[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641218":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":66,"collaborators":26,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":91,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"GCS Ramsay Santé pour l'Enseignement et la Recherche","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"MCI group","EXPERIMENTAL","MCI involves the use of autologous cartilage tissue, which is harvested, minced, and re-implanted in a one-stage surgery to promote chondrogenesis and repair",[13],"Procedure: Minced cartilage implantation - MCI",{"label":15,"type":16,"description":17,"interventionNames":18},"Microfracture group","ACTIVE_COMPARATOR","Microfracture surgery is a surgical technique for repairing joint cartilage",[19],"Procedure: Microfracture",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Minced cartilage implantation - MCI","Autologous minced cartilage will be harvested from the defect site and cam deformity area using a non-aggressive shaver blade . The cartilage will then be collected and augmented with platelet-rich plasma from the patient's blood. The platelet-rich plasma will be 100% autologous. Cautious debridement of the chondral lesion up to the stable chondral margins will be performed, followed by removal of the calcified subchondral bone layer, then the minced cartilage will be implanted on the acetabular chondral lesion using an application cannula.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Microfracture","Microfracture surgery is a surgical technique that works by creating tiny fractures in the underlying bone. This stimulates the growth of new cartilage.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Nicolas BONIN, MD","CONTACT","+ 33 4 72 20 00 00","dr.bonin@lyon-ortho-clinic.com",[38,52],{"facility":39,"status":26,"city":40,"state":26,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Clinique De La Sauvegarde","Lyon","69009","France","FR",{"type":45,"coordinates":46},"Point",[47,48],4.84789,45.74906,{"lat":48,"lon":47},[51],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"facility":53,"status":26,"city":54,"state":26,"zip":55,"country":42,"countryCode":43,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"ICOSS","Strasbourg","67100",{"type":45,"coordinates":57},[58,59],7.74553,48.58392,{"lat":59,"lon":58},[62],{"name":63,"role":34,"phone":64,"phoneExt":26,"email":65},"Michel RAHME, MD","+33 6 84 49 41 20","dr.mrahme@gmail.com",{"type":67,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100641218","comparison-of-minced-cartilage-implantation-versus-microfracture-for-acetabular-chondral-lesions-due-to-fai-femoro-acetabular-impingement-100641218",false,"NCT07657871","Comparison of Minced Cartilage Implantation Versus Microfracture for Acetabular Chondral Lesions Due to FAI (Femoro-acetabular Impingement)","CARTIFRAC","Inclusion Criteria:\n\n* Patient, male or female, aged 18-50 years old;\n* Patient with an acetabular chondral lesion due to FAI, characterised as Beck class 4 or 5, measuring 1-6 cm2;\n* Patient with Tönnis grade 0-2;\n* Patient who signed the informed consent form and is willing to comply with the protocol requirements based on the investigator's judgment;\n* Patient affiliated with a social security scheme;\n* Patient able to answer questionnaires and to communicate freely in French\n\nExclusion Criteria:\n\n* Patient with prior ipsilateral hip surgery;\n* Patient with borderline or frank hip dysplasia (lateral centre edge angle \\\u003C25º);\n* Patient with hyperlaxity (Beighton score \\>7);\n* Patient with any concomitant disease or disorder which, in the opinion of the investigator, may put the patient at risk or may influence the result of the study;\n* Patient that is pregnant or breastfeeding;\n* Patient with protected status under articles L1121-6, LL121-8 and L1122-2 of the French Public Health Code;\n* Patient who cannot comply with the protocol requirements based on the investigator's judgment","ALL","18 Years","50 Years",{"count":79,"type":80},180,"ESTIMATED","INTERVENTIONAL",[83],"NA","A femoroacetabular impingement (FAI) is an abnormal contact between pelvis and the neck of femur. It occurs particularly when patient bends his hip and causes damage to the cartilage. In the long term, FAI can lead to the development of osteoarthritis (cartilage destruction) and may require a total hip replacement (THR).\n\nSurgery to treat cartilage damage in the hip aims to maintain joint function and delay the onset of osteoarthritis. Microfracture remains the most commonly used treatment for cartilage lesions. It is a surgical technique for repairing articular cartilage that works by creating tiny fractures in the bone, which in turn stimulate the growth of new cartilage.\n\nCartilage autografting is a promising alternative to microfracture, offering good results in the knee joint. Cartilage autografting involves the use of autologous cartilage tissue (taken from patient body), which is harvested, ground up and reimplanted in a single surgical procedure to promote the growth of new cartilage and repair.\n\nThe published literature lacks large-scale studies comparing autologous cartilage transplantation with traditional joint-preserving surgeries, such as microfracture. This is the reason why this study is set up.",[86],"Femoro-acetabular Impingement (FAI)",[88,89,90],"FAI","Minced cartilage implantation","microfracture","NOT_YET_RECRUITING","2026-06-13",{"date":94,"type":95},"2026-06-18","ACTUAL",{"date":97,"type":80},"2026-07",{"date":99,"type":80},"2031-06",{"name":5,"class":6},2]