[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621268":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":44,"responsibleParty":63,"collaborators":29,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":29,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":29,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":87,"overallStatus":47,"whyStopped":29,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Kayseri City Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Erector Spinae Plane Block","ACTIVE_COMPARATOR","Standard preoperative monitoring, including ECG, SpO₂, and non-invasive blood pressure (NIBP), will be applied under operating room conditions. Patients will be positioned in the lateral decubitus position with the operative side facing upward. A PHILIPS ClearVue 550 ultrasound device with a high-resolution linear probe (12-5 MHz) will be used. The probe and cable will be covered with a sterile sheath, sterile ultrasound gel will be applied, and skin antisepsis will be achieved using povidone-iodine.\n\nThe transverse process beneath the erector spinae muscle will be targeted. A 22G atraumatic, nerve stimulator-equipped block needle (B. Braun Stimuplex® Ultra 360, 0.7 × 80 mm) will be advanced in-plane from lateral to medial. After confirmation of correct placement by saline hydrodissection, 35 mL of 0.25% bupivacaine will be injected slowly, and longitudinal spread will be observed. Block success will be assessed using the pinprick test.",[13],"Procedure: Erector Spinae Plane Block",{"label":15,"type":10,"description":16,"interventionNames":17},"SAPB + PECS II Technique","Standard monitoring will be applied. Patients will be placed in the supine position with the ipsilateral arm abducted. Using the same ultrasound equipment, the PECS II block will be performed first. The needle will be advanced in-plane between the pectoralis minor and serratus anterior muscles, and 15 mL of 0.25% bupivacaine will be injected after hydrodissection. Both blocks will be performed through a single skin puncture (single needle entry site); without withdrawing the needle from the skin, it will be redirected under ultrasound guidance to access the second target fascial plane. Subsequently, the SAPB will be performed by advancing the probe to the 5th or 6th rib level. The needle will be placed beneath the serratus anterior muscle, and 20 mL of 0.25% bupivacaine will be injected following confirmation of the correct fascial plane. Block efficacy will again be assessed using the pinprick test.",[18],"Procedure: SAPB + PECS II Technique",[20,26],{"type":21,"name":15,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Investigators will perform both blocks with a single injection.",[15],[25],"group 2",{"type":21,"name":9,"description":27,"armGroupLabels":28,"otherNames":29},"Investigators will perform the block before the patient receives general anesthesia and investigators will check it with the pinprick test.",[9],null,[31],{"name":32,"affiliation":5,"role":33},"Çiğdem Ünal Kantekin, Associate Professor of Medicin","PRINCIPAL_INVESTIGATOR",[35,41],{"name":36,"role":37,"phone":38,"phoneExt":39,"email":40},"Erdoğan Rahmi Çinçin, Resident Doctor","CONTACT","+90538 862 31 08","+903523157700","erdo.cincin@gmail.com",{"name":32,"role":37,"phone":42,"phoneExt":39,"email":43},"+905054433056","drcgdm@gmail.com",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":29,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Kasyeri City Hospital","RECRUITING","Kayseri","Kocasinan","38080","Turkey (Türkiye)",{"type":53,"coordinates":54},"Point",[55,56],35.48528,38.73222,{"lat":56,"lon":55},[59],{"name":60,"role":37,"phone":61,"phoneExt":39,"email":62},"günhan gökahmetoğlu, Professor of Medicine","+905336314488","gunhangok@gmail.com",{"type":33,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":29,"oldOrganization":29},"Erdoğan Rahmi Çinçin","Research assistant Doctor","100621268","comparison-of-the-analgesic-efficacy-of-erector-spinae-plane-block-in-breast-conserving-surgery-versus-serratus-anterior-block-combined-with-additional-pecto-intercostal-ii-block-100621268",false,"NCT07368413","Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block","Comparison of Analgesic Efficacy and Opioid Consumption of Erector Spinae Plane Block Versus Serratus Anterior Block With Additional Pecto-Intercostal II Block in Breast-Conserving Surgery","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* ASA physical status I-III\n* No history of bleeding or coagulation disorders\n* Absence of neuropathy\n* Preoperative breast region NRS score \\\u003C 4\n\nExclusion Criteria:\n\n* systemic or regional infection\n* known allergy to local anesthetics\n* Unwillingness to participate in the study","FEMALE","18 Years","75 Years",{"count":77,"type":78},70,"ESTIMATED","INTERVENTIONAL",[81],"NA","This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and postoperative opioid consumption in patients undergoing breast cancer surgery. Seventy patients (ASA I-III, aged 18-75 years) will be randomized into two groups using the sealed envelope method. Ultrasound-guided blocks will be performed preoperatively by the same anesthesiologist, with Group 1 receiving ESPB and Group 2 receiving a combined SAPB + PECS II technique performed through a single skin puncture (single needle entry site) with sequential injections into the two target fascial planes. All patients will undergo surgery under general anesthesia and receive postoperative analgesia via morphine patient-controlled analgesia. Pain scores and total opioid consumption will be statistically analyzed, with p \\\u003C 0.05 considered significant.",[84,85,86],"Pain Management in Breast Surgery","Pain After Surgery","Regional Anaesthesia",[88,89,86,90,91,9],"breast surgery","pain","Serratus Anterior Plane Block","Pectoral Nerve Block Type 2","2026-04-20",{"date":94,"type":95},"2026-04-21","ACTUAL",{"date":97,"type":95},"2026-04-10",{"date":99,"type":78},"2026-07-31",{"name":5,"class":6},1]