[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635546":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":33,"centralContacts":40,"locations":48,"responsibleParty":71,"collaborators":73,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":32,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":32,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":51,"whyStopped":32,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Khyber Medical University Peshawar","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard Ponseti Casting (Once Weekly)","EXPERIMENTAL","Participants in this arm receive standard Ponseti serial casting once per week (every Monday) until clubfoot correction is achieved. Each casting session includes manipulation followed by application of a plaster cast. Typically 5 to 6 casts are required. When indicated, a tendo Achillis tenotomy is performed under local anesthesia in the clinic, followed by a final cast worn for three weeks. After cast removal, a foot abduction orthosis (Miracle Feet brace) is applied and worn full-time for three months, then nights only until five years of age. Radiological outcome is assessed six weeks after brace fitting.",[13],"Procedure: Ponseti Casting",{"label":15,"type":16,"description":17,"interventionNames":18},"Accelerated Ponseti Casting (Twice Weekly)","ACTIVE_COMPARATOR","Participants in this arm receive accelerated Ponseti serial casting twice per week (every Monday and Friday) until clubfoot correction is achieved. All other elements are identical to the standard arm: manipulation technique, number of casts (typically 5-6), tendo Achillis tenotomy under local anesthesia when indicated, a final cast for three weeks, followed by the same foot abduction orthosis (Miracle Feet brace) with identical wearing schedule. Radiological outcome is assessed six weeks after brace fitting. The only difference from the standard arm is the frequency of cast changes.",[19],"Procedure: Accelerated Ponseti Casting",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ponseti Casting","Participants receive serial manipulation and plaster cast application according to the standard Ponseti technique to correct clubfoot deformity (cavus, adduction, varus, and equinus). A long-leg plaster cast is applied after each manipulation session. Casts are changed either once weekly (every Monday) for the standard group or twice weekly (Monday and Friday) for the accelerated group. Typically 5 to 6 casts are required over the treatment course. When all deformities except equinus are corrected, a percutaneous tendo Achillis tenotomy is performed under local anesthesia in the clinic, followed by a final cast worn continuously for three weeks. After final cast removal, a foot abduction orthosis (Miracle Feet brace) is applied and worn full-time for the first three months, then nights only until the child reaches five years of age. Radiological outcome is assessed six weeks after brace fitting.",[9],[27],"Serial casting, Ponseti method, Ponseti technique",{"type":22,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"Accelerated Ponseti Casting","erial manipulation and long-leg plaster cast applied twice every week (every Monday and Friday) until clubfoot correction is achieved. Typically 5-6 casts are applied over 2.5-3 weeks. This is the only difference compared to the standard arm. Tenotomy is performed under local anesthesia in the clinic when residual equinus remains after serial casting. A tenotomy knife is used to transect the Achilles tendon percutaneously, followed by a final cast for 3 weeks. This procedure is identical in both study arms.",[15],null,[34,37],{"name":35,"affiliation":5,"role":36},"Sikandar Hayat, MBBS, FCPS (Orthopedic Surgery","PRINCIPAL_INVESTIGATOR",{"name":38,"affiliation":39,"role":36},"Dr Khalid Rehman, MBBS","Institute of Public Health & Social Science, Khyber Medical University Peshawar",[41,45],{"name":35,"role":42,"phone":43,"phoneExt":32,"email":44},"CONTACT","03329474849","drsikandar68@gmail.com",{"name":38,"role":42,"phone":46,"phoneExt":32,"email":47},"+92 333 9432032","drkhalidrehman@kmu.edu.pk",[49],{"facility":50,"status":51,"city":52,"state":53,"zip":54,"country":55,"countryCode":56,"cosmosGeoPoint":57,"geoPoint":62,"contacts":63},"Khyber Teaching Hospital","RECRUITING","Peshawar","KPK","25000","Pakistan","PK",{"type":58,"coordinates":59},"Point",[60,61],71.57849,34.008,{"lat":61,"lon":60},[64,67,69],{"name":65,"role":42,"phone":66,"phoneExt":32,"email":44},"Dr Sikandar Hayat, MBBS","92 332 9474849",{"name":38,"role":42,"phone":46,"phoneExt":68,"email":47},"Ali Naqvi",{"name":70,"role":36,"phone":32,"phoneExt":32,"email":32},"Dr Syed Muhammad Shabbir Ali Naqvi, PhD*",{"type":72,"investigatorFullName":32,"investigatorTitle":32,"investigatorAffiliation":32,"oldNameTitle":32,"oldOrganization":32},"SPONSOR",[74],{"name":50,"class":6},"100635546","comparison-of-radiological-outcome-of-conventional-vs-accelerated-ponseti-casting-technique-for-treatment-of-club-foot-100635546",false,"NCT07554092","Comparison of Radiological Outcome of Conventional vs Accelerated Ponseti Casting Technique for Treatment of Club Foot","Comparison of Radiological Outcome of Conventional vs Accelerated Ponseti Casting Technique for Treatment of Club Foot: Randomized Controlled Trial","Inclusion Criteria:\n\n-Both gender with idiopathic club foot with age less than 6 months\n\nExclusion Criteria:\n\n* Syndromic club foot (e.g., associated with arthrogryposis, myelomeningocele, or other genetic syndromes)\n* Previous treatment for club foot (either serial casting or surgical intervention)\n* Any other significant congenital anomaly or medical condition that, in the opinion of the investigator, would interfere with treatment or follow-up","ALL","1 Day","5 Months",{"count":86,"type":87},144,"ESTIMATED","INTERVENTIONAL",[90],"NA","Club foot (congenital talipes equinovarus) is a common birth deformity affecting 1-2 per 1,000 live births, with even higher rates in low-income countries. The standard treatment is the Ponseti method using weekly serial casts, but weekly visits for several weeks can be challenging for families in hot climates or with limited resources. This randomized controlled trial compares the standard once-weekly Ponseti casting with an accelerated twice-weekly casting technique. The primary outcome is radiological correction measured by the lateral talocalcaneal angle (target ≥35°) on standardized foot X-rays taken six weeks after brace fitting. Secondary outcomes include the talocalcaneal index (\\>40) and the tibio-calcaneal (dorsiflexion) angle (60-90°). Babies under six months of age with idiopathic club foot will be randomly assigned to either the standard or accelerated casting group. All other aspects of the Ponseti method (manipulation, number of casts, tenotomy when needed, final cast for three weeks, and foot abduction orthosis) remain identical. Adverse events such as skin problems, swelling, or cast complications will be recorded. The study aims to determine whether accelerated casting achieves better radiographic correction without increasing risks.",[93],"Club Foot",[93,95,96,97],"Ponseti Casting Technique","Randomized controlled trial","Congenital talipes equinovarus","2026-04-21",{"date":100,"type":101},"2026-04-28","ACTUAL",{"date":103,"type":101},"2026-02-01",{"date":105,"type":87},"2026-11-25",{"name":5,"class":6},1]