[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623475":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":69,"collaborators":26,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":26,"enrollmentInfo":81,"targetDuration":26,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Transgluteal sciatic nerve block","EXPERIMENTAL","Patients will receive an ultrasound-guided transgluteal sciatic nerve block with 10-20 mL of 0.2% ropivacaine injected around the affected sciatic nerve at the level of the greater trochanter.",[13],"Procedure: nerve block with ropivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard of care","ACTIVE_COMPARATOR","Standard ED analgesic management per departmental protocols (oral\u002FIV NSAIDs, acetaminophen, opioids, muscle relaxants).",[19],"Other: Standard medical treatment",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","nerve block with ropivacaine","Ultrasound-guided transgluteal sciatic nerve block with 10-20 mL of 0.2% ropivacaine injected around the affected sciatic nerve at the level of the greater trochanter",[9],null,{"type":6,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Standard medical treatment",[15],[31],{"name":32,"affiliation":5,"role":33},"Jeanne Noble, MD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},"Tianyu Tang, MD","CONTACT","628-247-7578","tianyu.tang@ucsf.edu",{"name":41,"role":37,"phone":26,"phoneExt":26,"email":42},"Felipe Ocampo, MD","felipe.ocampo@ucsf.edu",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","San Francisco","California","94107","United States","US",{"type":52,"coordinates":53},"Point",[54,55],-122.41942,37.77493,{"lat":55,"lon":54},[58,59,62,64,66,67,68],{"name":36,"role":37,"phone":38,"phoneExt":26,"email":39},{"name":60,"role":61,"phone":26,"phoneExt":26,"email":26},"Kavita Gandhi, MD","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":26,"phoneExt":26,"email":26},"Nancy Anaya, MD",{"name":65,"role":61,"phone":26,"phoneExt":26,"email":26},"Jeffrey Merz-Herrala, MD",{"name":36,"role":61,"phone":26,"phoneExt":26,"email":26},{"name":41,"role":61,"phone":26,"phoneExt":26,"email":26},{"name":32,"role":33,"phone":26,"phoneExt":26,"email":26},{"type":70,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100623475","comparing-ultrasound-guided-transgluteal-nerve-block-to-standard-care-100623475",false,"NCT07397117","Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care","Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care for Emergency Department Patients With Low Back Pain and Sciatic Radiculopathy: A Randomized Controlled Trial","TGSNB vs SoC","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Presentation to ED with:\n* Acute or acute-on-chronic pain consistent with sciatica, defined as unilateral lumbosacral radicular pain radiating from the lower back or gluteal region to the posterior leg, may extend distal to the knee.\n* Pain score ≥ 5\u002F10 on Numeric Rating Scale (NRS)\n\nExclusion Criteria:\n\n* Known allergy to study medications (e.g., local anesthetics)\n* Coagulopathy or current anticoagulation therapy\n* Suspected or confirmed spinal infection, or tumor\n* Neurological deficits (bowel or bladder dysfunction, leg weakness)\n* Inability to provide informed consent","ALL","18 Years",{"count":82,"type":83},100,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department.\n\nThe main question it aims to answer is: Is a transgluteal sciatic nerve block better than standard of care in improving pain in ER patients with sciatic back pain?\n\nIf there is a comparison group: Researchers will compare patients who receive transgluteal sciatic nerve blocks to patients who receive standard of care to see if pain scores improve in ER patients with sciatic back pain.\n\nParticipants will be randomized into the transgluteal sciatic nerve block group or the control group (standard of care). Participants will be asked to answer questions about their pain and will be asked to walk a timed short distance.",[89],"Sciatica Acute",[91,92,93,94],"sciatica","sciatic back pain","lumbar radiculopathy","sciatic radiculopathy","2026-05-29",{"date":97,"type":98},"2026-06-02","ACTUAL",{"date":100,"type":98},"2026-05-26",{"date":102,"type":83},"2027-01-31",{"name":5,"class":6},1]