[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568561":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":24,"responsibleParty":40,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":10,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":10,"enrollmentInfo":53,"targetDuration":56,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Hacettepe University","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"COPD group",null,"Consisted of 18 individuals over 40 years of age with chronic obstructive pulmonary disease.",{"label":13,"type":10,"description":14,"interventionNames":10},"PRISm group","Consisted of 18 individuals over 40 years of age with preserved ratio impaired spirometry.",{"label":16,"type":10,"description":17,"interventionNames":10},"Healthy group","Consisted of 18 healthy individuals over 40 years of age.",[19],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Ece Kumlu, M.Sc","CONTACT","+90-312-305 2525 ext 178","eekumlu@gmail.com",[25],{"facility":5,"status":26,"city":27,"state":10,"zip":28,"country":29,"countryCode":10,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"RECRUITING","Ankara","06560","Turkey (Türkiye)",{"type":31,"coordinates":32},"Point",[33,34],32.85427,39.91987,{"lat":34,"lon":33},[37],{"name":38,"role":21,"phone":39,"phoneExt":10,"email":23},"Ece Kumlu","05535637892",{"type":41,"investigatorFullName":38,"investigatorTitle":42,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100568561","comparison-of-clinical-status-of-individuals-with-copd-and-preserved-ratio-impaired-spirometry-100568561",false,"NCT06682832","Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry","Comparison of Exercise Capacity, Muscle Strength and Oxygenation, Arterial Stiffness, Physical Activity and Quality of Life in Individuals With Chronic Obstructive Pulmonary Disease and Impaired Spirometry With Preserved Ratio","Inclusion Criteria:\n\nPRISm group inclusion criteria;\n\n* Being \\>40 years old,\n* Being diagnosed with PRISm,\n* Volunteering to participate in the study,\n* Not having any orthopaedic or neurological problems that may prevent participation in the measurements,\n* Co-operation with measurements\n\nInclusion criteria for the COPD group;\n\n* Being \\>40 years old,\n* Being diagnosed with COPD,\n* To be clinically stable,\n* Volunteering to participate in the study.\n\nInclusion criteria for healthy individuals;\n\n* Being \\>40 years old,\n* Volunteering to participate in the study,\n* No known chronic health problems,\n* To be able to co-operate with the measurements.\n\nExclusion Criteria:\n\nPRISm group exclusion criteria;\n\n* Being diagnosed with COPD,\n* Severe orthopaedic, neurological and cardiac diseases\n* Not volunteering to participate in the study\n\nExclusion criteria for COPD group;\n\n* Severe orthopaedic, neurological and cardiac diseases,\n* Being in COPD exacerbation period,\n* Not volunteering to participate in the study.\n\nHealthy individuals exclusion criteria;\n\n* Having a known chronic disease,\n* Not volunteering to participate in the study",true,"ALL","40 Years",{"count":54,"type":55},54,"ESTIMATED","1 Day","OBSERVATIONAL","Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management. Further studies are needed on appropriate approaches for individuals with PRISm to improve respiratory symptoms and prognosis. As research continues to evolve, PRISm needs to be recognized as a critical component of pulmonary assessments and at-risk individuals need to be provided with appropriate treatment and follow-up to prevent progression to COPD. There are no studies in the literature comparing PRISm, respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in COPD and healthy individuals. The aim of this study was to compare respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in PRISm, COPD and healthy subjects.",[60,61],"Chronic Obstructive Pulmonary Disease (COPD)","Preserved Ratio Impaired Spirometry (PRISM)",[63,64,65,66,67,68],"COPD","PRISm","exercise capacity","muscle strength","arterial stiffness","physical activity","2026-03-27",{"date":71,"type":72},"2026-03-31","ACTUAL",{"date":74,"type":72},"2025-09-18",{"date":76,"type":55},"2026-09",{"name":5,"class":6},1]