[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568672":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":39,"responsibleParty":57,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Zagazig University","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pulsed Radiofrequency (PRF)","EXPERIMENTAL","Participants in this group will receive pulsed radiofrequency (PRF) treatment targeted to the trigeminal nerve. The procedure will involve a standard PRF protocol.",[13],"Procedure: Pulsed Radiofrequency (PRF)",{"label":15,"type":16,"description":17,"interventionNames":18},"Pulsed and Thermal Radiofrequency (PRF + TRF)","ACTIVE_COMPARATOR","Participants in this group will receive a combination of pulsed radiofrequency (PRF) and thermal radiofrequency (TRF). The TRF procedure will involve creating a thermal lesion at a target temperature in addition to the standard PRF treatment protocol.",[19],"Procedure: Pulsed and Thermal Radiofrequency (PRF + TRF)",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Participants will receive pulsed radiofrequency (PRF) treatment targeting the trigeminal nerve to manage pain associated with trigeminal neuralgia. This non-ablative technique uses electrical pulses to modulate nerve function, aiming to provide pain relief without creating a thermal lesion.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants will receive a combination of pulsed radiofrequency (PRF) and thermal radiofrequency (TRF) treatments targeting the trigeminal nerve. This approach combines the non-ablative effects of PRF with the thermal lesioning of TRF to provide long-term pain relief for trigeminal neuralgia.",[15],[30],{"name":31,"affiliation":32,"role":33},"Ahmed A Bessar, MD, PhD","Assistant Professor of Diagnostic and Interventional Radiology, Zagazig Uni.","PRINCIPAL_INVESTIGATOR",[35],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+201000089595","Ahmedawadbessar@gmail.com",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Zagazig University, Faculty of Medicine","RECRUITING","Zagazig","Sharqia Province","44519","Egypt","EG",{"type":49,"coordinates":50},"Point",[51,52],31.502,30.58768,{"lat":52,"lon":51},[55],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":56},"ahmedawadbessar@gmail.com",{"type":33,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ahmed Awad Bessar","Assistant Professor of Diagnostic and Interventional Radiology","100568672","comparison-of-pulsed-and-thermal-radiofrequency-for-trigeminal-neuralgia-100568672",false,"NCT06684275","Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia","Comparison of Pulsed and Thermal Radiofrequency for the Treatment of Trigeminal Neuralgia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18-60 years.\n* Diagnosis of classical trigeminal neuralgia, as per the International Classification of Headache Disorders criteria\n* Patients experiencing unilateral, episodic facial pain for at least six months with a Numeric Rating Scale (NRS) score greater than 6, despite medical treatment.\n* Able to provide informed consent.\n* Agree to follow the study procedures and attend follow-up visits.\n\nExclusion Criteria:\n\n* Patients with secondary trigeminal neuralgia (e.g., due to tumors, multiple sclerosis).\n* Previous surgery or radiofrequency treatment for trigeminal neuralgia.\n* Pregnant or breastfeeding women.\n* Known allergies to anesthetics or other agents used in the procedure.\n* Significant psychiatric disorders that may interfere with pain assessment or study participation.\n* Coagulopathy or use of anticoagulants that contraindicate the procedure.","ALL","18 Years","60 Years",{"count":71,"type":72},60,"ESTIMATED","INTERVENTIONAL",[75],"NA","The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults.\n\nThe main questions it aims to answer are:\n\n* Does PRF or PRF + TRF provide better pain relief for patients with trigeminal neuralgia?\n* What is the safety profile and complication rate of PRF versus PRF + TRF?\n\nResearchers will compare the effects of PRF and PRF + TRF to see if thermal lesioning in addition to pulsed RF provides superior long-term pain relief and reduces the need for analgesic medication.\n\nParticipants will:\n\n* Undergo either PRF or PRF + TRF treatment targeting the trigeminal nerve.\n* Be assessed for pain relief, functional status, and adverse events over a 3-month follow-up period.",[78],"Trigeminal Neuralgia",[78,80,81,82,83,84],"Pulsed Radiofrequency","Thermal Radiofrequency","Neuropathic Pain","Facial Pain","Radiofrequency Ablation","2024-12-29",{"date":87,"type":88},"2024-12-31","ACTUAL",{"date":90,"type":88},"2024-11-10",{"date":92,"type":72},"2025-04-10",{"name":5,"class":6},1]