[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605921":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":43,"centralContacts":44,"locations":52,"responsibleParty":63,"collaborators":43,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":43,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":43,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":90,"whyStopped":43,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Al-Azhar University","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Hyaluronic acid","EXPERIMENTAL","• After achieving complete hemostasis: Mix HA (0,5% gengigel teething) with ZO powder until a mixture, then apply it on pulp stumps.\n\nall teeth will be restored with glass ionomer (Prevest Denpro Micron Superior Limited, India),then a stainless steel crown (3M, ESPE, USA) to ensure proper coronal seal and long-term success, which was cemented by glass ionomer cement(Prevest Denpro Micron Luting Limited, India).",[13],"Procedure: Hyaluronic Acid (HA)",{"label":15,"type":10,"description":16,"interventionNames":17},"TheraCal","• After achieving complete hemostasis: TheraCal L.C will be applied directly to the radicular pulp by a disposable syringe tip and light cure will be done for 20 seconds.\n\nall teeth will be restored with glass ionomer (Prevest Denpro Micron Superior Limited, India),then a stainless steel crown (3M, ESPE, USA) to ensure proper coronal seal and long-term success, which was cemented by glass ionomer cement(Prevest Denpro Micron Luting Limited, India).",[18],"Procedure: TheraCal",{"label":20,"type":21,"description":22,"interventionNames":23},"Mineral Trioxide Aggregate","ACTIVE_COMPARATOR","• After achieving complete hemostasis: mix MTA with sterile saline and put on pulp stumps. A moist cotton pellet was placed for initial setting.\n\nall teeth will be restored with glass ionomer (Prevest Denpro Micron Superior Limited, India),then a stainless steel crown (3M, ESPE, USA) to ensure proper coronal seal and long-term success, which was cemented by glass ionomer cement(Prevest Denpro Micron Luting Limited, India).",[24],"Procedure: Mineral Trioxide Aggregate",[26,33,38],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"PROCEDURE","Hyaluronic Acid (HA)","• After achieving complete hemostasis:\n\n1. Mix HA (0,5% gengigel teething) with ZO powder until a mixture, then apply it on pulp stumps.\n2. all teeth will be restored with glass ionomer (Prevest Denpro Micron Superior Limited, India),then a stainless steel crown (3M, ESPE, USA) to ensure proper coronal seal and long-term success, which was cemented by glass ionomer cement(Prevest Denpro Micron Luting Limited, India)",[9],[32],"HA Pulpotomy",{"type":27,"name":15,"description":34,"armGroupLabels":35,"otherNames":36},"• After achieving complete hemostasis:\n\n1. TheraCal L.C will be applied directly to the radicular pulp by a disposable syringe tip and light cure will be done for 20 seconds.\n2. all teeth will be restored with glass ionomer (Prevest Denpro Micron Superior Limited, India),then a stainless steel crown (3M, ESPE, USA) to ensure proper coronal seal and long-term success, which was cemented by glass ionomer cement(Prevest Denpro Micron Luting Limited, India)",[15],[37],"TheraCal LC Pulpotomy",{"type":27,"name":20,"description":39,"armGroupLabels":40,"otherNames":41},"• After achieving complete hemostasis:\n\n1. mix MTA with sterile saline and put on pulp stumps. A moist cotton pellet was placed for initial setting.\n2. all teeth will be restored with glass ionomer (Prevest Denpro Micron Superior Limited, India),then a stainless steel crown (3M, ESPE, USA) to ensure proper coronal seal and long-term success, which was cemented by glass ionomer cement(Prevest Denpro Micron Luting Limited, India)",[20],[42],"MTA Pulpotomy",null,[45,50],{"name":46,"role":47,"phone":48,"phoneExt":43,"email":49},"Omaima Salah Elbeltagy","CONTACT","00201159514617","Elbeltagyomaima@gmail.com",{"name":51,"role":47,"phone":43,"phoneExt":43,"email":43},"Dr. Adel Fathy Hussein, Professor",[53],{"facility":5,"status":43,"city":54,"state":43,"zip":43,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":43},"Cairo","Egypt","EG",{"type":58,"coordinates":59},"Point",[60,61],31.24967,30.06263,{"lat":61,"lon":60},{"type":64,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":43,"oldOrganization":43},"PRINCIPAL_INVESTIGATOR","Omaima Salah Ahmed Mohamed Elbeltagy","Doctor","100605921","comparison-of-hyaluronic-acid-theracal-and-mineral-trioxide-aggregate-as-pulpotomy-agents-in-primary-molars-100605921",false,"NCT07168811","Comparison of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary Molars","Comparative Clinical and Radiographic Evaluation of Hyaluronic Acid, TheraCal, and Mineral Trioxide Aggregate as Pulpotomy Agents in Primary Molars: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Age 4-8 years,\n* Co-operative patient\n* At least one restorable mandibular second primary molars with deep carious lesions requiring pulpotomy.\n* Absence of gingival swelling or sinus tract.\n* Absence of spontaneous pain.\n* Absence of pain on percussion.\n* Controlled bleeding.\n* First treatment the tooth.\n* Possibility of restoring the tooth with a stainless steel crown.\n* No Radiographic evidence of changes associated with pulp degeneration, such as widening of PDL space, internal root resorption, external root resorption, inter-radicular or periapical bone destruction (radiolucency).\n\nExclusion Criteria:\n\n* Swelling, sinus tract, or fistula.\n* Spontaneous pain.\n* Necrotic pulp, pathological mobility.\n* Cases require for general anesthesia.\n* A history of repeated need for analgesics.\n* Patients with any systemic diseases.\n* Uncontrolled bleeding.\n* Selected deciduous teeth without a permanent successor","ALL","4 Years","8 Years",{"count":78,"type":79},66,"ESTIMATED","INTERVENTIONAL",[82],"NA","This randomized clinical trial aims to evaluation the clinical and radiographic outcomes of hyaluronic acid, TheraCal, and Mineral Trioxide Aggregate (MTA) when used as pulpotomy agents in primary molars.\n\nThe main question it aims to answer is:\n\nIn children with restorable mandibular second primary molars requiring pulpotomy, does the use of hyaluronic acid or TheraCal LC, compared to MTA, result in improved clinical and radiographic success rates over a 12-month follow-up period?",[85,86],"Pulpotomies Primary Teeth","Pulp Disease, Dental",[88,15,89],"Hyaluronic Acid","MTA","NOT_YET_RECRUITING","2025-09-04",{"date":93,"type":94},"2025-09-11","ACTUAL",{"date":96,"type":79},"2025-10-01",{"date":98,"type":79},"2026-11-01",{"name":5,"class":6},1]