[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581532":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":39,"locations":45,"responsibleParty":58,"collaborators":31,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":31,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":31,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":47,"whyStopped":31,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Medipol University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"No Block (Control Group)","ACTIVE_COMPARATOR","Patients receive standard perioperative analgesia without any additional regional block.",[13],"Procedure: Standard Analgesia (No Block)",{"label":15,"type":16,"description":17,"interventionNames":18},"TLIP Block","EXPERIMENTAL","Patients receive the Thoracolumbar Interfascial Plane (TLIP) block in addition to standard perioperative analgesia.",[19],"Procedure: Thoracolumbar Interfascial Plane (TLIP) Block",{"label":21,"type":16,"description":22,"interventionNames":23},"Quadro Iliac Plane Block","Patients receive the Quadro Iliac Plane Block in addition to standard perioperative analgesia.",[24],"Procedure: Quadro Iliac Plane Block",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"PROCEDURE","Standard Analgesia (No Block)","Participants receive standard perioperative analgesia (including intravenous paracetamol\u002Ftramadol), but no additional regional block is applied.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Thoracolumbar Interfascial Plane (TLIP) Block","In addition to standard perioperative analgesia, a TLIP block is performed under sterile conditions and ultrasound guidance, after the surgical procedure is completed but before the patient is awakened. A total of 20 mL of 0.25% bupivacaine is injected into the thoracolumbar fascial plane, and spread is confirmed via ultrasound.",[15],{"type":27,"name":21,"description":37,"armGroupLabels":38,"otherNames":31},"In addition to standard perioperative analgesia, a Quadro Iliac Plane Block is performed under sterile conditions and ultrasound guidance, after the surgical procedure is completed but before the patient is awakened. A total of 20 mL of 0.25% bupivacaine is injected into the quadro iliac plane at the level of the iliac crest, and spread is confirmed via ultrasound.",[21],[40],{"name":41,"role":42,"phone":43,"phoneExt":31,"email":44},"Burak Ömür","CONTACT","+905056215056","burakomur@outlook.com",[46],{"facility":5,"status":47,"city":48,"state":31,"zip":31,"country":49,"countryCode":31,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Istanbul","Turkey (Türkiye)",{"type":51,"coordinates":52},"Point",[53,54],28.94966,41.01384,{"lat":54,"lon":53},[57],{"name":41,"role":42,"phone":43,"phoneExt":31,"email":44},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Burak Omur","Assistant Professor","100581532","comparing-thoracolumbar-interfascial-and-quadro-iliac-plane-blocks-on-postoperative-opioid-use-following-lumbar-microsurgery-100581532",false,"NCT06851533","Comparing Thoracolumbar Interfascial and Quadro Iliac Plane Blocks on Postoperative Opioid Use Following Lumbar Microsurgery","Comparison of the Effects of Thoracolumbar Interfascial Plane Block and Quadro Iliac Plane Block on Postoperative Opioid Consumption After Lumbar Microsurgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18 to 80 years\n* American Society of Anesthesiologists (ASA) physical status I to III\n* scheduled for lumbar microdiscectomy surgery\n\nExclusion Criteria:\n\n* Known allergy to local anesthetics\n* Any other significant drug allergies related to the study interventions\n* Pregnancy\n* Pre-existing psychiatric or neurological disorders\n* Inability to provide informed consent","ALL","18 Years","80 Years",{"count":73,"type":74},90,"ESTIMATED","INTERVENTIONAL",[77],"NA","Lumbar microdiscectomy is a commonly used surgical procedure for treating herniated discs. Effective postoperative analgesia is crucial for early mobilization and functional recovery. Uncontrolled postoperative pain can delay recovery, increase the risk of opioid dependence, and lead to respiratory complications.\n\nAlthough opioid analgesics effectively reduce pain, they can cause side effects such as nausea, vomiting, respiratory depression, and dependency. Therefore, non-opioid analgesic methods are preferred for patient safety and comfort. Recently, regional anesthesia techniques such as the Thoracolumbar Interfascial Plane (TLIP) block and the Quadro Iliac Plane Block have been introduced for postoperative pain management in lumbar surgeries. However, there are not enough studies comparing the superiority of these two methods.\n\nStudy Objective: The primary aim of this study is to evaluate the effects of ultrasound-guided TLIP and Quadro Iliac Plane Blocks on postoperative opioid consumption after lumbar microsurgery. The secondary aim is to compare opioid-related side effects (such as nausea, vomiting, respiratory depression, etc.) and postoperative NRS pain scores between the groups.",[80,81],"Lumbar Microdiscectomy","Nerve Block",[83,84],"Postoperative pain","Ultrasound-guided nerve block","2025-12-01",{"date":87,"type":88},"2025-12-08","ACTUAL",{"date":90,"type":88},"2025-03-10",{"date":92,"type":74},"2026-04-10",{"name":5,"class":6},1]