[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636152":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":11,"locations":27,"responsibleParty":68,"collaborators":11,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":72,"sex":78,"minAge":79,"maxAge":11,"enrollmentInfo":80,"targetDuration":11,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":30,"whyStopped":11,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Propofol maintenance","ACTIVE_COMPARATOR",null,[13],"Other: Maintenance of general anesthesia by Propofol",{"label":15,"type":16,"description":11,"interventionNames":17},"Sevoflurane maintenance","EXPERIMENTAL",[18],"Other: Maintenance of general anesthesia by Sevoflurane",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Maintenance of general anesthesia by Propofol","Maintenance of general anesthesia for simple electrophysiological procedures",[9],{"type":6,"name":25,"description":22,"armGroupLabels":26,"otherNames":11},"Maintenance of general anesthesia by Sevoflurane",[15],[28],{"facility":29,"status":30,"city":31,"state":11,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Cliniques universitaires Saint-Luc","RECRUITING","Brussels","1200","Belgium","BE",{"type":36,"coordinates":37},"Point",[38,39],4.34878,50.85045,{"lat":39,"lon":38},[42,47,49,52,54,56,58,60,62,64,66],{"name":43,"role":44,"phone":45,"phoneExt":11,"email":46},"Céline Khalifa, MD PhD","CONTACT","+3227641821","celine.khalifa@saintluc.uclouvain.be",{"name":48,"role":44,"phone":45,"phoneExt":11,"email":11},"Laetitia Miltoni, MD",{"name":50,"role":51,"phone":11,"phoneExt":11,"email":11},"Christine Watremez, MD PhD","SUB_INVESTIGATOR",{"name":53,"role":51,"phone":11,"phoneExt":11,"email":11},"Mona Momeni, MD PhD",{"name":55,"role":51,"phone":11,"phoneExt":11,"email":11},"David Kahn, MD",{"name":43,"role":57,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"name":59,"role":51,"phone":11,"phoneExt":11,"email":11},"Robert Tircoveanu, MD",{"name":61,"role":51,"phone":11,"phoneExt":11,"email":11},"Aurélie Jacobs Sariyar, MD",{"name":63,"role":51,"phone":11,"phoneExt":11,"email":11},"Maximilien Cappe, MD",{"name":65,"role":51,"phone":11,"phoneExt":11,"email":11},"Lina Puodzukaite, MD",{"name":67,"role":51,"phone":11,"phoneExt":11,"email":11},"Guillaume Lemaire, MD",{"type":69,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100636152","comparison-of-maintenance-of-propofol-and-sevoflurane-spectral-study-100636152",false,"NCT07561970","COmparison of Maintenance of Propofol And Sevoflurane Spectral Study","Comparison of EEG Power Spectrum During Maintenance of Anesthesia With Propofol Versus Sevoflurane","COMPASS","Inclusion Criteria: Adult patients undergoing elective electrophysiological interventions, such as atrial fibrillation ablation procedures, under general anesthesia\n\n* Capable to give informed consent\n* French-speaking patients\n\nExclusion Criteria:\n\n* Need for a premedication with benzodiazepine before anesthesia\n* Reduced left ventricular ejection fraction (\\\u003C 50%) or underlying cardiac pathology requiring a more balanced anesthesia (administration of benzodiazepine and\u002For ketamine during anesthesia)\n* Preoperative MoCA score \\\u003C 26\u002F30 (for patients \\> ou = 55 years old)\n* Patients treated with anti-epileptic drugs\n* Patients treated with benzodiazepines (ex: for anxiolysis or sleep disorders)\n* Emergencies\n* Morbid obesity (BMI \\> 40kg\u002Fm2)\n* Background of severe postoperative nausea\u002Fvomit","ALL","18 Years",{"count":81,"type":82},280,"ESTIMATED","INTERVENTIONAL",[85],"NA","Lower EEG alpha band power is currently extensively studied as a potential biomarker of brain vulnerability. No previous study has evaluated whether there was a difference in EEG power spectrum ranges between propofol and sevoflurane, the two main anesthetic agents for maintenance of general anesthesia, in order to define a cut-off value for the prediction of a higher risk of postoperative delirium.\n\n* Primary objective: comparison of EEG alpha power (dB) during maintenance of anesthesia with propofol and sevoflurane using data available in the NeuroSense® depth-of-anesthesia monitoring\n* Secondary objectives: comparison of other EEG frequency bands during maintenance of anesthesia with propofol and sevoflurane using data from the NeuroSense® depth-of-anesthesia monitoring",[88],"Electroencephalography\u002FDrug Effects",[90,91],"intraoperative electroencephalography","alpha-band power","2026-04-24",{"date":94,"type":95},"2026-05-01","ACTUAL",{"date":97,"type":95},"2026-04-13",{"date":99,"type":82},"2027-12",{"name":5,"class":6},1]