[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586536":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":51,"locations":60,"responsibleParty":78,"collaborators":36,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":36,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":36,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":36,"overallStatus":63,"whyStopped":36,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Al Hayah University In Cairo","OTHER",[8,15,21,26],{"label":9,"type":10,"description":11,"interventionNames":12},"HILT + Standard Exercise","EXPERIMENTAL","Participants receive High-Intensity Laser Therapy (HILT) 2 times\u002Fweek for 6 weeks, plus the Standard Exercise Program.",[13,14],"Device: High-Intensity Laser Therapy (HILT)","Behavioral: Standard Exercise Program",{"label":16,"type":17,"description":18,"interventionNames":19},"Corticosteroid Injection + Standard Exercise","ACTIVE_COMPARATOR","Participants receive a single ultrasound-guided intra-articular corticosteroid injection at baseline, plus the Standard Exercise Program.",[20,14],"Drug: Ultrasound-Guided Intra-articular Corticosteroid Injection",{"label":22,"type":17,"description":23,"interventionNames":24},"Manual Therapy + Standard Exercise","Participants receive manual therapy 2 times\u002Fweek for 6 weeks, plus the Standard Exercise Program.",[25,14],"Behavioral: Manual Therapy",{"label":27,"type":17,"description":28,"interventionNames":29},"Standard Exercise Alone","Participants receive the Standard Exercise Program only.",[14],[31,37,42,47],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DEVICE","High-Intensity Laser Therapy (HILT)","Nd:YAG laser (1064 nm) applied to anterior, lateral, posterior glenohumeral joint aspects. Three-phase protocol per session: (1) 10 J\u002Fcm² @ 10 Hz; (2) 12 J\u002Fcm² @ 2000 Hz; (3) 10 J\u002Fcm² @ 15 Hz. Total energy \\~1200 J\u002Fsession. Frequency: 2 sessions\u002Fweek for 6 weeks (12 sessions total). Delivered by trained PTs.",[9],null,{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":36},"DRUG","Ultrasound-Guided Intra-articular Corticosteroid Injection","Single injection into the glenohumeral joint under ultrasound guidance. Consists of 40 mg methylprednisolone acetate combined with 4 ml of 1% lidocaine hydrochloride. Delivered at baseline by an experienced orthopedic physician.",[16],{"type":43,"name":44,"description":45,"armGroupLabels":46,"otherNames":36},"BEHAVIORAL","Manual Therapy","Skilled hands-on techniques including glenohumeral joint mobilizations (Maitland grades III-IV), posterior capsule stretching, scapular mobilization, and soft tissue techniques targeting restricted tissues. Session duration: \\~30 minutes. Frequency: 2 sessions\u002Fweek for 6 weeks (12 sessions total). Delivered by PTs specialized in manual therapy.",[22],{"type":43,"name":48,"description":49,"armGroupLabels":50,"otherNames":36},"Standard Exercise Program","Standardized program including pendulum exercises, active-assisted range of motion exercises (e.g., wand, wall climbs), stretching (e.g., cross-body, sleeper stretch), and progressive resistive exercises using resistance bands. Includes supervised instruction\u002Fprogression and a daily home exercise program component. Supervised instruction frequency: 2 sessions\u002Fweek for first 6 weeks, then 1 session\u002Fweek for next 6 weeks (total 18 supervised sessions over 12 weeks). Delivered by trained PTs.",[16,9,22,27],[52,57],{"name":53,"role":54,"phone":55,"phoneExt":36,"email":56},"Ibrahim Zoheiry, Ph.D","CONTACT","01277774949","ibrahim.alzoheiry@hotmail.com",{"name":58,"role":54,"phone":36,"phoneExt":36,"email":59},"Mohamed ElMeligie, Ph.D","mohamed.elmeligie@ahuc.edu.eg",[61],{"facility":62,"status":63,"city":64,"state":36,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Faculty of Physical Therapy, Al Hayah University","RECRUITING","Cairo","12311","Egypt","EG",{"type":69,"coordinates":70},"Point",[71,72],31.24967,30.06263,{"lat":72,"lon":71},[75],{"name":58,"role":54,"phone":76,"phoneExt":77,"email":59},"01159880001","+20",{"type":79,"investigatorFullName":36,"investigatorTitle":36,"investigatorAffiliation":36,"oldNameTitle":36,"oldOrganization":36},"SPONSOR","100586536","comparing-hilt-steroid-injection-and-manual-therapy-for-frozen-shoulder-100586536",false,"NCT06916650","Comparing HILT, Steroid Injection, and Manual Therapy for Frozen Shoulder","Comparative Effectiveness of High-Intensity Laser Therapy Versus Corticosteroid Injection Versus Manual Therapy, Each Combined With Standard Exercise, for Frozen Shoulder (Adhesive Capsulitis): A Randomized Controlled Trial","Inclusion Criteria:\n\nAge between 40 and 70 years, inclusive. Clinical diagnosis of primary (idiopathic) frozen shoulder, defined by shoulder pain and ≥50% restriction in passive external rotation compared to the contralateral (unaffected) shoulder.\n\nSymptom duration between 3 and 9 months. Average shoulder pain intensity ≥ 4 on a 10-cm Visual Analogue Scale (VAS) over the past week.\n\nNormal or age-appropriate radiographic findings of the glenohumeral joint (ruling out significant arthritis, fractures, calcific tendinitis).\n\nWillingness and ability to attend scheduled treatment\u002Fassessment sessions. Ability to understand study procedures and provide written informed consent.\n\nExclusion Criteria:\n\nSecondary frozen shoulder (e.g., post-traumatic, post-surgical, related to systemic disease like diabetes - clarify if diabetes is excluded or just secondary FS from diabetes).\n\nClinical or imaging evidence of significant rotator cuff tear requiring specific management.\n\nRadiographic evidence of moderate to severe glenohumeral osteoarthritis (e.g., Kellgren-Lawrence grade ≥ 3).\n\nPrevious surgery on the index shoulder. Significant neurological disorders affecting shoulder or upper extremity function (e.g., cervical radiculopathy, stroke).\n\nReceived a corticosteroid injection in the index shoulder within the past 3 months.\n\nKnown contraindications to corticosteroid injections (e.g., uncontrolled diabetes, allergy, local infection).\n\nKnown contraindications to High-Intensity Laser Therapy (e.g., active malignancy in the treatment area, photosensitivity, pacemaker over treatment area).\n\nCurrent participation in another interventional clinical trial for shoulder pain.","ALL","40 Years","70 Years",{"count":91,"type":92},180,"ESTIMATED","INTERVENTIONAL",[95],"NA","This study compares three common treatments for frozen shoulder when added to a standard exercise program: High-Intensity Laser Therapy (HILT), a corticosteroid (steroid) injection into the shoulder joint, and hands-on manual therapy by a physical therapist. A fourth group will receive only the standard exercise program. The goal is to see which combination works best to reduce shoulder pain and improve shoulder function over 6 months. The main outcomes are changes in pain (VAS scale) and shoulder disability (SPADI questionnaire) at 12 weeks.",[98],"Frozen Shoulder","2025-04-01",{"date":101,"type":102},"2025-04-08","ACTUAL",{"date":104,"type":92},"2025-04-25",{"date":106,"type":92},"2027-08-01",{"name":5,"class":6},1]