[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100511499":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":42,"responsibleParty":59,"collaborators":36,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":36,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":36,"maxAge":36,"enrollmentInfo":69,"targetDuration":36,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":36,"overallStatus":45,"whyStopped":36,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Queen Savang Vadhana Memorial Hospital, Thailand","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Letrozole plus Misoprostol","EXPERIMENTAL","We give the Letrozole 10 mg PO daily at day 1-3 prior to Misoprostol 800 mcg SL in day 4.",[13],"Drug: Letrozole",{"label":15,"type":16,"description":17,"interventionNames":18},"Misoprostol","ACTIVE_COMPARATOR","We give only Misoprostol 800 mcg SL.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Letrozole","In the experimental group, we give the Letrozole 10 mg PO daily on the 4th day before Misoprostol 800 mcg SL on the 4th day. In the control group, we give Misoprostol 800 mcg SL on the 4th day.",[9,15],[26],"Femara",[28],{"name":29,"affiliation":5,"role":30},"ชื่นฤทัย ยี่เขียน, Ph.D.","STUDY_CHAIR",[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Sutinee Srimahachota, M.D.","CONTACT","0847202666",null,"srimahachota@gmail.com",{"name":39,"role":34,"phone":40,"phoneExt":36,"email":41},"Chuenrutai Yeekian, Ph.D.","0818624534","jayeekian88@gmail.com",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Sutinee Srimahachota","RECRUITING","Bangkok","Yannawa","10120","Thailand","TH",{"type":52,"coordinates":53},"Point",[54,55],100.50144,13.75398,{"lat":55,"lon":54},[58],{"name":44,"role":34,"phone":35,"phoneExt":36,"email":37},{"type":60,"investigatorFullName":36,"investigatorTitle":36,"investigatorAffiliation":36,"oldNameTitle":36,"oldOrganization":36},"SPONSOR","100511499","comparison-of-rate-of-complete-abortion-between-letrozole-plus-misoprostol-vs-misoprostol-alone-100511499",false,"NCT05940233","Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone","Comparison of Rate of Complete Abortion Between Letrozole Plus Misoprostol vs Misoprostol Alone in First Trimester Pregnancy","Inclusion Criteria:\n\n* Diafnoed Early pregnancy loss by TVS according to ACOG Practice bulletin 2018\n* GA \\\u003C= 14 weeks\n* Os open \\\u003C= 1 cm and no conceptus per os\n* Hematicrit \\>= 30\n* Systolic blood pressure \\>= 95 mmHg\n* Informed consent done and can follow up and comunicate in Thai language\n\nExclusion Criteria:\n\n* Allerguc to Letrozole or Misoprostol\n* Intrauterine contraceptive device use\n* Breast feeding\n* Diagnoed with ectopic pregnancy or undiagnoed adnexal mass\n* Severe or recurrent liver disease or AST or ALT more than or equal to 3 times of upper normal limit\n* Multiple pregnancy\n* Myoma uteri that involves the endometrium ex. Submucous myoma uteri\n* Thromboembolism or has a history of thromboembolism\n* Serum creatinine \\>= 2","FEMALE",{"count":70,"type":71},70,"ESTIMATED","INTERVENTIONAL",[74],"NA","Comparison of rate of complete abortion between Letrozole plus Misoprostol versus Misoprostol alone in first trimester pregnancy",[77],"Medical; Abortion, Fetus","2024-11-04",{"date":80,"type":81},"2024-11-06","ACTUAL",{"date":83,"type":81},"2023-06-30",{"date":85,"type":71},"2025-05-30",{"name":5,"class":6},1]