[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574589":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":29,"locations":36,"responsibleParty":47,"collaborators":34,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":34,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":74,"overallStatus":80,"whyStopped":34,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Fluorescent Starch Nanoparticles Rinse for Caries Detection","EXPERIMENTAL","Participants in this arm will undergo diagnostic evaluation using the fluorescent starch nanoparticles caries detection rinse. The rinse contains fluorescent starch nanoparticles that infiltrate porous enamel in active caries lesions. After application, a dental curing light will be used to activate fluorescence, allowing clinicians to identify and differentiate active caries from inactive lesions and other conditions like hypomineralization.\n\nThe performance of the rinse will be compared to the International Caries Detection and Assessment System (ICDAS), which serves as the reference standard for evaluating early dental caries. Data on sensitivity, specificity, and diagnostic accuracy will be collected for analysis.",[13],"Device: Fluorescent Starch Nanoparticles Caries Detection Rinse",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Fluorescent Starch Nanoparticles Caries Detection Rinse","The fluorescent starch nanoparticles caries detection rinse is an innovative diagnostic tool designed to enhance the early detection of active dental caries. It contains proprietary fluorescent starch nanoparticles that infiltrate the porous enamel of active caries lesions. Upon illumination with a standard dental curing light, the nanoparticles fluoresce, allowing clinicians to differentiate active caries from inactive lesions and other enamel conditions. This rinse is evaluated as a non-invasive, highly sensitive, and specific diagnostic device.",[9],[21],"LumiKids™ Rinse GreenMark Biomedical",[23,26],{"name":24,"affiliation":5,"role":25},"Associate Prof. Dr. Mariam Mohsen aly, Ph.D.","STUDY_DIRECTOR",{"name":27,"affiliation":5,"role":28},"Dr. Reem Mohamed Fouad Wahby, Ph.D.","STUDY_CHAIR",[30],{"name":31,"role":32,"phone":33,"phoneExt":34,"email":35},"Omar Kamel Salem Eshbair, Bachelor of Dental Science","CONTACT","+201148899948",null,"omarksse@gmail.com",[37],{"facility":38,"status":34,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":34,"geoPoint":34,"contacts":44},"Faculty of Dentistry, Cairo University","Cairo","Giza Governorate","12613","Egypt","EG",[45],{"name":46,"role":32,"phone":33,"phoneExt":34,"email":35},"Omar Kamel salem Eshbair, B.D.Sc.",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":34,"oldOrganization":34},"PRINCIPAL_INVESTIGATOR","Omar kamel salem Eshbair","Doctor","100574589","comparing-fluorescent-starch-nanoparticles-rinse-with-icdas-for-early-caries-detection-in-children-100574589",false,"NCT06761248","Comparing Fluorescent Starch Nanoparticles Rinse with ICDAS for Early Caries Detection in Children","Clinical Effectiveness of Fluorescent Starch Nanoparticles Caries Detection Rinse Versus International Caries Detection and Assessment System for Detection of Early Dental Caries in Children: a Diagnostic Accuracy Study","FSNCDR-ICDAS","Inclusion Criteria:\n\n* Children with active initial caries.\n* At least two teeth with active caries (ICDAS 1 or 2) and two teeth with inactive caries.\n\nExclusion Criteria:\n\n* Teeth with hypoplasia, fractures, or conditions like dentinogenesis imperfecta.\n* Children with fixed orthodontic appliances.\n* Participants whose guardians refuse consent.","ALL","6 Years","11 Years",{"count":63,"type":64},78,"ESTIMATED","INTERVENTIONAL",[67],"NA","The present study aims to evaluate the diagnostic accuracy of fluorescent starch nanoparticles caries detection rinse versus the International Caries Detection and Assessment System (ICDAS) in identifying early dental caries among children from 6 to 11 years old.",[70,71,72,73],"Dental Caries","Detection","Fluorescence","Diagnostic Accuracy",[75,76,77,78,79],"Fluorescence-Based Caries Detection","Caries Detection Rinse","Early Caries Detection","ICDAS","FSN","NOT_YET_RECRUITING","2024-12-31",{"date":83,"type":84},"2025-01-07","ACTUAL",{"date":86,"type":64},"2025-03-10",{"date":88,"type":64},"2026-08-15",{"name":5,"class":6},1]