[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590387":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":33,"locations":43,"responsibleParty":63,"collaborators":32,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":32,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":32,"overallStatus":46,"whyStopped":32,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Vilnius University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CPAP","ACTIVE_COMPARATOR","Patients under CPAP respiratory support.",[13],"Other: NIPPV",{"label":15,"type":16,"description":17,"interventionNames":18},"NIPPV","EXPERIMENTAL","Patients under Noninvasive positive pressure ventilation (NIPPV).",[19],"Other: CPAP",[21,26],{"type":6,"name":15,"description":22,"armGroupLabels":23,"otherNames":24},"NIPPV\n\n* PEEP 6-8 cmH2O\n* PIP: 14-16 cmH2O\n* Tinsp: 0.3-0.5sec\n\n  * \\\u003C28 weeks GA: 0.3 - 0.4 sec\n  * \\>28weeks GA: 0.4 - 0.5 sec\n* Rate: 20-35 breaths per minute.",[9],[25],"Noninvasive positive pressure ventilation",{"type":6,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"CPAP pressure of 6-8 mmH2O",[15],[30,31],"Nasal Continuous Airway Pressure","nCPAP",null,[34,39],{"name":35,"role":36,"phone":37,"phoneExt":32,"email":38},"Arunas Liubsys, Associate Professor","CONTACT","+370 6 872 2520","arunas.liubsys@santa.lt",{"name":40,"role":36,"phone":41,"phoneExt":32,"email":42},"Ernestas Virsilas","+37060787438","ernestas.virsilas@santa.lt",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Vilnius University Santaros Klinikos","RECRUITING","Vilnius","Vilnius County","08661","Lithuania","LT",{"type":53,"coordinates":54},"Point",[55,56],25.2798,54.68916,{"lat":56,"lon":55},[59,62],{"name":60,"role":36,"phone":61,"phoneExt":32,"email":38},"Arunas Liubsys","+37068722520",{"name":40,"role":36,"phone":41,"phoneExt":32,"email":42},{"type":64,"investigatorFullName":60,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"PRINCIPAL_INVESTIGATOR","Associate professor","100590387","comparison-of-continuous-positive-airway-pressure-cpap-and-non-invasive-positive-pressure-ventilation-nippv-in-preterm-newborns-with-respiratory-distress-syndrome-100590387",false,"NCT06966752","Comparison of Continuous Positive Airway Pressure (CPAP) and Non-Invasive Positive Pressure Ventilation (NIPPV) in Preterm Newborns With Respiratory Distress Syndrome.","Randomized Control Trial: Nasal CPAP vs. NIPPV in Preterm Infants With Respiratory Distress Syndrome","NC3","Inclusion Criteria:\n\n1. gestational age (GA) between 22+0 and 34+6 weeks (estimated on the postmenstrual date and early gestation ultrasonographic findings).\n2. Need of respiratory support (deemed by a clinician).\n\nExclusion Criteria:\n\n1. Major congenital anomalies\n2. Cardiovascular instability\n3. Consent refused or not provided","ALL","0 Minutes","44 Weeks",{"count":78,"type":79},150,"ESTIMATED","INTERVENTIONAL",[82],"NA","Primary objective: to evaluate safety and efficacy of two different non-invasive respiratory support modalities in preterm neonatal patients with respiratory distress syndrome.\n\nSecondary objective is to compare different respiratory support mode performance in different gestational age groups.\n\nPrimary endpoint is treatment failure.\n\nWith this study, the following hypotheses will be tested:\n\nHypothesis 1: NIPPV has a lower failure rate compared to CPAP mode. Hypothesis 2: NIPPV complication rate is non-superior compared to CPAP.",[85],"Respiratory Distress Syndrome (RDS)","2025-05-07",{"date":88,"type":89},"2025-05-13","ACTUAL",{"date":91,"type":89},"2025-03-25",{"date":93,"type":79},"2027-05-01",{"name":5,"class":6},1]