[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100528949":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":26,"responsibleParty":44,"collaborators":47,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":26,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":83,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":26},{"fullName":5,"class":6},"Fudan University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Kimura group","EXPERIMENTAL","Laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique.",[13],"Procedure: Laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique",{"label":15,"type":16,"description":17,"interventionNames":18},"Warshaw group","ACTIVE_COMPARATOR","Laparoscopic spleen-preserving distal pancreatectomy using the Warshaw technique.",[19],"Procedure: Laparoscopic spleen-preserving distal pancreatectomy using the Warshaw technique",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique","The laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique is defined as a surgical procedure that aims to remove the distal part of the pancreas while preserving the spleen by maintaining the splenic artery and vein (Hepatogastroenterology. 2003;50:2242).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Laparoscopic spleen-preserving distal pancreatectomy using the Warshaw technique","Warshaw technique laparoscopic spleen-preserving distal pancreatectomy is defined as a surgical procedure that aims to preserve the spleen while removing the distal part of the pancreas. It involves ligating the splenic artery and vein, while preserving the left gastroepiploic artery and short gastric vessels (Arch Surg. 1988;123:550).",[15],[32],{"name":33,"affiliation":5,"role":34},"Xianjun Yu, MD, PhD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+86-13801669875","yuxianjun@fudanpci.org",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Zheng Li, MD","+86-18521097686","lizheng@fudanpci.org",{"type":34,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Xian-Jun Yu","President of Fudan University Shanghai Cancer Center",[48,50,52,54],{"name":49,"class":6},"Tianjin Medical University Cancer Institute and Hospital",{"name":51,"class":6},"Qilu Hospital of Shandong University",{"name":53,"class":6},"The Third Affiliated Hospital of Soochow University",{"name":55,"class":6},"Tongji Hospital","100528949","comparison-of-kimura-versus-warshaw-technique-for-laparoscopic-spleen-preserving-distal-pancreatectomy-100528949",false,"NCT06167421","Comparison of Kimura Versus Warshaw Technique for Laparoscopic Spleen-Preserving Distal Pancreatectomy","Comparison of Kimura Versus Warshaw Technique for Laparoscopic Spleen-Preserving Distal Pancreatectomy: A Multicenter Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Age between 18 and 70 years, regardless of gender.\n* Preoperative clinical diagnosis of benign or low-grade malignant pancreatic tumors.\n* Meeting the recommended surgical indications as per guidelines.\n* Feasibility of imaging assessment for either Kimura or Warshaw technique laparoscopic spleen-preserving distal pancreatectomy.\n* Performance status of 0 or 1 according to the Eastern Cooperative Oncology Group (ECOG) score.\n* Willingness to comply with the study treatment plan, follow-up schedule, and other protocol requirements.\n* Voluntarily participating in the study and signing an informed consent form.\n\nExclusion Criteria:\n\n* Body Mass Index (BMI) \\> 28 kg\u002Fm2 (Chinese obesity standard).\n* History of blood disorders, acute or chronic pancreatitis, gastrointestinal bleeding, splenic rupture, or gastric varices (preoperative CT indicating curved vessel structures along the gastric wall with a diameter \\> 5mm).\n* History of abdominal surgery.\n* Concomitant primary malignant tumors.\n* Suspicion of malignancy based on PET-CT or other imaging examinations.\n* Severe impairment of cardiac, liver, or kidney function (NYHA class 3-4, ALT and\u002For AST exceeding three times the upper limit of normal, Creatinine exceeding the upper limit of normal).\n* Planned pregnancy or pregnancy and lactating women.\n* Participants currently involved in other clinical trials.","ALL","18 Years","70 Years",{"count":67,"type":68},240,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study aims to compare the surgical outcomes of laparoscopic spleen-preserving distal pancreatectomy using the Kimura technique versus the Warshaw technique. The primary focus is on the rates of unplanned splenectomy, occurrence of severe complications, as well as intraoperative and perioperative outcomes of both techniques.",[74,75,76],"Pancreatic Tumor, Benign","Pancreatic Neuroendocrine Tumor","Solid Pseudopapillary Tumor of the Pancreas",[78,79,80,81,82],"Pancreatic benign or low-grade malignant tumors","Minimally invasive spleen-preserving distal pancreatectomy","Kimura technique","Warshaw technique","Prognosis","NOT_YET_RECRUITING","2023-12-04",{"date":86,"type":87},"2023-12-12","ACTUAL",{"date":89,"type":68},"2024-01-01",{"date":91,"type":68},"2027-12-31",{"name":5,"class":6}]