[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618890":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":52,"collaborators":10,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":10,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":10,"enrollmentInfo":64,"targetDuration":10,"studyType":67,"phases":10,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"200 subjects: healthy volunteers and patients scheduled for orthopedic and cardiothoracic surgery",null,"Two hundred subjects will include healthy volunteer individuals, employees of the Galeazzi-Sant'Ambrogio Hospital, and patients at the time of pre-admission or admission who are scheduled for major orthopedic surgery involving hip or knee prostheses, or for cardiothoracic surgery, as these represent the largest cohorts within our institution. All subjects will be older than 18y, without cancer, obesity, not pregnant, and able to understand or make decisions.",[13],"Other: blood sampling",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"blood sampling","No intervention, besides blood sampling for 25-(OH) vitamin D quantification, is required since this study intends to assess the agreement among the results obtained using the Maglumi X3 SNIBE method and other analytical methods for the measurement of 25-(OH) vitamin D.",[9],[20],{"name":21,"affiliation":22,"role":23},"Giovanni Lombardi, PhD","IRCCS Ospedale Galeazzi-Sant'Ambrogio","PRINCIPAL_INVESTIGATOR",[25,29],{"name":21,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","+390283502222","giovanni.lombardi@grupposandonato.it",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Martina Faraldi, PhD","+390283502248","martina.faraldi@grupposandonato.it",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Laboratory of Experimental Biochemistry and Advanced Diagnostic","RECRUITING","Milan","Milano","20175","Italy","IT",{"type":43,"coordinates":44},"Point",[45,46],12.59836,42.78235,{"lat":46,"lon":45},[49,50,51],{"name":21,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},{"name":21,"role":23,"phone":10,"phoneExt":10,"email":10},{"type":53,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100618890","comparison-of-maglumi-x3-snibe-with-other-analytical-methods-in-laboratory-medicine-for-25-ohd-quantification-100618890",false,"NCT07337499","Comparison of Maglumi X3 SNIBE With Other Analytical Methods in Laboratory Medicine for 25-(OH)D Quantification","Comparison of the Maglumi X3 SNIBE Method With Other Analytical Methods in Laboratory Medicine","Inclusion Criteria:\n\n* Healthy volunteer subjects:\n\nSubjects who sign the informed consent to participate in the study Age ≥ 18 years Employees, in various roles, of the IRCCS Galeazzi-Sant'Ambrogio Hospital\n\n-Patients:\n\nSubjects who sign the informed consent to participate in the study Age ≥ 18 years Patients referred for major orthopedic surgery: hip and knee replacement (bicompartmental and unicompartmental) Patients referred for cardiothoracic surgery\n\nExclusion Criteria:\n\n* Neoplastic diseases (until remission)\n* Grade I, II, and III obesity\n* Age \\\u003C 18 years\n* Women who are pregnant or breastfeeding, based on self-declaration\n* Individuals unable to understand and make decisions",true,"ALL","18 Years",{"count":65,"type":66},200,"ESTIMATED","OBSERVATIONAL","The aim of this study is to assess the agreement among the results obtained using the Maglumi X3 SNIBE method and other analytical methods for the measurement of 25-(OH) vitamin D. The comparison between analytical methods is essential for evaluating the analytical performance of different measurement techniques. Assessing the level of comparability between measurements of the same analyte obtained using different methods is fundamental for the harmonization and quality of procedures used in laboratory medicine, ensuring a correct clinical interpretation of results.",[70],"Quantification of 25-(OH)D in Physiological Condition",[72,73,74,75],"25-(OH)D","vitamin D","analytical methods","immunoassay","2026-01-02",{"date":78,"type":79},"2026-01-13","ACTUAL",{"date":81,"type":79},"2025-09-15",{"date":83,"type":66},"2026-03-31",{"name":5,"class":6},1]