[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623384":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":31,"responsibleParty":53,"collaborators":26,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":78,"overallStatus":34,"whyStopped":26,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Da Nang Family General Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PIEB Group","EXPERIMENTAL","Maintenance of labor analgesia using Programmed Intermittent Epidural Bolus.",[13],"Procedure: PIEB + PCEA",{"label":15,"type":16,"description":17,"interventionNames":18},"CEI Group","ACTIVE_COMPARATOR","Maintenance of labor analgesia using Continuous Epidural Infusion.",[19],"Procedure: CEI + PCEA",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","PIEB + PCEA","Initial dose: 10 mL (0.1% Ropivacaine + 2 mcg\u002FmL Fentanyl). Maintenance: 8 mL bolus every 60 mins. PCEA: 5 mL bolus, 10-min lockout.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"CEI + PCEA","Initial dose: 10 mL (0.1% Ropivacaine + 2 mcg\u002FmL Fentanyl). Maintenance: Continuous infusion at 8 mL\u002Fhour. PCEA: 5 mL bolus, 10-min lockout.",[15],[32],{"facility":33,"status":34,"city":35,"state":26,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Family General Hospital","RECRUITING","Da Nang","50000","Vietnam","VN",{"type":40,"coordinates":41},"Point",[42,43],108.22083,16.06778,{"lat":43,"lon":42},[46,51],{"name":47,"role":48,"phone":49,"phoneExt":26,"email":50},"Thi Lan Phuong Nguyen, MD, MSc","CONTACT","+84375410293","lanphuongydh@gmail.com",{"name":47,"role":52,"phone":26,"phoneExt":26,"email":26},"PRINCIPAL_INVESTIGATOR",{"type":54,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100623384","comparing-pieb-and-cei-for-labor-pain-relief-100623384",false,"NCT07395934","Comparing PIEB and CEI for Labor Pain Relief","Comparison of Continuous Epidural Infusion vs. Programmed Intermittent Epidural Bolus Combined With Patient-Controlled Epidural Analgesia for Labor Pain Relief: A Randomized Controlled Trial","COPILOT","Inclusion Criteria:\n\n* Parturients indicated for labor analgesia for vaginal delivery via epidural anesthesia.\n* Age from 18 to 40 years.\n* Physical status: ASA II.\n* Singleton pregnancy, full-term, vertex presentation in labor.\n* Indication for vaginal delivery.\n* No contraindications to epidural anesthesia.\n* Agreement to participate in the research and signed written informed consent.\n\nExclusion Criteria:\n\n* Contraindications to epidural analgesia.\n* History of allergy to local anesthetics (Ropivacaine) or opioids (Fentanyl).\n* High-risk pregnancies: Preeclampsia, placenta previa, placental abruption.\n* Fetal distress or fetal abnormalities.\n* Chronic use of analgesic drugs or neurological\u002Fpsychiatric disorders.\n* Parturients who refuse to participate or request to withdraw from the research.","FEMALE","18 Years","40 Years",{"count":67,"type":68},60,"ESTIMATED","INTERVENTIONAL",[71],"NA","The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural Infusion (CEI), both combined with Patient-Controlled Epidural Analgesia (PCEA). The study aims to evaluate which technique provides superior analgesia while minimizing anesthetic consumption and preserving maternal motor function. A total of 60 parturients at Family Hospital, Da Nang, will be randomly assigned to either the PIEB or CEI group. Outcomes including pain intensity (VAS scores), total drug consumption, maternal satisfaction, and neonatal Apgar scores will be assessed.",[74,75,76,77],"Labor Pain","Analgesia, Epidural","Analgesia, Obstetrical","Labor, Obstetric",[79,80,81,82],"Programmed Intermittent Epidural Bolus (PIEB)","Continuous Epidural Infusion (CEI)","Patient-Controlled Epidural Analgesia (PCEA)","Visual Analog Scale (VAS)","2026-01-31",{"date":85,"type":86},"2026-02-09","ACTUAL",{"date":88,"type":86},"2025-07-30",{"date":90,"type":68},"2026-08-30",{"name":5,"class":6},1]