[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635333":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":33,"centralContacts":38,"locations":47,"responsibleParty":64,"collaborators":33,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":33,"eligibilityCriteria":72,"healthyVolunteers":69,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":33,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":33,"overallStatus":85,"whyStopped":33,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Bahçeşehir University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Sham MRT + Clinical Pilates","SHAM_COMPARATOR","Participants in this group will receive sham myofascial release technique combined with Clinical Pilates exercises. The sham intervention will involve light manual contact without sufficient pressure or technique to produce therapeutic effects. The Clinical Pilates program will be based on core stabilization principles and applied for 6 weeks, 2 sessions per week.",[13,14],"Other: Sham Myofascial Release Technique","Other: Clinical Pilates Exercise",{"label":16,"type":17,"description":18,"interventionNames":19},"MRT + Clinical Pilates","EXPERIMENTAL","Participants in this group will receive Myofascial Release Technique (MRT) combined with a Clinical Pilates exercise program. MRT will be applied to the lumbar and thoracolumbar regions using manual techniques aimed at improving fascial mobility and reducing tissue restriction. The Clinical Pilates program will focus on core stabilization, postural control and flexibility. The intervention will be administered for 6 weeks, 2 sessions per week",[20,14],"Other: Myofascial Release Technique (MRT)",[22,29,34],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"Myofascial Release Technique (MRT)","Myofascial Release Technique (MRT) will be applied manually to the lumbar and thoracolumbar regions to improve fascial mobility, reduce soft tissue restrictions, and decrease pain. The technique will be delivered for 6 weeks, 2 sessions per week, by a trained physiotherapist.",[16],[27,28],"MRT","Manual Myofascial Release",{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Sham Myofascial Release Technique","Sham Myofascial Release Technique will be applied to the lumbar and thoracolumbar regions using light manual contact without therapeutic pressure or specific myofascial release techniques. The intervention is designed to mimic the real treatment in terms of time and therapist contact, but without producing physiological therapeutic effects. It will be administered for 6 weeks, 2 sessions per week by a trained physiotherapist.",[9],null,{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":33},"Clinical Pilates Exercise","The Clinical Pilates program will focus on trunk stabilization, core muscle activation, postural control, flexibility, and functional movement training. Exercises will be individually tailored and progressed according to participant tolerance. The program will be administered for 6 weeks, 2 sessions per week under physiotherapist supervision.",[16,9],[39,44],{"name":40,"role":41,"phone":42,"phoneExt":33,"email":43},"Zerrin Yılmaz, MSc","CONTACT","+905349279167","zerrin.yilmaz@ou.bau.edu.tr",{"name":45,"role":41,"phone":33,"phoneExt":33,"email":46},"Cemile Ayşe GÖRMELİ, PhD","cemileayse.gormeli@bau.edu.tr",[48],{"facility":49,"status":33,"city":50,"state":50,"zip":51,"country":52,"countryCode":33,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Bahçeşehir University, Faculty of Health Sciences, Physiotherapy Laboratory","Istanbul","34353","Turkey (Türkiye)",{"type":54,"coordinates":55},"Point",[56,57],28.94966,41.01384,{"lat":57,"lon":56},[60,61,62],{"name":40,"role":41,"phone":42,"phoneExt":33,"email":43},{"name":45,"role":41,"phone":33,"phoneExt":33,"email":46},{"name":40,"role":63,"phone":33,"phoneExt":33,"email":33},"PRINCIPAL_INVESTIGATOR",{"type":63,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"Zerrin Yilmaz","Physiotherapist, PhD Candidate","100635333","comparison-of-the-effectiveness-of-myofascial-release-technique-and-pilates-exercises-in-chronic-non-specific-low-back-pain-100635333",false,"NCT07551323","Comparison of the Effectiveness of Myofascial Release Technique and Pilates Exercises in Chronic Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Chronic non-specific low back pain lasting at least 3 months\n* No clinical signs of nerve root compression or neurological deficit\n* Aged 18-45 years\n* No physical therapy or manual therapy for low back pain in the last 1 month\n* Pain intensity of at least 3 on the Visual Analog Scale (VAS) in the last week\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Systemic, neurological, or orthopedic conditions limiting exercise participation\n* Lumbar radiculopathy or severe spinal pathology\n* History of lumbar spine surgery\n* Unhealed fracture or recent surgical intervention\n* Rheumatologic or inflammatory diseases\n* Neurological disorders affecting movement or balance\n* Participation in any physiotherapy or rehabilitation program in the last 6 months\n* Pregnancy or postpartum period within the last 6 months","ALL","18 Years","45 Years",{"count":77,"type":78},30,"ESTIMATED","INTERVENTIONAL",[81],"NA","Objective:\n\nTo evaluate the effectiveness of adding Myofascial Release Technique (MRT) to Clinical Pilates in adults with chronic non-specific low back pain (CNSLBP).\n\nHypothesis:\n\nMRT combined with Pilates will lead to greater improvements in pain, functional disability, and soft tissue mobility compared to Pilates alone.\n\nDesign \\& Intervention:\n\nRandomized controlled trial. Participants (18-45 years) will be randomly assigned to:\n\nMRT + Clinical Pilates Clinical Pilates only for 6 weeks (2 sessions\u002Fweek).\n\nOutcomes:\n\nPrimary: Pain (VAS), ultrasonographic thickness (multifidus \\& thoracolumbar fascia) Secondary: Disability (ODI), lumbar mobility, balance\n\nEligibility:\n\nAdults with CNSLBP ≥3 months; excluding spinal surgery, rheumatic disease, and pregnancy.",[84],"Chronic Non-specific Low Back Pain","NOT_YET_RECRUITING","2026-04-24",{"date":88,"type":89},"2026-04-29","ACTUAL",{"date":91,"type":78},"2026-04-10",{"date":93,"type":78},"2027-03-01",{"name":5,"class":6},1]