[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622416":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":24,"responsibleParty":35,"collaborators":24,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":24,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":24,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":61,"whyStopped":24,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":24},{"fullName":5,"class":6},"Royal College of Surgeons in Ireland - Medical University of Bahrain","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: Fragrance loaded with a concentration of SpECs grains.","EXPERIMENTAL","Fragrance delivery system: SpECs loaded with fragrance (50mg\u002Fml perfume)",[13],"Other: Fragrance",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B: Fragrance loaded without SpECs grains","ACTIVE_COMPARATOR","fragrance without SpECs",[13],[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Fragrance","this intervention involves the controlled use of specific fragrance with and withouth SpECs grains",[9,15],null,[26],{"name":27,"affiliation":28,"role":29},"Mariam Murad","Royal College of Surgeons, Ireland","PRINCIPAL_INVESTIGATOR",[31],{"name":27,"role":32,"phone":33,"phoneExt":24,"email":34},"CONTACT","16660087","mmurad@rcsi.com",{"type":36,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100622416","comparing-the-olfactory-perception-of-a-fragrance-loaded-specs-over-time-100622416",false,"NCT07383337","Comparing the Olfactory Perception of a Fragrance-Loaded SpECs Over Time","A Randomized, Double-blind Crossover Pilot Trial to Compare the Olfactory Perception of a Fragrance-Loaded SpECs Over Time","Inclusion Criteria:\n\n* Females aged between 18 and 45 years.\n* No history of olfactory impairment, allergies to pollen or fragrances, or skin conditions.\n\nExclusion Criteria:\n\n* Current use of medications that affect olfactory function (e.g., antihistamines).\n* Pregnancy or breastfeeding.\n* Any active upper respiratory tract infection within 2 weeks of the clinical trial\n* Any known skin allergy.",true,"FEMALE","18 Years","45 Years",{"count":49,"type":50},10,"ESTIMATED","INTERVENTIONAL",[53],"NA","The human olfactory system plays a crucial role in sensory perception, influencing emotional states, memory, and interpersonal interactions(1). Fragrance durability and intensity are critical factors in the evaluation of perfumes and other scented products. The ability of fragrance formulations to maintain consistent scent intensity over time is a major contributor to a product's overall efficacy and consumer satisfaction,\n\nPrimary Aim To compare the perceived strength of a topical fragrance delivered via SpECs across a period of 8 hours using subjective ratings by participants and an independent examiner.\n\nObjectives\n\n1. To investigate whether the encapsulated fragrance intensity, as perceived by participants, decreases less over time compared with fragrance alone, after application to the skin.\n2. To investigate whether the encapsulated fragrance intensity, as perceived by an independent examiner, decreases less over time compared with fragrance alone, after application to the skin.",[56],"Perception, Self",[58,59,60],"fragrance","SpECs","Olfactory","NOT_YET_RECRUITING","2026-02-03",{"date":64,"type":65},"2026-02-05","ACTUAL",{"date":67,"type":50},"2026-02-15",{"date":69,"type":50},"2026-03-01",{"name":5,"class":6}]