[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641187":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":37,"locations":43,"responsibleParty":56,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":26,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":84,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Conventional obturation group.","ACTIVE_COMPARATOR","Root canal obturation using resin-based sealer with conventional gutta-percha.",[13],"Procedure: Resin sealer with conventional gutta percha.",{"label":15,"type":16,"description":17,"interventionNames":18},"Bioceramic obturation group.","EXPERIMENTAL","Root canal obturation using bioceramic sealer with bioceramic coated gutta-percha.",[19],"Procedure: Bioceramic sealer with bioceramic gutta-percha.",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Resin sealer with conventional gutta percha.","It is the gold standard obturation technique which will be used as the control group.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Bioceramic sealer with bioceramic gutta-percha.","Bioceramic sealer and bioceramic gutta-percha creating a monoblock for obturation of root canals.",[15],[32,35],{"name":33,"affiliation":5,"role":34},"Ghada Ehab ElWazzan, Lecturer","STUDY_DIRECTOR",{"name":36,"affiliation":5,"role":34},"Alaa ElBaz, Professor",[38],{"name":39,"role":40,"phone":41,"phoneExt":26,"email":42},"Hussein M Taha","CONTACT","+201004421891","hussein.mohamed@dentistry.cu.edu.eg",[44],{"facility":45,"status":26,"city":46,"state":47,"zip":26,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":26},"Out patient clinic Faculty of Dentistry Cairo University","Cairo","Cairo Governorate","Egypt","EG",{"type":51,"coordinates":52},"Point",[53,54],31.24967,30.06263,{"lat":54,"lon":53},{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Hussein Taha","Master Degree Candidate","100641187","comparing-obturation-using-bioceramic-nano-coated-gutta-percha-with-bioceramic-sealer-versus-traditional-gutta-percha-with-resin-sealer-for-reducing-postoperative-pain-and-swelling-after-root-canal-treatment-in-necrotic-single-rooted-teeth-100641187",false,"NCT07600099","Comparing Obturation Using Bioceramic Nano-coated Gutta-percha With Bioceramic Sealer Versus Traditional Gutta-percha With Resin Sealer for Reducing Postoperative Pain and Swelling After Root Canal Treatment in Necrotic Single-rooted Teeth.","Comparative Evaluation of Obturation Using Bioceramic Nano-coated Gutta-percha and Bioceramic-based Sealer Versus Gutta-percha and Resin-based Sealer on Postoperative Pain and Swelling: A Randomized Clinical Trial.","Inclusion Criteria:\n\nPatients aged 20-55 years. Patients with good oral hygiene, free of calculus, and with a probing depth not exceeding 2-3 mm.\n\nNecrotic single-rooted, single-canal permanent teeth with or without periapical lesions. If lesion is present, ranging from 2-5 mm in size.\n\nAbsence of swelling. Medically free patients.\n\nExclusion Criteria:\n\nPatients with poor oral hygiene. Vital teeth. Necrotic teeth without periapical lesions. Primary teeth. Complex root morphology other than Type I. Internal or external root resorption. Vertical root fractures. Cracked teeth. Intraoral or extraoral swelling.",true,"ALL","20 Years","55 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","A randomized clinical trial will compare two root canal filling approaches in necrotic single-rooted teeth. The test group will receive bioceramic mono-block obturation using bioceramic nano-coated gutta-percha with a bioceramic sealer, while the control group will receive traditional gutta-percha with a resin-based sealer. The main aim is to determine whether the bioceramic system can reduce postoperative pain and swelling within 48 hours after treatment compared with the conventional method. Patients aged 20-55 years who have necrotic single-rooted teeth and meet specific clinical and radiographic criteria will be recruited from the outpatient clinics of the Faculty of Dentistry, Cairo University.\n\nPostoperative pain will be measured using a visual analogue scale, and swelling will be assessed using a standardized swelling score at 24 and 48 hours. The study hypothesizes that the bioceramic mono-block technique, due to its improved sealing ability and bioactivity, may lead to less postoperative discomfort and better early clinical outcomes than the gold-standard resin-sealer technique. The findings are expected to provide evidence to guide clinicians on whether adopting bioceramic nano-enhanced obturation can improve patient-centered outcomes after root canal treatment.",[79,80],"Dental Pain","Facial Swelling",[82,83],"bioceramic","monoblock","NOT_YET_RECRUITING","2026-05-18",{"date":87,"type":88},"2026-05-20","ACTUAL",{"date":90,"type":73},"2026-09-01",{"date":92,"type":73},"2027-09-30",{"name":5,"class":6},1]