[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637598":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":37,"locations":45,"responsibleParty":59,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":48,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Al-Hawash Private University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Miswak Side","ACTIVE_COMPARATOR","50% of the mouth (Randomized half) assigned to be cleaned using the natural Miswak.",[13],"Device: Natural Miswak (Al-Kureysh, Pakistan)",{"label":15,"type":10,"description":16,"interventionNames":17},"Manual Toothbrush Side","The contralateral randomized side of the jaw assigned to be cleaned using a conventional manual toothbrush.",[18],"Device: Manual Toothbrush (Colgate Zig Zag, China)",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Natural Miswak (Al-Kureysh, Pakistan)","* Preparation: 1-2 cm of outer bark removed, soaked in water for 10-15 mins, and fibers frayed.\n* Technique: Vertical strokes (gum to tooth), horizontal on occlusal, focusing around brackets.\n* Duration: 3 to 5 minutes.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Manual Toothbrush (Colgate Zig Zag, China)","* Technique: Modified Bass Technique (bristles at 45-degree angle to gingival margin, short vibratory movements) modified to brush above and below orthodontic brackets.\n* Duration: 3 to 5 minutes.",[15],[31,34],{"name":32,"affiliation":5,"role":33},"Ali Abu Sulaiman","STUDY_CHAIR",{"name":35,"affiliation":5,"role":36},"Fida Kaseeh, Ph.D. in Oral Medicine","PRINCIPAL_INVESTIGATOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},"Ali Abu Sulaiman, Ph.D. in Periodontology","CONTACT","+963956790836","dr.ali.abousulaiman@hpu.edu.sy",{"name":35,"role":40,"phone":25,"phoneExt":25,"email":44},"fidakaseeh@hpu.edu.sy",[46],{"facility":47,"status":48,"city":49,"state":25,"zip":25,"country":50,"countryCode":25,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Al-Hawash Private University, Faculty of Dentistry","RECRUITING","Homs","Syria",{"type":52,"coordinates":53},"Point",[54,55],36.72559,34.72405,{"lat":55,"lon":54},[58],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},{"type":60,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100637598","comparison-of-the-effectiveness-of-miswak-and-manual-toothbrush-in-removing-dental-plaque-in-fixed-orthodontic-patients-100637598",false,"NCT07619014","Comparison of the Effectiveness of Miswak and Manual Toothbrush in Removing Dental Plaque in Fixed Orthodontic Patients","Comparison of the Effectiveness of Miswak and Manual Toothbrush in Removing Dental Plaque in Fixed Orthodontic Patients: A Randomized Split-Mouth Clinical Trial","Inclusion Criteria:\n\n* Patients aged between 18 and 30 years old.\n* Presence of fixed orthodontic appliances (brackets and wires) on both upper and lower arches.\n* Good general systemic health with the absence of any medical conditions that might affect oral health status.\n\nExclusion Criteria:\n\n* Presence of advanced or aggressive periodontal diseases.\n* Current smokers.\n* Use of antimicrobial or antibacterial mouthwashes within 24 hours prior to the study session.\n* Systemic antibiotic intake within the past 2 weeks preceding the experiment.\n* Any physical or motor disability that could hinder the patient's capacity to perform proper tooth brushing.",true,"ALL","18 Years","30 Years",{"count":73,"type":74},90,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study compares the immediate plaque removal efficacy of the natural Miswak versus a traditional manual toothbrush using the Modified Bass technique among orthodontic patients. The main question it aims to answer is: Are there statistically significant differences in the post-brushing plaque index reduction between the dental arch side cleaned with Miswak and the contralateral side cleaned with a manual toothbrush?",[80,81],"Dental Plaque","Orthodontic Patients",[83,84,85,86,81,87],"Toothbursh","Miswak","Siwak","Dental plaque","Braces","2026-05-31",{"date":90,"type":91},"2026-06-03","ACTUAL",{"date":93,"type":91},"2026-05-01",{"date":95,"type":74},"2026-08-30",{"name":5,"class":6},1]