[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608027":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":25,"responsibleParty":30,"collaborators":25,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":25,"eligibilityCriteria":40,"healthyVolunteers":41,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":25,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":25,"overallStatus":56,"whyStopped":25,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":25},{"fullName":5,"class":6},"Shaheed Zulfiqar Ali Bhutto Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Passive ultrasonic activation","ACTIVE_COMPARATOR","passive ultrasonic irrigant activation will be performed by using a stainless steel ultrasonic Irrisafe file of size 20 (IRRI S 21\u002F25; VDW, Germany) mounted on ultrasonic unit (Woodpecker Ultrasonic Scaler UDS-J). The file will be kept 2 mm short of working length loosely without binding to the canal. 2.5% NaOCl will be activated for 30 seconds by using a power setting of five.",[13],"Procedure: passive ultrasonic activation",{"label":15,"type":10,"description":16,"interventionNames":17},"Sonic activation","In group B, root canals will be filled with 2.5% sodium hypochlorite and medium size tip (red, 25\u002F04) of EndoAcivator (YAHOPE A3, China) will be used keeping it 2 mm short of working length. The activation of irrigant will be done in 2-3 mm vertical strokes for 30 seconds in between each instrumentation",[18],"Procedure: sonic activation",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","passive ultrasonic activation","passive ultrasonic irrigant activation will be performed by using a stainless steel ultrasonic Irrisafe file of size 20 (IRRI S 21\u002F25; VDW, Germany) mounted on ultrasonic unit (Woodpecker Ultrasonic Scaler UDS-J). The file will be kept 2 mm short of working length loosely without binding to the canal. 2.5% NaOCl will be activated for 30 seconds by using a power setting of five",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"sonic activation","root canals will be filled with 2.5% sodium hypochlorite and medium size tip (red, 25\u002F04) of EndoAcivator (YAHOPE A3, China) will be used keeping it 2 mm short of working length. The activation of irrigant will be done in 2-3 mm vertical strokes for 30 seconds in between each instrumentation",[15],{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","RANA AHMAD","Assistant Professor","100608027","comparison-of-post-operative-pain-after-different-root-canal-irrigant-activation-methods-100608027",false,"NCT07196215","Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods","Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods in Maxillary Incisors With Symptomatic Irreversible Pulpitis","Inclusion Criteria:\n\n* • Patients in good health with no systemic disease (ASA Class I or II)\n\n  * Age range is between 20 to 50 years.\n  * Patients diagnosed with symptomatic irreversible pulpitis in maxillary incisor teeth.\n  * Patients who can understand VAS.\n  * Patients who give verbal consent to participate voluntarily in the study.\n\nExclusion Criteria:\n\n* • History of systemic disorder.\n\n  * Pregnant \u002F lactating females (As per medical record\u002Fverbally)\n  * Patients who had taken preoperative drugs as anti-inflammatory analgesic or antibiotics.\n  * Patients with swelling or acute peri-apical abscess.\n  * Tooth not suitable for restoration.\n  * Periodontally compromised teeth.\n  * Retreatment cases.",true,"ALL","20 Years","50 Years",{"count":46,"type":47},72,"ESTIMATED","INTERVENTIONAL",[50],"NA","root canal irrigation protocol",[53,54,55],"Irriversible Pulpitis","Irrigation","Activation, Patient","NOT_YET_RECRUITING","2025-09-26",{"date":59,"type":60},"2025-09-29","ACTUAL",{"date":62,"type":47},"2026-01-01",{"date":64,"type":47},"2027-01-01",{"name":32,"class":6}]