[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575141":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":41,"locations":47,"responsibleParty":64,"collaborators":31,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":31,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":31,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":50,"whyStopped":31,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Semmelweis University","OTHER",[8,15,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Test 1 Guided biofilm therapy in combinaton with Platelet rich fibrine","EXPERIMENTAL","Non surgical treatment performed to clean and decontaminate the intrabony defect, and filled with PRF",[13,14],"Device: Guided biofilm therapy","Procedure: Platelet Rich Fibrin",{"label":16,"type":10,"description":17,"interventionNames":18},"Test 2 Minimally invasive surgical therapy in combination with Platelet rich fibrine","Surgical procedure: Minimal invasive surical approach Platelet rich fibrine chops is used in order to fill the intrabony gap.",[14,19],"Procedure: Minimally Invasive Surgical Technique",{"label":21,"type":22,"description":23,"interventionNames":24},"Control group","ACTIVE_COMPARATOR","The control group patients are treated only with guided biofilm therapy alone",[13],[26,32,37],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DEVICE","Guided biofilm therapy","Use of Airflow Plus powder subgingivally on teeth with deep periodeontal pockets",[21,9],null,{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":31},"PROCEDURE","Platelet Rich Fibrin","Pack Platelet Rich Fibrin chops into the intrabony periodontla defect",[9,16],{"type":33,"name":38,"description":39,"armGroupLabels":40,"otherNames":31},"Minimally Invasive Surgical Technique","Periodontal intrabony defect is treated by minimally invasive surgical intervention",[16],[42],{"name":43,"role":44,"phone":45,"phoneExt":31,"email":46},"Pál Nagy, DMD","CONTACT","+3613185222","kardpali@gmail.com",[48],{"facility":49,"status":50,"city":51,"state":51,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Semmelweis University Department of Periodontology","RECRUITING","Budapest","1088","Hungary","HU",{"type":56,"coordinates":57},"Point",[58,59],19.04045,47.49835,{"lat":59,"lon":58},[62],{"name":63,"role":44,"phone":45,"phoneExt":31,"email":46},"Pal Nagy, DMD",{"type":65,"investigatorFullName":66,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"PRINCIPAL_INVESTIGATOR","Pal Nagy","associate professor","100575141","comparison-of-mist-with-prf-and-gbt-with-prf-in-the-treatment-of-intrabony-periodontal-defect-a-prospective-rct-100575141",false,"NCT06768424","Comparison of MIST With PRF and GBT With PRF in the Treatment of Intrabony Periodontal Defect. A Prospective RCT","Comparison of Minimally Invasive Surgical Therapy in Combination With Platelet Rich Fibrine and Guided Biofilm Therapy Combined With Platelet Rich Fibrine in the Treatment of Solitaire Intrabony Periodontal Defect A Prospective RCT.","Inclusion Criteria:\n\n* solitaire intrabony periodontal defect at least 4 mm\n\nExclusion Criteria:\n\n* Periodontitis with intrabony defect (Intrabony component ≥ 4mm, defect radiological angulation \\> 25°,\n* The patient is able to comply with the study -related procedures (i.e. good level of oral hygiene, follow-up procedures).\n* Patients must not be heavy smokers (\\\u003C5 cigarettes\u002Fday).\n* furcation involvement\n* Full mouth plaque and bleeding scores (FMPS and FMBS) of \\\u003C15% (O'Leary et al. 1972).\n* The patient is able to fully understand the nature of the study, signed informed consent.",true,"ALL","18 Years","65 Years",{"count":80,"type":81},36,"ESTIMATED","INTERVENTIONAL",[84],"NA","The aim is to evaluate in a prospective, randomized, controlled clinical study the healing of a MIST procedure combined with PRF, or GBT combined with PRF. Clinical, radiological evaluation of the regenerative surgical method and the GBT non-surgical therapy in solitaire deep intrabony periodontal defect.",[87],"Intrabony Periodontal Defect",[89,90],"Guided biofilm terapy","Platelet Rich Fibrine","2026-04-25",{"date":93,"type":94},"2026-04-28","ACTUAL",{"date":96,"type":94},"2023-12-20",{"date":98,"type":81},"2027-12-20",{"name":5,"class":6},1]