[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632006":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":25,"centralContacts":25,"locations":25,"responsibleParty":26,"collaborators":25,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":34,"acronym":25,"eligibilityCriteria":35,"healthyVolunteers":32,"sex":36,"minAge":37,"maxAge":38,"enrollmentInfo":39,"targetDuration":25,"studyType":42,"phases":43,"briefSummary":45,"conditions":46,"keywords":25,"overallStatus":48,"whyStopped":25,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":25},{"fullName":5,"class":6},"West China Second University Hospital","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Group A","During the examination, traditional optical colposcopy (magnification: 7.5-15×) was first used for observation and image acquisition, followed by endoscopy (preset magnification: 90-120×).",[12],"Device: high-definition electronic magnifying endoscopy combined with image-enhanced technology",{"label":14,"type":6,"description":15,"interventionNames":16},"Group B","During the examination, endoscopy was performed first, followed by colposcopy.",[12],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"DEVICE","high-definition electronic magnifying endoscopy combined with image-enhanced technology","High-definition magnifying endoscopy (100-150×) enables clear visualization of microvascular and mucosal structures. In recent years, magnifying endoscopy combined with image-enhanced techniques (such as NBI\u002FBLI\u002FLCI) has established a well-developed vascular and epithelial interpretation system for the diagnosis of early esophageal squamous cell carcinoma. The cervix, vagina, and esophagus share the same stratified squamous epithelium, and the pathological evolution of precancerous lesions and early cancer exhibits similarities. Therefore, this technical framework may theoretically be transferable to the detection of lower genital tract lesions.",[9,14],[24],"Traditional Colposcopy",null,{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Shengtao Zhou","Chief Physician","100632006","comparison-of-high-definition-electronic-magnifying-endoscopy-with-image-enhanced-technology-versus-colposcopy-in-the-detection-of-cervical-and-vaginal-lesions-100632006",false,"NCT07508072","Comparison of High-Definition Electronic Magnifying Endoscopy With Image-Enhanced Technology Versus Colposcopy in the Detection of Cervical and Vaginal Lesions","Inclusion Criteria:\n\n* ① Aged 18-65 years, with indications for colposcopy (HPV16\u002F18 positive; HPV non-16\u002F18 positive with LCT ≥ ASCUS; HPV negative with LCT ≥ LSIL; persistent HPV infection ≥ 1 year).\n\n  * Voluntarily sign the informed consent form.\n\nExclusion Criteria:\n\n* ① Women who are pregnant or breastfeeding.\n\n  * Acute reproductive tract infection, severe coagulation disorders. ③ History of radiotherapy for malignant tumors, study participants with severe mental illness.\n\n    * Underage women.","FEMALE","18 Years","65 Years",{"count":40,"type":41},270,"ESTIMATED","INTERVENTIONAL",[44],"NA","1. Primary Objective:\n\n   To compare the diagnostic accuracy of high-definition electronic magnifying endoscopy combined with image-enhanced technology versus colposcopy for cervical and vaginal lesions.\n2. Secondary Objectives:\n\nTo evaluate and compare the sensitivity, specificity, positive predictive value, and negative predictive value of the two examination methods, and to assess the differences between the two techniques in image characteristics, such as lesion border clarity and visualization of microvascular structures.",[47],"Cervical Disease","NOT_YET_RECRUITING","2026-03-27",{"date":51,"type":52},"2026-04-02","ACTUAL",{"date":54,"type":41},"2026-03-28",{"date":56,"type":41},"2030-03-28",{"name":5,"class":6}]