[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608765":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":41,"responsibleParty":57,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":26,"maxAge":26,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":78,"overallStatus":83,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Pakistan Institute of Medical Sciences","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I: Bioceramic sealer + Bioceramic coated GP)","EXPERIMENTAL","Extracted single-rooted teeth obturated with bioceramic-coated gutta-percha in combination with a bioceramic sealer. This arm evaluates the sealing ability of the newer coated obturation material.",[13],"Procedure: bioceramic coated gutta percha",{"label":15,"type":16,"description":17,"interventionNames":18},"Group II (Bioceramic sealer + conventional (non-coated) GP)","ACTIVE_COMPARATOR","Extracted single-rooted teeth obturated with conventional (non-coated) gutta-percha in combination with a bioceramic sealer. This arm serves as the reference\u002Fcontrol to compare sealing ability against the experimental mate",[19],"Procedure: conventional(non-coated) gutta percha",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","bioceramic coated gutta percha","Experimental Arm (Bioceramic-coated GP + Bioceramic Sealer):\n\nSpecimens will be obturated using bioceramic-coated gutta-percha cones in combination with bioceramic sealer after canal preparation with ProTaper NEXT files up to size F3.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"conventional(non-coated) gutta percha","Active Comparator Arm (Conventional GP + Bioceramic Sealer):\n\nSpecimens will be obturated using conventional (non-coated) gutta-percha cones in combination with the same bioceramic sealer after canal preparation with ProTaper NEXT files up to size F3.",[15],[32],{"name":33,"affiliation":34,"role":35},"Amna Amir, BDS","School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad.","PRINCIPAL_INVESTIGATOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+92 335 0437279","amiramna351@gmail.com",[42],{"facility":43,"status":26,"city":44,"state":26,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad","Islamabad","52000","Pakistan","PK",{"type":49,"coordinates":50},"Point",[51,52],73.04329,33.72148,{"lat":52,"lon":51},[55,56],{"name":33,"role":38,"phone":26,"phoneExt":26,"email":40},{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"type":35,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Amna Amir","Principal Investigator","100608765","comparison-of-leakage-in-endodontically-treated-teeth-obturated-with-different-types-of-gutta-percha-coatings-and-bioceramic-sealer-100608765",false,"NCT07205809","Comparison of Leakage in Endodontically Treated Teeth Obturated With Different Types of Gutta Percha Coatings and Bioceramic Sealer","In Vitro Comparison of Leakage in Endodontically Treated Teeth Obturated With Different Types of GP Coatings Using Bioceramic Sealer: A Randomized Controlled Trial.","Inclusion Criteria:\n\n1\\. Extracted human teeth with single canal and mature root apex\n\nExclusion Criteria:\n\n1. Teeth with calcified (non-negotiable) canals.\n2. Teeth with internal\u002Fexternal root resorption (as seen on radiograph)\n3. Teeth with caries extending to the floor of pulp chamber.\n4. Teeth with a single canal but open apex.",true,"ALL",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","In vitro study to compare the sealing ability of bioceramic-coated gutta-percha with bioceramic sealer against conventional gutta-percha with bioceramic sealer in root canal obturation. A total of 60 extracted human single-canal teeth will be prepared and obturated according to standardized protocols, then evaluated for microleakage. Data will be analyzed using SPSS (version 25) with appropriate non-parametric tests at a significance level of p\\\u003C0.05. The outcomes are expected to identify the more effective obturation material combination in achieving a fluid-tight seal, thereby contributing to improved success rates in endodontic therapy.",[77],"Leakage Testing",[79,80,81,82],"leakage","gutta percha","bioceramic","sealer","NOT_YET_RECRUITING","2025-09-26",{"date":86,"type":87},"2025-10-03","ACTUAL",{"date":89,"type":71},"2025-11-05",{"date":91,"type":71},"2026-06-12",{"name":5,"class":6},1]