[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627191":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":289,"collaborators":11,"id":291,"slug":292,"hasResults":293,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":11,"eligibilityCriteria":297,"healthyVolunteers":298,"sex":299,"minAge":300,"maxAge":301,"enrollmentInfo":302,"targetDuration":11,"studyType":305,"phases":306,"briefSummary":308,"conditions":309,"keywords":11,"overallStatus":311,"whyStopped":11,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":316,"completionDateStruct":318,"leadSponsor":320,"locationsCount":321},{"fullName":5,"class":6},"Sir Run Run Shaw Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"A","EXPERIMENTAL",null,[13],"Procedure: Staged surgery group",{"label":15,"type":16,"description":11,"interventionNames":17},"B","PLACEBO_COMPARATOR",[18],"Procedure: Concomitant surgery group",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Staged surgery group","The patient is placed in the supine position, and then a DUS examination of the GSV in the affected limbs will be performed. At the appropriate site, local anesthesia will be performed, and the ultrasound-guided Seldinger technique will be used to puncture the main trunk of the GSV 10cm above and below the knee joint. When the needle puncture is successful, we will insert the guidewire, and a 7F vascular sheath (Terumo) will be inserted along the guidewire. Then, we will insert the radiofrequency catheter and advanced the tip to approximately 2 cm at the junction of the saphenofemoral vein, where it will be left in place. Under ultrasound guidance, the needle will be tightly attached to the GSV sheath, and an anesthetic solution will be injected to treat the swelling until the junction of the saphenofemoral vein will be reached. Then, we will secure the tip of the radiofrequency catheter and switch on the radiofrequency generator and ablated the primary trunk of the GSV in segments.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Concomitant surgery group","While the experimental group receives ablation alone, the control group received 1% polidocanol foam sclerosant injection and\u002For point excision treatment for the pre-marked calf segment branches of the GSV after ablation treatment. Both groups will wear elastic bandages for 24 hours postoperatively, followed by thigh-length class II compression stockings for 1 week after bandage removal.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Meijia Xu","CONTACT","+8619700777750","1341506760@qq.com",[36,52,64,72,85,94,107,119,130,142,155,167,180,193,204,217,229,241,264,273,281],{"facility":37,"status":11,"city":38,"state":39,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"The First Affiliated Hospital of Bengbu Medical University","Bengbu","Anhui","China","CN",{"type":43,"coordinates":44},"Point",[45,46],117.36083,32.94083,{"lat":46,"lon":45},[49],{"name":50,"role":32,"phone":51,"phoneExt":11,"email":11},"Zhaowen Yu","8613309651876",{"facility":53,"status":11,"city":54,"state":55,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Peking University International Hospital","Beijing","Beijing Municipality",{"type":43,"coordinates":57},[58,59],116.39723,39.9075,{"lat":59,"lon":58},[62],{"name":63,"role":32,"phone":11,"phoneExt":11,"email":11},"Qian Wang",{"facility":65,"status":11,"city":54,"state":55,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"Peking University Third Hospital",{"type":43,"coordinates":67},[58,59],{"lat":59,"lon":58},[70],{"name":71,"role":32,"phone":11,"phoneExt":11,"email":11},"Changming Wang",{"facility":73,"status":11,"city":74,"state":75,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":76,"geoPoint":80,"contacts":81},"Guangxi Zhuang Autonomous Region People's Hospital","Nanning","Guangxi",{"type":43,"coordinates":77},[78,79],108.31667,22.81667,{"lat":79,"lon":78},[82],{"name":83,"role":32,"phone":84,"phoneExt":11,"email":11},"Lei Yu","8613387719938",{"facility":86,"status":11,"city":74,"state":75,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":87,"geoPoint":89,"contacts":90},"The First Affiliated Hospital of Guangxi University of Chinese Medicine",{"type":43,"coordinates":88},[78,79],{"lat":79,"lon":78},[91],{"name":92,"role":32,"phone":93,"phoneExt":11,"email":11},"Yaochang Luo","8615907713918",{"facility":95,"status":11,"city":96,"state":97,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Hainan Provincial Hospital of Traditional Chinese Medicine","Haikou","Hainan",{"type":43,"coordinates":99},[100,101],110.34651,20.03421,{"lat":101,"lon":100},[104],{"name":105,"role":32,"phone":106,"phoneExt":11,"email":11},"Chuang Wang","8613514808066",{"facility":108,"status":11,"city":109,"state":110,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"Zhengzhou Central Hospital","Zhengzhou","Henan",{"type":43,"coordinates":112},[113,114],113.64861,34.75778,{"lat":114,"lon":113},[117],{"name":118,"role":32,"phone":11,"phoneExt":11,"email":11},"Bin Song",{"facility":120,"status":11,"city":121,"state":110,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":122,"geoPoint":126,"contacts":127},"Zhoukou Central Hospital","Zhoukou",{"type":43,"coordinates":123},[124,125],114.63333,33.63333,{"lat":125,"lon":124},[128],{"name":129,"role":32,"phone":11,"phoneExt":11,"email":11},"Xianwei Qi",{"facility":131,"status":11,"city":132,"state":133,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":134,"geoPoint":138,"contacts":139},"The First People's Hospital of Chenzhou","Chenzhou","Hunan",{"type":43,"coordinates":135},[136,137],113.03333,25.8,{"lat":137,"lon":136},[140],{"name":141,"role":32,"phone":11,"phoneExt":11,"email":11},"Yide Zheng",{"facility":143,"status":11,"city":144,"state":145,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":146,"geoPoint":150,"contacts":151},"Huai'an First People's Hospital","Huai'an","Jiangsu",{"type":43,"coordinates":147},[148,149],119.01917,33.58861,{"lat":149,"lon":148},[152],{"name":153,"role":32,"phone":154,"phoneExt":11,"email":11},"Gang Xu","8618851258521",{"facility":156,"status":11,"city":157,"state":145,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":158,"geoPoint":162,"contacts":163},"Jiangsu Province Hospital of Traditional Chinese Medicine","Nanjing",{"type":43,"coordinates":159},[160,161],118.77778,32.06167,{"lat":161,"lon":160},[164],{"name":165,"role":32,"phone":166,"phoneExt":11,"email":11},"Weihua Jiang","8613770662060",{"facility":168,"status":11,"city":169,"state":170,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":171,"geoPoint":175,"contacts":176},"The Second Affiliated Hospital of Nanchang University","Nanchang","Jiangxi",{"type":43,"coordinates":172},[173,174],115.85306,28.68396,{"lat":174,"lon":173},[177],{"name":178,"role":32,"phone":179,"phoneExt":11,"email":11},"Weimin Zhou","8613870658585",{"facility":181,"status":11,"city":182,"state":183,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":184,"geoPoint":188,"contacts":189},"The First Affiliated Hospital of Dalian Medical University","Dalian","Liaoning",{"type":43,"coordinates":185},[186,187],121.60222,38.91222,{"lat":187,"lon":186},[190],{"name":191,"role":32,"phone":192,"phoneExt":11,"email":11},"Ming Qi","8618098875991",{"facility":194,"status":11,"city":195,"state":183,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":196,"geoPoint":200,"contacts":201},"The First Affiliated Hospital of China Medical University","Shenyang",{"type":43,"coordinates":197},[198,199],123.43278,41.79222,{"lat":199,"lon":198},[202],{"name":203,"role":32,"phone":11,"phoneExt":11,"email":11},"Jian Zhang",{"facility":205,"status":11,"city":206,"state":207,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":208,"geoPoint":212,"contacts":213},"Dezhou People's Hospital","Dezhou","Shandong",{"type":43,"coordinates":209},[210,211],116.36706,37.44661,{"lat":211,"lon":210},[214],{"name":215,"role":32,"phone":216,"phoneExt":11,"email":11},"Haiqing Wang","8613053420366",{"facility":218,"status":11,"city":219,"state":207,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":220,"geoPoint":224,"contacts":225},"Yantai Yuhuangding Hospital","Yantai",{"type":43,"coordinates":221},[222,223],121.44081,37.47649,{"lat":223,"lon":222},[226],{"name":227,"role":32,"phone":228,"phoneExt":11,"email":11},"Lubin Li","8618653587355",{"facility":230,"status":11,"city":231,"state":207,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":232,"geoPoint":236,"contacts":237},"Zibo First Hospital","Zibo",{"type":43,"coordinates":233},[234,235],118.06333,36.79056,{"lat":235,"lon":234},[238],{"name":239,"role":32,"phone":240,"phoneExt":11,"email":11},"Tong Liu","8613156987626",{"facility":242,"status":11,"city":243,"state":244,"zip":245,"country":40,"countryCode":41,"cosmosGeoPoint":246,"geoPoint":250,"contacts":251},"Sir Run Run Shaw Hospital, Zhejiang University School of Medicine","Hangzhou","Zhejiang","310000",{"type":43,"coordinates":247},[248,249],120.16142,30.29365,{"lat":249,"lon":248},[252,254,256,259,262],{"name":253,"role":32,"phone":33,"phoneExt":11,"email":34},"Meijia Xu, Postgraduate",{"name":255,"role":32,"phone":11,"phoneExt":11,"email":11},"Yuefeng Zhu",{"name":257,"role":258,"phone":11,"phoneExt":11,"email":11},"Yuefeng Zhu, Archiater","PRINCIPAL_INVESTIGATOR",{"name":260,"role":261,"phone":11,"phoneExt":11,"email":11},"Huanhuan Chen, Attending physician","SUB_INVESTIGATOR",{"name":263,"role":261,"phone":11,"phoneExt":11,"email":11},"Qiang Zheng, Certified doctor",{"facility":265,"status":11,"city":243,"state":244,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":266,"geoPoint":268,"contacts":269},"Hangzhou Third People's Hospital",{"type":43,"coordinates":267},[248,249],{"lat":249,"lon":248},[270],{"name":271,"role":32,"phone":272,"phoneExt":11,"email":11},"Luyang Meng","13777831991",{"facility":274,"status":11,"city":243,"state":244,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":275,"geoPoint":277,"contacts":278},"The Second Affiliated Hospital, Zhejiang University School of Medicine",{"type":43,"coordinates":276},[248,249],{"lat":249,"lon":248},[279],{"name":280,"role":32,"phone":11,"phoneExt":11,"email":11},"Zhenjie Liu",{"facility":282,"status":11,"city":283,"state":244,"zip":11,"country":40,"countryCode":41,"cosmosGeoPoint":284,"geoPoint":288,"contacts":11},"Affiliated Hospital of Shaoxing University","Shaoxing",{"type":43,"coordinates":285},[286,287],120.57864,30.00237,{"lat":287,"lon":286},{"type":290,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100627191","comparison-of-radiofrequency-ablation-with-concomitant-or-staged-treatment-for-tributary-varicose-veins-100627191",false,"NCT07445425","Comparison of Radiofrequency Ablation With Concomitant or Staged Treatment for Tributary Varicose Veins","Comparison of Concomitant or Staged Treatment of Tributary Veins for Lower Extremity Varicose Veins: A Multicenter Randomized Controlled Study","Inclusion Criteria:\n\naged between 18 and 80 years; primary unilateral lower limb GSV varicose; hemodynamic classification I and III involvement in tributary veins, tributary veins originating within 15 cm inferior to the knee joint; clinical grade C2-C4; primary trunk diameter of GSV in thigh segment≥3mm to ≤ 15 mm; agree to participate in this study and voluntarily sign an informed consent form.\n\nExclusion Criteria:\n\nBody Mass Index (BMI) ≥35kg\u002Fm2; severe tortuosity or tight adherence of the trunk of the GSV to the skin in the thigh; history of previous varicose vein surgery on the ipsilateral lower limb (investigator allows to be controlled); previous deep vein thrombosis and\u002For calf muscle venous thrombosis; uncorrectable coagulation disorders or significant blood abnormalities (platelets≤30×109\u002FL); allergy to lidocaine or sclerosing agents; ankle-brachial index (ABI) \\\u003C0.6 and\u002For absolute ankle pressure \\\u003C60mmHg; pregnancy or lactation, or intend to have a child in the next year; participation in other clinical trials; anterior saphenous vein start diameter\\>3.5mm; any other patients investigator considers improper to participate in this study.",true,"ALL","18 Years","80 Years",{"count":303,"type":304},206,"ESTIMATED","INTERVENTIONAL",[307],"NA","The purpose of this clinical trial is to know which is better to treat the branch vein at the same time or in stages during radiofrequency ablation. The main questions it aims to answer are:\n\nDoes the patient who did not treat the branch vein in the first stage of operation need to intervene again? Are there any differences in patients' indexes between the two surgical strategies?\n\nParticipants will:\n\nRadiofrequency ablation with or without foam sclerosing agent therapy One week, three months and six months after operation, go to the clinic for a reexamination.\n\nRecord their symptoms",[310],"Varicose Veins of Lower Limb","NOT_YET_RECRUITING","2026-02-26",{"date":314,"type":315},"2026-03-03","ACTUAL",{"date":317,"type":304},"2026-03",{"date":319,"type":304},"2026-12",{"name":5,"class":6},21]