[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611089":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":37,"centralContacts":42,"locations":30,"responsibleParty":52,"collaborators":30,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":30,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":30,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":77,"whyStopped":30,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":83,"leadSponsor":85,"locationsCount":30},{"fullName":5,"class":6},"Alexandria University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"lay open","ACTIVE_COMPARATOR","fistula lay open of the tract",[13],"Procedure: fistula lay open",{"label":15,"type":10,"description":16,"interventionNames":17},"LIFT plus LASER","ligation of inters-sphincteric tract plus laser for the outer tract",[18],"Procedure: LIFT plus LASER",{"label":20,"type":10,"description":21,"interventionNames":22},"open LIFT plus LASER","cutting internal sphincter and ligation of tract plus LASER to outer part",[23],"Procedure: open LIFT plus LASER",[25,31,34],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","fistula lay open","lay open of fistula tract",[9],null,{"type":26,"name":15,"description":32,"armGroupLabels":33,"otherNames":30},"ligation of inter-sphincteric tract plus LASER of tract",[15],{"type":26,"name":20,"description":35,"armGroupLabels":36,"otherNames":30},"cutting of internal anal sphincter plus ligation of inter-sphincteric tract plus LASER",[20],[38],{"name":39,"affiliation":40,"role":41},"Walid GALAL Elshazly, Prof","University of Alexandria","PRINCIPAL_INVESTIGATOR",[43,48],{"name":44,"role":45,"phone":46,"phoneExt":30,"email":47},"Walid galal Elshazly, PROF","CONTACT","+201221100756","wshazly@gmail.com",{"name":49,"role":45,"phone":50,"phoneExt":30,"email":51},"omar walid ELShazly, GP","+201110711943","omarshazly2001@gmail.com",{"type":53,"investigatorFullName":30,"investigatorTitle":30,"investigatorAffiliation":30,"oldNameTitle":30,"oldOrganization":30},"SPONSOR","100611089","comparing-three-surgical-techniques-for-the-treatment-of-transsphincteric-perianal-fistula-1-traditional-fistulotomy-lay-open-2-ligation-of-the-intersphincteric-tract-lift-with-adjunctive-endo-fistula-laser-ablation-and-3-open-lift-procedure-followed-by-laser-100611089",false,"NCT07236047","Comparing Three Surgical Techniques for the Treatment of Transsphincteric Perianal Fistula: (1) Traditional Fistulotomy (Lay Open), (2) Ligation of the Intersphincteric Tract (LIFT) With Adjunctive Endo Fistula Laser Ablation, and (3) Open LIFT Procedure Followed by LASER","Randomized Controlled Trial Comparing Fistulotomy vs LIFT Plus Laser Ablation vs Open LIFT Plus Laser in the Treatment of Trans-sphincteric Perianal Fistula","Inclusion Criteria:\n\n* Adults aged 18-65\n* Confirmed diagnosis of transsphincteric cryptoglandular perianal fistula\n* Primary (first-time) surgery\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Crohn's disease or other inflammatory bowel disease\n* Suprasphincteric, extrasphincteric, or horseshoe fistulas\n* Previous fistula surgery\n* Active perianal abscess\n* Current immunosuppression\n* Pregnant or breastfeeding women","ALL","18 Years","65 Years",{"count":65,"type":66},90,"ESTIMATED","INTERVENTIONAL",[69],"NA","\\>This randomized clinical trial compares three different surgical techniques for the treatment of transsphincteric perianal fistula: (1) traditional fistulotomy (lay open), (2) ligation of the intersphincteric tract (LIFT) with adjunctive endofistula laser ablation, and (3) open LIFT procedure followed by direct laser ablation of the tract under vision. The aim is to determine which approach offers the highest healing rate, lowest recurrence, and best postoperative outcomes with minimal impact on continence.",[72],"Perianal Fistula",[74,75,76],"LIFT","perianal fistula","LASER","NOT_YET_RECRUITING","2025-11-20",{"date":80,"type":81},"2025-11-21","ACTUAL",{"date":78,"type":66},{"date":84,"type":66},"2027-09-01",{"name":5,"class":6}]