[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602456":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":38,"responsibleParty":56,"collaborators":24,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":24,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Ankara Etlik City Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intrathecal Morphine","ACTIVE_COMPARATOR","An intrathecal injection of morphine 300μg will be administered at the L3-L4 or L4-L5 level.\n\nIn the intraoperative period, intravenous meperidine 0.5 mg\u002Fkg will be given 30min before the end of surgery.",[13],"Procedure: Intrathecal Morphine",{"label":15,"type":10,"description":16,"interventionNames":17},"Bi-level Erector Spinae Plane Block","After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T8 spinous process, 10 ml of 0.25% bupivacaine hydrochloride will be injected cauda-cranially into the interfacial space below the erector spinae muscle, above the transverse process. Next, the needle will be withdrawn till subcutaneously and the linear US probe will be placed 2-3 cm lateral to the T10 spinous process. Finally, 10 ml of 0.25% bupivacaine hydrochloride will be injected cranio-caudally into the interfacial space below the erector spinae muscle, above the transverse process.\n\nThis procedure will be performed bilaterally. A total of 40 ml of 0.25% bupivacaine will be injected for bilateral and bi-level ESPB application.\n\nIn the intraoperative period, intravenous meperidine 0.5 mg\u002Fkg will be given 30min before the end of surgery.",[18],"Procedure: Bi-level Erector Spinae Plane Block",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","An intrathecal injection of morphine 300μg will be administered at the L3-L4 or L4-L5 level.\n\nAdditionally, in the postoperative period a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Bi-level erector spinae plane block will be performed on the patients using a total of 40 ml of 0.25% bupivacaine under ultrasound guidance.\n\nAdditionally, in the postoperative period a dexketoprofen dose of 50 mg twice daily were administered iv for multimodal analgesia.",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Atakan Sezgi","CONTACT","00905323327000","kansezgi@gmail.com",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},"Jülide Ergil","00905323469216","julideergil@hotmail.com",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":24,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Altındağ","Ankara","06000","Turkey (Türkiye)",{"type":46,"coordinates":47},"Point",[48,49],32.92254,39.96673,{"lat":49,"lon":48},[52,54],{"name":53,"role":31,"phone":32,"phoneExt":24,"email":33},"Atakan Sezgi, M.D.",{"name":55,"role":31,"phone":36,"phoneExt":24,"email":37},"Jülide Ergil, Professor",{"type":57,"investigatorFullName":30,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100602456","comparison-of-the-postoperative-analgesic-effects-of-itm-and-bi-level-espb-in-liver-transplantation-donors-100602456",false,"NCT07123740","Comparison of the Postoperative Analgesic Effects of ITM and Bi-level ESPB in Liver Transplantation Donors","Comparison of the Postoperative Analgesic Effects of Intrathecal Morphine and Bi-level Erector Spinae Plane Block in Liver Transplantation Donors","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* American Society of Anesthesiologists (ASA) score I-II\n* Body Mass Index (BMI) between 18-30 kg\u002Fm2\n\nExclusion Criteria:\n\n* Patients under 18 and over 65 years of age\n* ASA score III and above\n* Patients with a history of bleeding diathesis\n* BMI below 18 or above 30 kg\u002Fm2","ALL","18 Years","65 Years",{"count":70,"type":71},60,"ESTIMATED","INTERVENTIONAL",[74],"NA","Liver transplantation is a life-saving procedure for patients with end-stage liver disease, and postoperative pain management is critical for optimizing donor recovery and overall outcomes. Poorly controlled pain following donor hepatectomy may reduce quality of life, delay mobilization, and contribute to the development of chronic pain syndromes.\n\nRegional anesthesia techniques, such as intrathecal morphine and erector spinae plane block, have been utilized to enhance postoperative analgesia and reduce perioperative opioid requirements, potentially minimizing opioid-related adverse effects.\n\nIn this study, we aimed to compare the postoperative analgesic efficacy of intrathecal morphine and Bi-level erector spinae plane block in living liver donors.",[77,78],"Liver Transplantation","Pain Management",[77,9,80],"Erector Spinae Plane Block","2025-08-18",{"date":83,"type":84},"2025-08-19","ACTUAL",{"date":81,"type":84},{"date":87,"type":71},"2026-07-24",{"name":5,"class":6},1]