[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644019":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":24,"centralContacts":29,"locations":34,"responsibleParty":45,"collaborators":10,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":9,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":67,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Antalya Health Sciences University","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"DAIR",null,[12],"Other: DAIR",{"label":14,"type":10,"description":10,"interventionNames":15},"Implant removal\u002Freplacement",[16],"Other: Implant removal\u002Freplacement",[18,21],{"type":6,"name":9,"description":19,"armGroupLabels":20,"otherNames":10},"DAIR: Debridement, antibiotic retention and implant removal",[9],{"type":6,"name":14,"description":22,"armGroupLabels":23,"otherNames":10},"implant removal\u002Freplacement",[14],[25],{"name":26,"affiliation":27,"role":28},"Melih Unal","University of Health Sciences, Antalya Training and Research Hospital","PRINCIPAL_INVESTIGATOR",[30],{"name":26,"role":31,"phone":32,"phoneExt":10,"email":33},"CONTACT","+905055278002","meliih.unal@gmail.com",[35],{"facility":27,"status":36,"city":37,"state":10,"zip":10,"country":38,"countryCode":10,"cosmosGeoPoint":39,"geoPoint":44,"contacts":10},"RECRUITING","Antalya","Turkey (Türkiye)",{"type":40,"coordinates":41},"Point",[42,43],30.69556,36.90812,{"lat":43,"lon":42},{"type":46,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100644019","comparison-of-debridement-antibiotic-implant-retention-and-implant-exchange-in-early-stage-fracture-related-infections-100644019",false,"NCT07669714","Comparison of Debridement, Antibiotic, Implant Retention and Implant Exchange in Early-stage Fracture-related Infections","COMPARISON OF DEBRIDEMENT, ANTIBIOTIC, IMPLANT RETENTION (DAIR) AND IMPLANT EXCHANGE IN EARLY-STAGE FRACTURE-RELATED INFECTIONS: A RETROSPECTİVE COHORT STUDY","Inclusion Criteria:\n\n* internal fixation after fracture\n* presence of fistula and\u002For sinus tract or purulent drainage with dehiscence at the incision site\n* at least 2 positive deep tissue cultures or at least 3 positive soft tissue cultures\n* early onset of symptoms (6 weeks)\n* DAIR or implant removal\u002Freplacement due to fracture-related infection\n\nExclusion Criteria:\n\n* Under 18 years old patients\n* prosthetic joint infection\n* only conservative treatment applied\n* pathological fracture due to primary bone tumor\n* simultaneous infection foci in the same extremity\n* fracture-related infection not confirmed by international consensus criteria\n* poor reduction after internal fixation\n* inappropriate or inadequate internal fixation\n* radiological images less than 1 year old\n* findings starting late (after 6 weeks)","ALL","18 Years",{"count":57,"type":58},75,"ESTIMATED","OBSERVATIONAL","This study aims to compare the clinical outcomes of debridement, antibiotics, and implant retention (DAIR) and implant removal\u002Freplacement methods used in the treatment of fracture-related infections, and to determine the infection-free fracture healing rates and the factors affecting treatment success.",[62,63,64,65,66],"Orthopedic Surgery","Fracture Related Infection","Debridement","Implant Retention","Implant Removal\u002FReplacement",[68,69,70,71,22],"orthopedic surgery","fracture-related infection","debridement","implant retention","2026-06-22",{"date":74,"type":75},"2026-06-25","ACTUAL",{"date":77,"type":75},"2026-04-16",{"date":79,"type":58},"2026-06-30",{"name":5,"class":6},1]