[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621296":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":37,"locations":43,"responsibleParty":59,"collaborators":41,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":41,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":41,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":83,"overallStatus":45,"whyStopped":41,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Metropolitan College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Genotype-Based Dietary Counseling","EXPERIMENTAL","Participants in this arm will receive dietary counseling tailored according to their genetic profile. Dietary recommendations will be provided by qualified nutrition professionals and will be based on individual genetic information in combination with standard nutritional principles. The counseling will be delivered over the course of the intervention period.",[13],"Behavioral: Genotype-Based Dietary Counseling",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Dietary Counseling","ACTIVE_COMPARATOR","Participants in this arm will receive dietary counseling based on general dietary guidelines and standard nutritional recommendations. Counseling will be provided by qualified nutrition professionals over the course of the intervention period, without the use of genetic information.",[19],"Behavioral: Standard Dietary Counseling",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","This intervention consists of dietary counseling informed by individual genetic information. Nutrition guidance is provided by qualified nutrition professionals and aims to support weight management and reduction of body fat over the intervention period.",[9],[26],"Nutrigenetic dietary counseling",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"This intervention consists of dietary counseling based on general dietary guidelines and standard nutrition recommendations. Counseling is delivered by qualified nutrition professionals without the use of genetic information.",[15],[31],"General dietary recommendations",[33],{"name":34,"affiliation":35,"role":36},"Angeliki Kapellou, PhD","Dietetics Department, School of Health Sciences, Metropolitan College","PRINCIPAL_INVESTIGATOR",[38],{"name":34,"role":39,"phone":40,"phoneExt":41,"email":42},"CONTACT","+30 6938406218",null,"akapellou@mitropolitiko.edu.gr",[44],{"facility":35,"status":45,"city":46,"state":41,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Marousi","151 25","Greece","GR",{"type":51,"coordinates":52},"Point",[53,54],23.8,38.05,{"lat":54,"lon":53},[57],{"name":34,"role":39,"phone":58,"phoneExt":41,"email":42},"+30 21 3333 0300",{"type":36,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":41,"oldOrganization":41},"Angeliki Kapellou","Principal Investigator","100621296","comparison-of-genotype-based-dietary-counseling-versus-standard-dietary-counseling-on-weight-loss-and-fat-mass-reduction-100621296",false,"NCT07368777","Comparison of Genotype-Based Dietary Counseling Versus Standard Dietary Counseling on Weight Loss and Fat Mass Reduction","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Body mass index (BMI) ≥25 kg\u002Fm²\n* Greek-speaking (able to read and understand Greek and provide informed consent)\n* Willing and able to participate in dietary counseling and study assessments for the duration of the study\n\nExclusion Criteria:\n\n* Current use of pharmacological treatments for weight loss, including but not limited to GLP-1 receptor agonists, appetite suppressants, or other anti-obesity medications\n* Participation in any structured weight-loss intervention or program within the previous 3 months, including commercial weight-loss programs or medically supervised dietary interventions\n* Use of medications known to significantly affect body weight or body composition, such as systemic corticosteroids, antipsychotic medications, or medications for thyroid disorders\n* Pregnancy or lactation\n* Presence of medical conditions that may affect body weight, metabolism, or nutritional status, including untreated thyroid disease, severe gastrointestinal disorders, or endocrine disorders",true,"ALL","18 Years","65 Years",{"count":73,"type":74},88,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study aims to compare the effects of genotype-based dietary counseling with standard dietary counseling based on general recommendations on weight loss and reduction of body fat. Participants will receive individualized dietary guidance either informed by genetic information or based on conventional dietary guidelines. Changes in body weight and body composition will be assessed over the course of the intervention.",[80,81,82],"Overweight","Overweight and Obesity","Adiposity",[84,85,86,87],"genotype-based nutrition","dietary counseling","weight loss","nutrigenetics","2026-01-26",{"date":90,"type":91},"2026-01-28","ACTUAL",{"date":93,"type":91},"2025-12-15",{"date":95,"type":74},"2027-03",{"name":5,"class":6},1]