[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641879":3},{"organization":4,"outcomesModule":7,"designInfo":19,"detailedDescription":28,"studyPopulation":18,"armGroups":29,"interventions":41,"overallOfficials":18,"centralContacts":49,"locations":58,"responsibleParty":66,"collaborators":18,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":18,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":98,"whyStopped":18,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"University of Faisalabad","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":18},[9],{"measure":10,"description":11,"timeFrame":12},"Visual analogue scale","Comparison on effect of pain. The Visual Analog Scale is a self-reported measure of pain intensity. Participants rate their pain on a 10-cm scale ranging from 0 to 10, where 0 indicates \"no pain\" and 10 indicates \"worst imaginable pain.\"","Baseline and 4 week post intervention",[14],{"measure":15,"description":16,"timeFrame":17},"Lower Extremity Functional Scale","Comparison on effect of functional outcomes. The Lower Extremity Functional Scale (LEFS) is a self-reported questionnaire used to assess functional status and difficulty performing everyday activities in individuals with lower extremity musculoskeletal conditions. The scale consists of 20 items, each scored from 0 to 4, yielding a total score ranging from 0 to 80.","Baseline and 4 week of post intervention",null,{"allocation":20,"interventionModel":21,"interventionModelDescription":18,"primaryPurpose":22,"observationalModel":18,"timePerspective":18,"maskingInfo":23},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":24,"maskingDescription":18,"whoMasked":25},"DOUBLE",[26,27],"PARTICIPANT","OUTCOMES_ASSESSOR","This is Multiple-center, randomized controlled trail. Participants age 20-50 years with diagnosed piriformis syndrome will be referred from neuro physician and orthopedic department of Madina Teaching hospital (MTH) to Physiotherapy ward, Jafar Physiotherapy Clinic and Madina Specilaists Clinic. After informed consent Participants will be randomly assign to one of two parallel groups using a random number generator. Group A (Experimental): Receive MFR 3 sessions per week for total duration 4 weeks. Group B (Active Comparator) receive the PIR 3 sessions per week for total duration 4 weeks. Outcome measures (pain via VAS, functional status via LEFS) are taken at baseline and end of treatment. Data will be analyzed using Spss version 20.",[30,36],{"label":31,"type":32,"description":33,"interventionNames":34},"Myofascial release","EXPERIMENTAL","Myofascial release was then performed with the patient positioned in prone lying. The piriformis muscle was identified. Sustained pressure was applied directly to the trigger point\u002Fpiriformis muscle for 10-100 seconds while the patient actively moved the affected limb repeatedly from internal to external rotation. Kneading strokes parallel to the muscle fibers were then performed for 5 minutes to promote elongation. This sequence was repeated three times.",[35],"Other: Myofascial Release",{"label":37,"type":32,"description":38,"interventionNames":39},"Post Isometric Relaxation","The patient is in supine and the hip in neutral rotation. The affected hip was passively moved into horizontal adduction until a mild stretch was felt, while the lumbar spine was stabilized. The patient performed a gentle isometric contraction into hip abduction for 7-10 seconds, followed by 2-3 seconds of relaxation. The leg was then moved into further adduction to a new barrier.\n\nThis contraction-relaxation-stretch cycle was performed for 3 sets of 5 repetitions.",[40],"Other: Post Isometric Relaxation",[42,46],{"type":6,"name":43,"description":44,"armGroupLabels":45,"otherNames":18},"Myofascial Release","Myofascial release is performed with the patient positioned in prone lying. The piriformis muscle was identified. Sustained pressure was applied directly to the trigger point\u002Fpiriformis muscle for 10-100 seconds while the patient actively moved the affected limb repeatedly from internal to external rotation. Kneading strokes parallel to the muscle fibers were then performed for 5 minutes to promote elongation. This sequence was repeated three times.",[31],{"type":6,"name":37,"description":47,"armGroupLabels":48,"otherNames":18},"Post-isometric relaxation (PIR) is performed with the patient in supine and the hip in neutral rotation. The affected hip was passively moved into horizontal adduction until a mild stretch was felt, while the lumbar spine was stabilized. The patient performed a gentle isometric contraction into hip abduction for 7-10 seconds, followed by 2-3 seconds of relaxation. The leg was then moved into further adduction to a new barrier.",[37],[50,55],{"name":51,"role":52,"phone":53,"phoneExt":18,"email":54},"Dr. Muhammad Muneeb Jafar, PhD Physiotherapy","CONTACT","+923127000616","Muneebjafar.DPT@tuf.edu.pk",{"name":56,"role":52,"phone":57,"phoneExt":18,"email":18},"Dr. Muhammad Ateeb, PhD Public Health","+923357333383",[59],{"facility":60,"status":18,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":18,"geoPoint":18,"contacts":18},"The University of Faisalabad","Faisalābad","Punjab Province","38000","Pakistan","PK",{"type":67,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Muhammad Muneeb Jafar","Assistant Professor, Department of Rehabilitation Sciences","100641879","comparing-two-soft-tissues-technique-on-piriformis-syndrome-patients-100641879",false,"NCT07661485","Comparing Two Soft Tissues Technique on Piriformis Syndrome Patients","Effect of Myofascial Release as Compared to Post Isometric Relaxation in Improving Pain and Lower Extremity Function in Piriformis Syndrome","MPR-PIR","Inclusion Criteria:\n\n* Positive Lasegue sign\n* Positive FAIR test\n* Grade 1-3 tenderness on palpation of piriformis between sacrum and greater trochanter of femur\n* 4 or more pain intensity on the VAS scale\n\nExclusion Criteria:\n\n* Lower extremity injuries including ligament, tendon injuries, muscle strains as well as nerve injuries\n\n  * Systemic diseases including tuberculosis, multiple sclerosis, Parkinson's disease as well as chronic inflammatory conditions\n  * Congenital deformities including hip dysplasia, limb length discrepancy, scoliosis and congenital pelvic asymmetry\n  * Cognitive issues including dementia, severe depression and severe psychotic disorders\n  * Lumbar Radiculopathy\n  * SIJ Dysfunction\n  * Lower Extremity Fractures\n  * Pregnancy\n  * Malignancy","ALL","20 Years","50 Years",{"count":82,"type":83},26,"ESTIMATED","INTERVENTIONAL",[86],"NA","Piriformis Syndrome is a neuromuscular condition with symptoms of pain, numbness and tingling tracing the route of the sciatic nerve, due to the nerve impingement by the piriformis muscle. Two common manual therapy techniques used to treat musculoskeletal conditions are myofascial release and post-isometric relaxation. The intent of the research is to evaluate the effects of myofascial release (MFR) as compared to post-isometric relaxation (PIR) in improving pain and lower extremity function in piriformis syndrome (LEFS). The study population involved 32 individuals aged between 20 to 50 years who will be randomly assigned to two groups; a group that received MFR and a group that received PIR. Both groups received the baseline treatment for four weeks. The Visual Analog Scale (VAS) will be employed to gauge the amount of pain, while the LEFS was used to measure functional mobility",[89,90,91],"Piriformis Syndrome","Musculoskeletal Abnormalities","Sciatica",[93,94,95,96,97],"myofasical release","Post isometric relaxation","physiotherapy","Radiculopathy","Piriformis syndrome","NOT_YET_RECRUITING","2026-06-25",{"date":101,"type":102},"2026-06-30","ACTUAL",{"date":101,"type":83},{"date":105,"type":83},"2026-09-30",{"name":5,"class":6},1]