[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622227":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":65,"collaborators":26,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":26,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Lahore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"group A Sensory Re-Education","EXPERIMENTAL","Participants in this group will receive a structured sensory re-education program for six weeks, with three sessions per week. Each session will include 10 minutes of electrical muscle stimulation (EMS) applied to the lower lumbar region and area of neuropathic discomfort. Sensory re-education will involve stroking the affected skin using brushes and various textured materials, progressing from rough to soft textures over five minutes per session. Balance and gait will be assessed using the Berg Balance Scale (BBS) and Dynamic Gait Index (DGI) at baseline, mid-intervention, and post-intervention.",[13],"Behavioral: Sensory Re-Education Program",{"label":15,"type":16,"description":17,"interventionNames":18},"group B Proprioceptive Neuromuscular Training","ACTIVE_COMPARATOR","Participants in this group will undergo a structured proprioceptive neuromuscular training program for six weeks, with three sessions per week. Each session will start with 10 minutes of electrical muscle stimulation (EMS) applied to the lower lumbar region and area of neuropathic discomfort. The main intervention will include balance exercises (bilateral stance, heel raises, single-leg stance with hip flexion, eyes open and closed), strengthening exercises targeting lower limb muscles (quadriceps, hamstrings, lateral thigh), plyometric exercises (single- and double-leg jumps with rotations), and agility drills (figure-eight and directional movements). Each session lasts approximately 30 minutes, and exercises will progress in intensity and complexity based on participant tolerance. Balance and gait outcomes will be measured using the Berg Balance Scale (BBS) and Dynamic Gait Index (DGI) at baseline, mid-intervention, and post-intervention.",[19],"Behavioral: Proprioceptive Neuromuscular Training",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Sensory Re-Education Program","Participants will undergo a six-week sensory re-education program, three sessions per week. Each session includes:\n\nElectrical Muscle Stimulation (EMS): 10 minutes applied to lower lumbar region and area of neuropathic discomfort (pulse width 100-200 µs, frequency 80-100 Hz, intensity as tolerated).\n\nSensory Re-Education: Stroking the affected skin using brushes and textured materials (rough hessian, wool, satin, cotton, fur) for 5 minutes per session, progressing from coarse to soft textures.\n\nBalance and gait will be assessed using the Berg Balance Scale (BBS) and Dynamic Gait Index (DGI) at baseline, mid-intervention (3 weeks), and post-intervention (6 weeks).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Proprioceptive Neuromuscular Training","Participants will receive a structured proprioceptive neuromuscular training program for six weeks, three sessions per week. Each session begins with 10 minutes of electrical muscle stimulation (EMS) applied to the lower lumbar region and area of neuropathic discomfort (pulse width 100-200 µs, frequency 80-100 Hz, intensity as tolerated). The main intervention consists of:\n\nBalance exercises: bilateral stance, heel raises, single-leg stance with opposite hip flexed, performed with eyes open and closed.\n\nStrengthening exercises: targeting lower limb muscles including quadriceps, hamstrings, and lateral thigh using squats and resistance exercises.\n\nPlyometric exercises: single- and double-leg jumps with 90° and 180° rotations to enhance coordination.\n\nAgility drills: figure-eight running and directional movements (forward, backward, lateral) along straight and spiral paths.\n\nEach session lasts approximately 30 minutes, with progressive intensity and complexity based on individual toleran",[15],[32],{"name":33,"affiliation":34,"role":35},"Nimra Zaheer, MSPTN","The University of Lahore, Lahore","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","03235018078","nimrazaheer62@gmail.com",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Montiha Azeem, MSPTN","03479717317","muntahaazeem9@gmail.com",[46],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Shadman Medical Center","RECRUITING","Lahore","Punjab Province","54000","Pakistan","PK",{"type":55,"coordinates":56},"Point",[57,58],74.35071,31.558,{"lat":58,"lon":57},[61,63,64],{"name":62,"role":38,"phone":43,"phoneExt":26,"email":44},"Montiha Azeem",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},{"name":33,"role":35,"phone":26,"phoneExt":26,"email":26},{"type":66,"investigatorFullName":62,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","principal investigator","100622227","comparison-of-proprioceptive-neuromuscular-training-and-sensory-re-education-in-patients-with-diabetic-peripheral-neuropathy-100622227",false,"NCT07380880","Comparison of Proprioceptive Neuromuscular Training and Sensory Re-education in Patients With Diabetic Peripheral Neuropathy","PNF-SR in DPN","Inclusion Criteria:\n\nBoth males and females Diagnosed with Diabetes Mellitus (Type 1 or Type 2) Aged between 40-75 years Presence of diabetic peripheral neuropathy (as confirmed by Michigan Neuropathy Assessment Tool or Toronto Clinical Rating Scale) HbA1c level \\> 7% consistently over the last 6 months\n\nExclusion Criteria:\n\nUnable to ambulate independently or with assistance Any history of neurological disorders Any history of musculoskeletal disordersin the past 6 months Renal and liver failure History of Ischemic heart disease History of dizziness or balance-impairing conditions","ALL","40 Years","75 Years",{"count":79,"type":80},80,"ESTIMATED","INTERVENTIONAL",[83],"NA","Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus and is associated with sensory loss, impaired proprioception, balance deficits, and altered gait patterns, which significantly increase the risk of falls and functional dependence. Rehabilitation strategies targeting sensory and proprioceptive impairments are essential to improve postural control and mobility in this population.\n\nThis randomized controlled trial aims to compare the effects of proprioceptive neuromuscular training and sensory re-education on balance and gait performance in patients with diabetic peripheral neuropathy. Participants diagnosed with DPN will be randomly allocated into two groups. Group A will receive sensory re-education, while Group B will undergo a structured proprioceptive training program. Both groups will also receive baseline conventional treatment.\n\nBalance and gait outcomes will be assessed using the Berg Balance Scale and the Dynamic Gait Index at baseline, mid-intervention, and post-intervention. The findings of this study may help determine the more effective rehabilitation approach for improving balance and gait in individuals with diabetic peripheral neuropathy, thereby reducing fall risk and enhancing functional independence.",[86],"Diabetic Peripheral Neuropathy",[28,88,89,90],"Sensory Re-education","Balance","Gait","2026-01-31",{"date":93,"type":94},"2026-02-03","ACTUAL",{"date":96,"type":80},"2026-02-10",{"date":98,"type":80},"2026-03-31",{"name":62,"class":6},1]