[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522083":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":56,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":25,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Instituto do Cancer do Estado de São Paulo","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hydroxyethylamide Group","ACTIVE_COMPARATOR","15 will be from the hydroxyethylamide Group, where the submucosal endoscopic dissection will be performed with submucosal injection of hydroxyethylamide.",[13],"Procedure: Submucous Endoscopic Dissection with hydroxyethylamide",{"label":15,"type":10,"description":16,"interventionNames":17},"Hyaluronic acid group (TS-905 Blue Eye)","15 will be from the Hyaluronic acid group (TS-905 Blue Eye), where the submucosal endoscopic dissection with submucosal injection of hyaluronic acid (TS-905 Blue Eye) will be performed.",[18],"Procedure: Submucous Endoscopic Dissection with Hyaluronic acid (TS-905 Blue Eye)",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Submucous Endoscopic Dissection with hydroxyethylamide","The resection will be performed in three stages using hydroxyethylamide : delimitation, incision and dissection. Initially we will inject the hydroxyethylamide and examine the delimitation of the lesion. With Knife itself, using soft or Forced coagulation current, we will circumvent the limits of the lesion with punctual coagulations 5 mm away from it.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Submucous Endoscopic Dissection with Hyaluronic acid (TS-905 Blue Eye)","The resection will be performed in three stages using Hyaluronic acid (TS-905 Blue Eye) : delimitation, incision and dissection. Initially we will inject the Blue-Eyed and examine the delimitation of the lesion. With Knife itself, using soft or Forced coagulation current, we will circumvent the limits of the lesion with punctual coagulations 5 mm away from it.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Fauze Maluf-Filho, PhD","CONTACT","+5511991919014","fauze.maluf@terra.com.br",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Pierre Pirchner","+5521986979456","pierrepmm@hotmail.com",[41],{"facility":42,"status":43,"city":44,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Instituto do Câncer do Estado de São Paulo","RECRUITING","São Paulo","01246-000","Brazil","BR",{"type":49,"coordinates":50},"Point",[51,52],-46.63611,-23.5475,{"lat":52,"lon":51},[55],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Fauze Maluf Filho","Principal Investigator","100522083","comparison-of-04-hyaluronic-acid-solution-versus-hydroxyethylamide-solution-in-submucosal-endoscopic-resections-100522083",false,"NCT06077981","Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections","Comparison of 0.4% Hyaluronic Acid Solution Versus Hydroxyethylamide Solution in Submucosal Endoscopic Resections of Superficial Malignant Esophageal Neoplasms: a Randomized Clinical Trial.","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Superficial esophageal adenocarcinoma or squamous cell carcinoma with indication of ESD after discussion in a multidisciplinary oncological board\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Residual or recurrent esophageal lesions\n* Ulcerated esophageal lesions\n* Patients with severe cardiovascular, kidney or liver disease\n* History of hypersensitivity to hyaluronic acid\n* Pregnant or lactating women","ALL","18 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","This is a randomized, single-center clinical trial that will compare the efficacy of two substances used in the submucosal cushion formation stage of endoscopic submucosal resections of early esophageal malignant neoplasms. Such substances are hyaluronic acid in the form of TS-905 Blue Eyeₒ and hydroxyethylamide (Voluven®).",[77,78,79],"Esophageal Neoplasms","Endoscopic Mucosal Resection","Hyaluronic Acid",[77,78,79],"2025-04-29",{"date":83,"type":84},"2025-05-01","ACTUAL",{"date":86,"type":84},"2023-06-19",{"date":88,"type":71},"2026-04-13",{"name":5,"class":6},1]