[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612758":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":10,"centralContacts":40,"locations":46,"responsibleParty":62,"collaborators":10,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":10,"studyType":80,"phases":10,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":49,"whyStopped":10,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Karadeniz Technical University","OTHER",[8,16,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Intravenous Analgesia Group (IV)",null,"Participants who receive routine postoperative intravenous analgesia (opioid and\u002For non-opioid medications) as determined by the clinical anesthesia team. No protocol-assigned intervention is applied; analgesia is selected based on routine clinical practice.",[13,14,15],"Other: Intravenous Analgesia","Other: Thoracic Epidural Analgesia (TEA)","Other: Erector Spinae Plane Block (ESPB)",{"label":17,"type":10,"description":18,"interventionNames":19},"Thoracic Epidural Analgesia Group (TEA)","Participants who receive thoracic epidural analgesia via an epidural catheter placed preoperatively for postoperative pain control. TEA is administered according to institutional routine practice and is not assigned by the study protocol",[13,14,15],{"label":21,"type":10,"description":22,"interventionNames":23},"Erector Spinae Plane Block Group (ESPB)","Participants who receive bilateral erector spinae plane block (ESPB) performed preoperatively for postoperative analgesia. This block is a routine clinical procedure and is not assigned or modified by the study protocol.",[13,14,15],[25,32,36],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":29},"Intravenous Analgesia","Routine postoperative intravenous analgesia (opioid and\u002For non-opioid medications) administered according to standard clinical care. This is not assigned by protocol and represents usual practice.",[21,9,17],[30,31],"IV Analgesia","Intravenous Pain Management",{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":10},"Thoracic Epidural Analgesia (TEA)","Thoracic epidural catheterization performed as part of routine postoperative analgesia management. This practice is determined by the clinical anesthesia team and not assigned by the study protocol.",[21,9,17],{"type":6,"name":37,"description":38,"armGroupLabels":39,"otherNames":10},"Erector Spinae Plane Block (ESPB)","Bilateral erector spinae plane block performed preoperatively as part of routine perioperative analgesia. The technique is applied at the discretion of the clinical anesthesia team and is not protocol-assigned.",[21,9,17],[41],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"Ali AKDOGAN, MD","CONTACT","+905322605414","draliakdogan@yahoo.com",[47],{"facility":48,"status":49,"city":50,"state":50,"zip":10,"country":51,"countryCode":10,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Karadeniz Technical University Farabi Hospital","RECRUITING","Trabzon","Turkey (Türkiye)",{"type":53,"coordinates":54},"Point",[55,56],39.72694,41.005,{"lat":56,"lon":55},[59],{"name":60,"role":43,"phone":61,"phoneExt":10,"email":45},"Ali Akdoğan","05322605414",{"type":63,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ali AKDOĞAN","Associate Professor of Anesthesiology and Reanimation","100612758","comparison-of-iv-analgesia-thoracic-epidural-analgesia-and-esp-block-for-chronic-pain-after-open-heart-surgery-100612758",false,"NCT07257744","Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery","A Comparative Evaluation of Intravenous Analgesia, Thoracic Epidural Analgesia, and Erector Spinae Plane Block on Chronic Postoperative Pain Following Open Heart Surgery","TEA-ESPB-IV","Inclusion Criteria:\n\n* Adults aged 18 to 85 years\n* Classified as ASA physical status I-III\n* Scheduled to undergo open heart surgery with median sternotomy\n* BMI \\\u003C 35 kg\u002Fm²\n* Able to understand and provide written informed consent\n* Eligible to receive any of the routine analgesia methods (intravenous analgesia, thoracic epidural analgesia, or erector spinae plane block)\n\nExclusion Criteria:\n\n* Age \\\u003C 18 or \\> 85 years\n* BMI ≥ 35 kg\u002Fm²\n* Coagulation disorders\n* Infection at the intervention site\n* Known allergy to local anesthetics or induction agents\n* Psychiatric disorders limiting cooperation\n* Use of chronic pain medications, antidepressants, corticosteroids, antiepileptics, or routine analgesics\n* Inability to cooperate, communicate, or follow commands\n* Physical or verbal performance impairment\n* Previous open heart surgery","ALL","18 Years","85 Years",{"count":78,"type":79},90,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral erector spinae plane block (ESPB). The primary objective is to evaluate the impact of these analgesia modalities on the development of chronic postoperative pain at 3 months. Secondary objectives include assessing postoperative acute pain scores, additional analgesic requirements, extubation time, mobilization time, intensive care unit stay, hospital stay, respiratory complications, and the relationship between acute and chronic pain. No intervention is assigned by protocol, and all analgesia methods are applied as part of routine clinical practice.",[83,84,85,86],"Chronic Postoperative Pain","Open Heart Surgery","Postoperative Analgesia","Analgesia",[84,83,88,33,37,89,90],"Post-Sternotomy Pain","Pain Management","Cardiac Anesthesia","2025-11-27",{"date":93,"type":94},"2025-12-02","ACTUAL",{"date":96,"type":94},"2025-02-15",{"date":98,"type":79},"2026-04-20",{"name":5,"class":6},1]