcg\u002FmL fentanyl (induction syringe) and a 50-mL syringe of saline (infusion syringe) will be prepared as placebo.",[19],"Drug: A 10-mL syringe of 10 mcg\u002FmL fentanyl (induction syringe) and a 50-mL syringe of saline (infusion syringe) will be prepared as placebo.",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG",": two syringes of lidocaine 10 mg\u002FmL will be prepared. A 10-mL syringe (induction syringe) will be given during the induction of anesthesia and A 50 mL syringe (infusion syringe) will be used as conti",": two syringes of lidocaine 10 mg\u002FmL will be prepared. A 10-mL syringe (induction syringe) will be given during the induction of anesthesia and A 50 mL syringe (infusion syringe) will be used as continuous infusion.",[9],null,{"type":22,"name":17,"description":17,"armGroupLabels":28,"otherNames":26},[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":26,"email":34},"Mai Madkour, Associate professor","CONTACT","+201223657694","maimadkour@kasralainy.edu.eg",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Mai Madkour","Associate professor","100584419","comparing-effect-of-opioid-sparing-versus-conventional-anesthesia-on-quality-of-recovery-after-emergency-laparotomy-100584419",false,"NCT06889090","Comparing Effect of Opioid-sparing Versus Conventional Anesthesia on Quality of Recovery After Emergency Laparotomy","Comparing Effect of Opioid-sparing Versus Conventional Anesthesia on Quality of Recovery After Emergency Laparotomy: a Randomized Controlled Trial","O-S Anesthesia","Inclusion Criteria:\n\n* Adult patients (18-65 years)\n* ASA I-III undergoing emergency laparotomy with midline incision.\n\nExclusion Criteria:\n\n* Severe cardiac morbidities (impaired contractility with ejection fraction \\\u003C 45%, heart block, arrhythmias, tight valvular lesions) and patients on beta-blockers\n* Patients on vasopressor infusion, patients with high shock index (heart rate \u002F systolic blood pressure \\>1)\n* Body mass index \\\u003C18 or \\> 35 Kg\u002Fm2,\n\n  * Pregnant or lactating women,","ALL","18 Years","65 Years",{"count":51,"type":52},120,"ESTIMATED","INTERVENTIONAL",[55],"NA","Aim of the Work The investigators aim to compare lidocaine-based anesthesia versus conventional anesthesia in the presence of multimodal analgesia protocol in terms of early quality of recovery and analgesic efficacy.\n\nObjectives To compare quality of recovery using the Quality of recovery-15 (QoR-15) score between lidocaine-based anesthesia in relation to conventional anesthesia in patients undergoing emergency laparotomy.\n\nHypothesis the investigators hypothesize that lidocaine-based regimen would be effective in reducing opioid use and provide superior quality of recovery compared to conventional opioid-routine anesthesia in emergency laparotomy.",[58],"Anesthesia Recovery Period","NOT_YET_RECRUITING","2025-03-21",{"date":62,"type":63},"2025-03-26","ACTUAL",{"date":65,"type":52},"2025-04-20",{"date":67,"type":52},"2026-05-12",{"name":5,"class":6}]