[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100455141":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":32,"responsibleParty":51,"collaborators":18,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":55,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":18,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":35,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Vaginal Repair with Leuprorelin","EXPERIMENTAL","CSD patients were treated with vaginal repair of CSD in combination with Leuprorelin . In the group of Vaginal Repair With Leuprorelin, the patients will get 3 times of Leuprorelin per 4 weeks perioperation. The detailed procedure of Vaginal Repair has been described in our previous study.",[13],"Drug: Leuprorelin",{"label":15,"type":16,"description":17,"interventionNames":18},"Vaginal Repair without Leuprorelin","NO_INTERVENTION","The detailed procedure of Vaginal Repair has been described in our previous study.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DRUG","Leuprorelin","Leuprorelin will be used to postpone period after vaginal repair.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Wang Xipeng","CONTACT","+862125078999","6143","steveoizzie@icloud.com",[33],{"facility":34,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Shanghai Jiaotong University xinhua hospital","RECRUITING","Shanghai","Shanghai Municipality","200092","China","CN",{"type":42,"coordinates":43},"Point",[44,45],121.45806,31.22222,{"lat":45,"lon":44},[48],{"name":49,"role":28,"phone":50,"phoneExt":18,"email":18},"Xipeng Wang","13817806602",{"type":52,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100455141","comparison-of-the-therapeutic-effects-of-vaginal-repair-with-leuprorelin-and-vaginal-repair-in-the-treatment-of-cesarean-section-scar-defect-100455141",false,"NCT05206682","Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect","Inclusion Criteria:\n\n1. Clearly diagnosed with CSD complicated with adenomyosis\n2. Experiencing clinical features of abnormal uterine bleeding, prolonged menstrual flow (the duration of menstruation is more than 10 days).\n3. The thickness of the remaining muscular layer of CSD was less than 3 mm.\n4. Normal range of blood sugar and insulin\n5. No serious medical problems (important viscera function in the normal range).\n6. uterine fibroids no more than 5cm\n7. Sign the informed consent.\n\nExclusion Criteria:\n\n1. Indefinite diagnosis.\n2. Malignant tumors.\n3. With severe medical problems (severe liver disease, kidney disease, respiratory diseases, heart disease or uncontrolled diabetes, epilepsy, etc., dysfunction of important organs).\n4. Pregnant.\n5. Mental diseases.\n6. Allergy to the any ingredients of Leuprorelin\n7. Unwilling to comply with the research plan.","FEMALE","18 Years","50 Years",{"count":63,"type":64},94,"ESTIMATED","INTERVENTIONAL",[67],"NA","GnRH-a will be used to postpone period after vaginal repair for Cesarean Section Scar Defect（CSD） patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transvaginal surgery without GnRH-a, whether delayed period improving the CSD prognosis will be assessed.",[70],"Cesarean Section; Dehiscence",[72,73,74],"Cesarean Section Scar Defect","Zoladex","vaginal repair","2026-04-22",{"date":77,"type":78},"2026-04-24","ACTUAL",{"date":80,"type":78},"2023-05-01",{"date":82,"type":64},"2027-12-30",{"name":5,"class":6},1]